2010
Rethinking Prevention of HIV Type 1 Infection
Burns DN, Dieffenbach CW, Vermund SH. Rethinking Prevention of HIV Type 1 Infection. Clinical Infectious Diseases 2010, 51: 725-731. PMID: 20707698, PMCID: PMC3071685, DOI: 10.1086/655889.Peer-Reviewed Original Research
2009
Early Neurologic Abnormalities Associated with Human T-Cell Lymphotropic Virus Type 1 Infection in a Cohort of Peruvian Children
Kendall EA, González E, Espinoza I, Tipismana M, Verdonck K, Clark D, Vermund SH, Gotuzzo E. Early Neurologic Abnormalities Associated with Human T-Cell Lymphotropic Virus Type 1 Infection in a Cohort of Peruvian Children. The Journal Of Pediatrics 2009, 155: 700-706. PMID: 19628219, PMCID: PMC2764792, DOI: 10.1016/j.jpeds.2009.05.027.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge DistributionAge of OnsetCase-Control StudiesChildChild, PreschoolCohort StudiesConfidence IntervalsFemaleHTLV-I InfectionsHuman T-lymphotropic virus 1HumansInfectious Disease Transmission, VerticalMaleNeurologic ExaminationOdds RatioParaparesisParaparesis, Tropical SpasticPeruPrevalenceProbabilityRisk AssessmentSeverity of Illness IndexSex DistributionSpinal Cord DiseasesTime FactorsUrination DisordersConceptsParesthesia/dysesthesiaHTLV-1 infectionNeurologic abnormalitiesInfective dermatitisHTLV-1Lumbar painHuman T-cell lymphotropic virus type 1 infectionMyelopathy/tropical spastic paraparesisHuman T-cell lymphotropic virus type 1Virus type 1 infectionPeruvian childrenAbnormal neurologic findingsEarly Neurologic AbnormalitiesLower extremity hyperreflexiaStandardized neurologic examinationType 1 infectionTropical spastic paraparesisWeakness/fatigueHTLV-1 statusVirus type 1Uninfected childrenNeurologic findingsNeurologic symptomsUrinary disturbanceNeurologic examination
2007
Early Infant Human Immunodeficiency Virus Type 1 Detection Suitable for Resource-Limited Settings with Multiple Circulating Subtypes by Use of Nested Three-Monoplex DNA PCR and Dried Blood Spots
Zhang Q, Wang L, Jiang Y, Fang L, Pan P, Gong S, Yao J, Tang YW, Vermund SH, Jia Y. Early Infant Human Immunodeficiency Virus Type 1 Detection Suitable for Resource-Limited Settings with Multiple Circulating Subtypes by Use of Nested Three-Monoplex DNA PCR and Dried Blood Spots. Journal Of Clinical Microbiology 2007, 46: 721-726. PMID: 18077639, PMCID: PMC2238144, DOI: 10.1128/jcm.01539-07.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsBloodBlotting, WesternChinaDNA PrimersDNA, ViralEnv Gene Products, Human Immunodeficiency VirusGag Gene Products, Human Immunodeficiency VirusHIV AntibodiesHIV InfectionsHIV-1HumansInfantInfant, NewbornPol Gene Products, Human Immunodeficiency VirusPolymerase Chain ReactionReproducibility of ResultsSensitivity and SpecificitySpecimen HandlingConceptsHIV-1 subtypesMonths of ageDiverse HIV-1 subtypesEarly infant HIV-1 diagnosisHuman immunodeficiency virus type 1 (HIV-1) infectionHIV-1 DNA PCRVirus type 1 infectionDNA PCRType 1 infectionHIV-1 diagnosisDiverse HIV-1Resource limited settingsAntibody enzyme immunoassayBlood spot samplesInfected mothersMaternal antibodiesCRF01-AEDBS specimensEpidemiologic dataHIV-1Deceased infantsInfantsCRF07-BCMultiple subtypesBlood spotsSeroincidence of Recent Human Immunodeficiency Virus Type 1 Infections in China▿
Xiao Y, Jiang Y, Feng J, Xu W, Wang M, Funkhouser E, Vermund SH, Jia Y. Seroincidence of Recent Human Immunodeficiency Virus Type 1 Infections in China▿. MSphere 2007, 14: 1384-1386. PMID: 17671229, PMCID: PMC2168114, DOI: 10.1128/cvi.00356-06.Peer-Reviewed Original Research
2002
Correlates of Nontransmission in US Women at High Risk of Human Immunodeficiency Virus Type 1 Infection through Sexual Exposure
Skurnick JH, Palumbo P, DeVico A, Shacklett BL, Valentine FT, Merges M, Kamin-Lewis R, Mestecky J, Denny T, Lewis GK, Lloyd J, Praschunus R, Baker A, Nixon DF, Stranford S, Gallo R, Vermund SH, Louria DB. Correlates of Nontransmission in US Women at High Risk of Human Immunodeficiency Virus Type 1 Infection through Sexual Exposure. The Journal Of Infectious Diseases 2002, 185: 428-438. PMID: 11865394, PMCID: PMC2743095, DOI: 10.1086/338830.Peer-Reviewed Original ResearchConceptsSexual exposureSuppressive activityHuman immunodeficiency virus type 1 (HIV-1) infectionHigher CD8 cell countsHIV-1-suppressive activitySingle-cell cytokine productionHuman immunodeficiency virus type 1Macrophage inflammatory protein-1 betaVirus type 1 infectionHIV-positive male partnersInflammatory protein-1 betaMale partnersImmunodeficiency virus type 1CD4 cell responseCD8 cell countsHIV-positive donorsHIV-positive partnerHIV-negative partnersType 1 infectionInterferon-gamma secretionHIV-suppressive activityVirus type 1Apparent protective roleHIV antigenLocal antibodies
