2023
Validation of “Life's Essential 8” Metrics With Cardiovascular Structural Status in Children: The PROC Study in China
Shu W, Li M, Xiao H, Amaerjiang N, Khattab N, Zunong J, Guan M, Vermund S, Hu Y. Validation of “Life's Essential 8” Metrics With Cardiovascular Structural Status in Children: The PROC Study in China. Journal Of The American Heart Association 2023, 12: e029077. PMID: 37301752, PMCID: PMC10356051, DOI: 10.1161/jaha.122.029077.Peer-Reviewed Original ResearchConceptsCarotid intima-media thicknessIntima-media thicknessCVH scoreCardiovascular healthLVM indexAbnormal sleep durationChildren's cardiovascular healthOverweight/obesityMin/wkWorse cardiovascular healthChild Cohort StudyM-mode echocardiographyAge/sexLower CVH scoreFollow-up (12- and 24-month) assessmentLipid scoreNormal BPCohort studyFasting GlucosePrimordial preventionNicotine exposureVentricular massPhysical activitySleep durationUS population
2021
Predictors of non-alcoholic fatty liver disease in children
Li M, Shu W, Zunong J, Amaerjiang N, Xiao H, Li D, Vermund SH, Hu Y. Predictors of non-alcoholic fatty liver disease in children. Pediatric Research 2021, 92: 322-330. PMID: 34580427, DOI: 10.1038/s41390-021-01754-6.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseasePediatric non-alcoholic fatty liver diseaseAbdominal obesity indicatorsFatty liver diseaseBody composition indicatorsLiver diseaseObesity indicatorsDiscriminative performancePopulation-based child cohortClinical Trials RegistryOptimal screening toolComposition indicatorsCurve valuesTrials RegistryLiver damageWeight managementChild CohortAnthropometric indicatorsEarly identificationLogistic regressionEndocrine indicatorsScreening toolDiseaseSpearman correlationCharacteristic curve
2020
Prevalence of HIV, HCV and HBV in Central Asia and the Caucasus: A systematic review
Davlidova S, Haley-Johnson Z, Nyhan K, Farooq A, Vermund SH, Ali S. Prevalence of HIV, HCV and HBV in Central Asia and the Caucasus: A systematic review. International Journal Of Infectious Diseases 2020, 104: 510-525. PMID: 33385583, PMCID: PMC11094609, DOI: 10.1016/j.ijid.2020.12.068.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusHepatitis B virusHepatitis C virusPrevalence of HIVHigh prevalenceSystematic reviewSubstantial public health threatHigh-risk groupHigh-risk populationNational surveillance reportsPublic health threatHBV prevalenceHCV prevalenceHIV prevalenceImmunodeficiency virusC virusLanguage restrictionsB virusPrevalenceSurveillance reportsHealth threatVirusPublication datePWIDEMBASEHIV Seroconversion and Types of Relationships Among Men Who Have Sex With Men: A Cohort Study in China.
Sun X, Wang C, Zhao K, Zhang L, Li M, Sun D, Shu W, Ruan Y, Zhang J, Vermund SH, Li D, Hu Y. HIV Seroconversion and Types of Relationships Among Men Who Have Sex With Men: A Cohort Study in China. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2020, 83: 365-372. PMID: 31913999, PMCID: PMC7055498, DOI: 10.1097/qai.0000000000002264.Peer-Reviewed Original ResearchMeSH KeywordsChinaCohort StudiesHIV InfectionsHIV SeropositivityHomosexuality, MaleHumansMaleRisk FactorsSafe SexUnsafe SexConceptsHIV seroconversionSeroconversion riskHIV seroconversion ratesHIV seroconversion riskMultivariable Cox regressionHIV-negative menIncident HIV infectionRegular sexual partnersRelative excess riskUnprotected anal sexSexual behaviorLast sexual encounterUnsafe sexual behaviorSafer sex educationSeroconversion ratesCohort studyHIV infectionRisky sexual behaviorHIV statusCox regressionExcess riskRisk factorsRegular partnersLow educational attainmentCasual partners
2019
Interventions to improve the HIV continuum of care in China
Zhang X, Wang N, Vermund SH, Zou H, Li X, Zhang F, Qian HZ. Interventions to improve the HIV continuum of care in China. Current HIV/AIDS Reports 2019, 16: 448-457. PMID: 31776975, PMCID: PMC10767704, DOI: 10.1007/s11904-019-00469-y.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyHIV continuumHIV epidemicPublic health intervention programsFree ART programHIV sexual transmissionHIV testing campaignsFormer plasma donorsPurpose of ReviewToHealth intervention programsTwo-thirdsViral suppressionHeterosexual transmissionPediatric mortalitySexual transmissionRisk groupsMore infectionsPlasma donorsRecent FindingsTheIntervention programsYoung menCareHIVHeterosexual menLower ratesSuboptimal Recent and Regular HIV Testing Among Black Men Who Have Sex With Men in the United States: Implications From a Meta-Analysis.
Liu Y, Silenzio VMB, Nash R, Luther P, Bauermeister J, Vermund SH, Zhang C. Suboptimal Recent and Regular HIV Testing Among Black Men Who Have Sex With Men in the United States: Implications From a Meta-Analysis. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2019, 81: 125-133. PMID: 30844996, PMCID: PMC6956840, DOI: 10.1097/qai.0000000000002013.Peer-Reviewed Original ResearchConceptsHIV testing prevalenceRegular HIV testingTesting prevalenceHIV testingDerSimonian-Laird random-effects modelContinuum of HIVHIV testing effortsHIV testing patternsFrequent HIV testingIllicit drug useRandom-effects modelMeta-regression analysisBlack menWeb of ScienceLow annual incomeEgger's testReceptive sexPRISMA guidelinesFunnel plotAlcohol consumptionDrug useIndependent investigatorsMeta-AnalysisPublication biasYounger age
2018
Surveillance of Maternal Syphilis in China: Pregnancy Outcomes and Determinants of Congenital Syphilis
Zhang X, Yu Y, Yang H, Xu H, Vermund SH, Liu K. Surveillance of Maternal Syphilis in China: Pregnancy Outcomes and Determinants of Congenital Syphilis. Medical Science Monitor 2018, 24: 7727-7735. PMID: 30370903, PMCID: PMC6216479, DOI: 10.12659/msm.910216.Peer-Reviewed Original ResearchConceptsAdverse pregnancy outcomesPregnancy outcomesCongenital syphilisPregnant womenFirst antenatal care visitEligible pregnant womenPrevention of motherAntenatal care visitsIndependent risk factorMultivariable regression analysisLogistic regression analysisRegression analysisChild transmissionMaternal syphilisAntenatal careCare visitsNeonatal asphyxiaNeonatal deathFirst trimesterRisk womenAntibody titersAntenatal testingEpidemiological characteristicsRisk factorsSyphilis diagnosisHIV-1 Transmission Clustering and Phylodynamics Highlight the Important Role of Young Men Who Have Sex with Men
Dennis AM, Volz E, Frost A, Hossain M, Poon AFY, Rebeiro P, Vermund SH, Sterling TR, Kalish ML. HIV-1 Transmission Clustering and Phylodynamics Highlight the Important Role of Young Men Who Have Sex with Men. AIDS Research And Human Retroviruses 2018, 34: 879-888. PMID: 30027754, PMCID: PMC6204570, DOI: 10.1089/aid.2018.0039.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsCluster AnalysisCross-Sectional StudiesFemaleGenotypeHIV InfectionsHIV-1Homosexuality, MaleHumansMaleMiddle AgedMolecular EpidemiologyPhylogenyPol Gene Products, Human Immunodeficiency VirusRetrospective StudiesRisk FactorsRNA, ViralSequence Analysis, DNATennesseeYoung AdultConceptsYoung MSMTransmission clustersHIV-1 pol sequencesTransmission riskComprehensive Care ClinicHIV transmission patternsVanderbilt Comprehensive Care ClinicYears of ageHIV molecular epidemiologyCross-sectional analysisHigh transmission riskClinical factorsCare clinicsRisk ratioClinical dataImportance of interventionsMSM riskPol sequencesTransmission clusteringYounger ageRisk behaviorsLogistic regressionMolecular epidemiologyMSMYoung menRisk Prediction Score for HIV Infection: Development and Internal Validation with Cross-Sectional Data from Men Who Have Sex with Men in China
Yin L, Zhao Y, Peratikos MB, Song L, Zhang X, Xin R, Sun Z, Xu Y, Zhang L, Hu Y, Hao C, Ruan Y, Shao Y, Vermund SH, Qian HZ. Risk Prediction Score for HIV Infection: Development and Internal Validation with Cross-Sectional Data from Men Who Have Sex with Men in China. AIDS And Behavior 2018, 22: 2267-2276. PMID: 29786768, PMCID: PMC7024582, DOI: 10.1007/s10461-018-2129-y.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAlcohol DrinkingChinaCondomsCross-Sectional StudiesHIV InfectionsHomosexuality, MaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisPrevalenceRisk AssessmentRisk FactorsRisk-TakingSafe SexSexual and Gender MinoritiesSexual BehaviorSexual PartnersSurveys and QuestionnairesSyphilisUnsafe SexYoung AdultConceptsHIV infectionRisk scoreHuman immunodeficiency virus (HIV) riskMultivariable logistic regression modelingBootstrap-corrected C-indexMultiple male sexual partnersValid risk scoreVaccine clinical trialsHigh-risk MSMHigh-risk personsRisk prediction scoreReceptive anal intercourseReceptive anal sexInconsistent condom useMale sexual partnersHIV prevention programmingLogistic regression modelingDrug/alcohol addictionHIV acquisitionRisk reduction programsSyphilis infectionHIV prevalenceClinical trialsC-indexIllegal drug useSevere outcomes associated with respiratory viruses in newborns and infants: a prospective viral surveillance study in Jordan