1998
Behavioral and Demographic Risk Factors for Transmission of Human Immunodeficiency Virus Type 1 in Heterosexual Couples: Report from the Heterosexual HIV Transmission Study
Skurnick J, Kennedy C, Perez G, Abrams J, Vermund S, Denny T, Wright T, Quinones M, Louria D. Behavioral and Demographic Risk Factors for Transmission of Human Immunodeficiency Virus Type 1 in Heterosexual Couples: Report from the Heterosexual HIV Transmission Study. Clinical Infectious Diseases 1998, 26: 855-864. PMID: 9564464, DOI: 10.1086/513929.Peer-Reviewed Original ResearchConceptsHIV-concordant couplesRisk factorsAnal sexHuman immunodeficiency virus type 1 (HIV-1) infectionHeterosexual HIV transmission studyHuman immunodeficiency virus type 1Virus type 1 infectionImmunodeficiency virus type 1HIV transmission studyHIV-discordant couplesStage of diseaseType 1 infectionBehavioral risk factorsUnprotected vaginal sexDemographic risk factorsMultivariate logistic modelVirus type 1Sexual risk behaviorsPartner infectionUninfected womenAntiviral therapyHIV transmissionDiscordant couplesPap smearGrade 2Analysis of Intercurrent Human Immunodeficiency Virus Type 1 Infections in Phase I and II Trials of Candidate AIDS Vaccines
Graham B, McElrath M, Connor R, Schwartz D, Gorse G, Keefer M, Mulligan M, Matthews T, Wolinsky S, Montefiori D, Vermund S, Lambert J, Corey L, Belshe R, Dolin R, Wright P, Korber B, Wolff M, Fast P, Group A. Analysis of Intercurrent Human Immunodeficiency Virus Type 1 Infections in Phase I and II Trials of Candidate AIDS Vaccines. The Journal Of Infectious Diseases 1998, 177: 310-309. PMID: 9466516, DOI: 10.1086/514209.Peer-Reviewed Original ResearchMeSH KeywordsAdultAIDS VaccinesAmino Acid SequenceCD4 Lymphocyte CountFemaleHIV AntibodiesHIV Envelope Protein gp120HIV InfectionsHIV-1HumansImmunity, ActiveIncidenceMaleMiddle AgedMolecular Sequence DataNeutralization TestsPeptide FragmentsRisk-TakingSequence AnalysisSubstance Abuse, IntravenousViral LoadConceptsHIV-1 infectionHuman immunodeficiency virus type 1 (HIV-1) infectionVirus type 1 infectionCandidate AIDS vaccinesType 1 infectionAIDS vaccinePhase IHigh-risk sexual exposureVaccine-induced immune responsesComplete immunization scheduleEarly clinical courseCD4 lymphocyte countIntravenous drug useV3 loop amino acid sequencesUninfected subjectsVaccine recipientsLymphocyte countClinical courseImmunization scheduleSexual exposureVirus loadImmune responseControl groupDrug useInfection
1994
Rising HIV-1 prevalence among sexually transmitted disease clinic attenders in Jamaica: traumatic sex and genital ulcers as risk factors.
Figueroa JP, Brathwaite A, Morris J, Ward E, Peruga A, Blattner W, Vermund SH, Hayes R. Rising HIV-1 prevalence among sexually transmitted disease clinic attenders in Jamaica: traumatic sex and genital ulcers as risk factors. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1994, 7: 310-6. PMID: 8106971.Peer-Reviewed Original ResearchConceptsGenital ulcersHIV infectionSyphilis serologyHIV Type 1 InfectionHuman immunodeficiency virus (HIV) infectionMultiple logistic regression analysisHIV-1 prevalenceImmunodeficiency virus infectionType 1 infectionComprehensive health centersLogistic regression analysisDisease clinic attendersHeterosexual menMore sex partnersDisease complaintsClinic attendersIndependent associationRisk factorsHealth centersVirus infectionPresent complaintsSex partnersUlcersAge adjustmentPast month
1991
Estimating the 1978–1990 and Future Spread of Human Immunodeficiency Virus Type 1 in Subgroups of Homosexual Men
Hoover D, Munoz A, Carey V, Chmiel J, Taylor J, Margolick J, Kingsley L, Vermund S. Estimating the 1978–1990 and Future Spread of Human Immunodeficiency Virus Type 1 in Subgroups of Homosexual Men. American Journal Of Epidemiology 1991, 134: 1190-1205. PMID: 1746529, DOI: 10.1093/oxfordjournals.aje.a116022.Peer-Reviewed Original ResearchConceptsSeroconversion ratesHomosexual menHuman immunodeficiency virus type 1 (HIV-1) infectionHuman immunodeficiency virus type 1Virus type 1 infectionImmunodeficiency virus type 1Kaplan-Meier methodHIV-1 infectionType 1 infectionAge 55 yearsHIV-1 epidemicVirus type 1AIDS diagnosisSeroconversionAnnual hazardHematologic variablesAge 55Type 1Survival methodsBisexual menHomosexual populationCohortMenAgeInfection