Khuri-Bulos N, Lawrence L, Piya B, Wang L, Fonnesbeck C, Faouri S, Shehabi A, Vermund SH, Williams JV, Halasa NB. Severe outcomes associated with respiratory viruses in newborns and infants: a prospective viral surveillance study in Jordan. BMJ Open 2018, 8: e021898. PMID: 29780032, PMCID: PMC5961648, DOI: 10.1136/bmjopen-2018-021898.Peer-Reviewed Original ResearchMeSH KeywordsAdenoviridaeAntiviral AgentsFemaleHumansInfantIntensive Care UnitsJordanLength of StayMaleOxygen Inhalation TherapyPalivizumabParainfluenza Virus 1, HumanProspective StudiesRespiratory Syncytial Virus InfectionsRespiratory Syncytial Virus VaccinesRespiratory Syncytial Virus, HumanRespiratory Tract InfectionsRhinovirusRisk FactorsConceptsLonger LOSLength of stayAcute respiratory infectionsIntensive care unitRespiratory syncytial virusOxygen therapyMechanical ventilationHospitalisation ratesICU admissionIllness severityRespiratory virusesMedical conditionsExtended breast feedingRSV vaccine developmentProspective cohort studyUnderlying medical conditionsChemotherapy-associated neutropeniaHuman parainfluenza virusesYears of ageCohort studyRespiratory symptomsBreast feedingRespiratory infectionsCare unitSyncytial virus
2017
HIV testing and sexual risks among migrant men who have sex with men: findings from a large cross-sectional study in Beijing, China
Liu Y, Vermund SH, Ruan Y, Liu H, Zhang C, Yin L, Shao Y, Qian HZ. HIV testing and sexual risks among migrant men who have sex with men: findings from a large cross-sectional study in Beijing, China. AIDS Care 2017, 30: 86-94. PMID: 28944685, PMCID: PMC6088860, DOI: 10.1080/09540121.2017.1381331.Peer-Reviewed Original ResearchConceptsLifetime male sexual partnersCondomless receptive anal sexHIV testingMigrant MSMHIV perceptionAnal sexHIV/syphilis infectionOlder ageLarge cross-sectional studyHIV/STI riskLikelihood of syphilisHIV/syphilisInsertive anal sexReceptive anal sexCross-sectional studyMale sexual partnersSyphilis infectionHIV transmissionLocal MSMSTI riskChinese MSMLower oddsEpidemiological studiesSexual partnersRisk profileMonitoring Anesthesia Care Delivery and Perioperative Mortality in Kenya Utilizing a Provider-driven Novel Data Collection Tool
Sileshi B, Newton MW, Kiptanui J, Shotwell MS, Wanderer JP, Mungai M, Scherdin J, Harris PA, Vermund SH, Sandberg WS, McEvoy MD. Monitoring Anesthesia Care Delivery and Perioperative Mortality in Kenya Utilizing a Provider-driven Novel Data Collection Tool. Anesthesiology 2017, 127: 250-271. PMID: 28657959, PMCID: PMC5519082, DOI: 10.1097/aln.0000000000001713.Peer-Reviewed Original ResearchConceptsPerioperative dataPerioperative mortality rateTertiary referral hospitalMortality rate differencesAnesthesia care deliveryLogistic regression modelsMiddle-income settingsPerioperative mortalityCesarean deliveryEmergency surgeryMiddle-income countriesPerioperative careReferral hospitalSurgery typeSingle centerProcedure typeGeneral surgeryHigh riskMortality rateCare deliveryMortalityData collection periodData collection toolSurgeryRegression modelsEffects of depression and anxiety on antiretroviral therapy adherence among newly diagnosed HIV-infected Chinese MSM
Tao J, Qian HZ, Kipp AM, Ruan Y, Shepherd BE, Amico KR, Shao Y, Lu H, Vermund SH. Effects of depression and anxiety on antiretroviral therapy adherence among newly diagnosed HIV-infected Chinese MSM. AIDS 2017, 31: 401-406. PMID: 27677168, PMCID: PMC5233466, DOI: 10.1097/qad.0000000000001287.Peer-Reviewed Original ResearchConceptsImperfect ART adherenceEffect of depressionART adherenceAntiretroviral therapyHIV infectionChinese MSMHIV treatment outcomesAntiretroviral therapy adherenceEnd of studyMixed-effects logistic regressionHIV diagnosisOne-unit increaseProspective studyTherapy adherenceHospital AnxietyRisk factorsTreatment outcomesDepression ScaleSignificant associationIntensive interventionLogistic regressionMSMAnxiety scoresAdherenceInfectionSubsequent Sexual Risks Among Men Who Have Sex with Men May Differ by Sex of First Partner and Age at Sexual Debut: A Cross-Sectional Study in Beijing, China
Liu Y, Qian HZ, Amico KR, Liu H, Yin L, Ruan Y, Shao Y, Zhang C, Vermund SH. Subsequent Sexual Risks Among Men Who Have Sex with Men May Differ by Sex of First Partner and Age at Sexual Debut: A Cross-Sectional Study in Beijing, China. AIDS And Behavior 2017, 21: 2913-2923. PMID: 28110474, PMCID: PMC5522364, DOI: 10.1007/s10461-017-1677-x.Peer-Reviewed Original ResearchConceptsSexual debutSexual riskSyphilis riskAnal sexFirst sexLifetime female partnersLifetime male partnersHIV/syphilisInsertive anal sexReceptive anal sexCross-sectional studyRecent vaginal sexHIV riskChinese MSMMSM riskSubsequent sexual riskVaginal sexMale partnersFemale partnersSexMenWomenRiskSyphilisAge
2016
Commercial sex and risk of HIV, syphilis, and herpes simplex virus-2 among men who have sex with men in six Chinese cities
Zheng C, Xu JJ, Hu QH, Yu YQ, Chu ZX, Zhang J, Han XX, Lu L, Wang Z, Fu JH, Chen X, Yan HJ, Jiang YJ, Geng WQ, Vermund SH, Qian HZ, Shang H. Commercial sex and risk of HIV, syphilis, and herpes simplex virus-2 among men who have sex with men in six Chinese cities. BMC Infectious Diseases 2016, 16: 765. PMID: 28003032, PMCID: PMC5178086, DOI: 10.1186/s12879-016-2130-x.Peer-Reviewed Original ResearchConceptsHIV/STIsHigh prevalenceHigh riskSex partnersHIV/STI surveillanceSimplex virus type 2HSV-2 infectionHIV/STISubgroups of MSMSimplex virus 2Male sex partnersCommercial sexRisk of HIVUnprotected anal intercourseVirus type 2Cross-sectional surveyHIV prevalenceSTI surveillanceHSV-2Overall prevalenceAnal intercourseHIVType 2Serological testsGreater riskSubstance use and HIV-risk behaviors among HIV-positive men who have sex with men in China: repeated measures in a cohort study design
Zhang C, Liu Y, Sun X, Wang J, Lu HY, He X, Zhang H, Ruan YH, Shao Y, Vermund SH, Qian HZ. Substance use and HIV-risk behaviors among HIV-positive men who have sex with men in China: repeated measures in a cohort study design. AIDS Care 2016, 29: 644-653. PMID: 27832699, PMCID: PMC5350012, DOI: 10.1080/09540121.2016.1255709.Peer-Reviewed Original ResearchConceptsHIV risk behaviorsCohort study designSubstance useStudy designHIV-positive MSMHIV-positive menGeneralized Estimating Equation modelsFemale sex partnersRapid HIV transmissionMale sexual partnersRigorous study designsSexual risk behaviorsCurrent studySeronegative counterpartsSeropositive menSeropositive partnersHIV transmissionMean agePotential confoundersRisk factorsHigh riskRisk populationsSex partnersUnprotected sexRisk behaviorsSexual Behaviors Linked to Drug and Alcohol Use Among Men Who Have Sex With Men in China
Zhang C, Qian HZ, Yin L, Liu Y, Strauss SM, Ruan Y, Shao Y, Lu H, Vermund SH. Sexual Behaviors Linked to Drug and Alcohol Use Among Men Who Have Sex With Men in China. Substance Use & Misuse 2016, 51: 1821-1830. PMID: 27608264, PMCID: PMC5423713, DOI: 10.1080/10826084.2016.1197264.Peer-Reviewed Original ResearchConceptsAlcohol useHigher oddsAlcohol consumptionSexual behaviorDrug useHigh-risk sexual behaviorFemale partnersHistory of alcoholSexual risk behaviorsHigh-risk behaviorsEffects of drugsSelf-administered questionnaireSyphilis infectionHIV infectionSyphilis prevalenceMean ageSyphilis testingClinical trialsHIV epidemicHIV interventionsBlood samplesHIVHan ethnicityRisk behaviorsMSMFrequent HIV Testing
Liu Y, Qian HZ, Ruan Y, Wu P, Osborn CY, Jia Y, Yin L, Lu H, He X, Shao Y, Vermund SH. Frequent HIV Testing. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2016, 72: 452-461. PMID: 27003496, PMCID: PMC4925192, DOI: 10.1097/qai.0000000000001001.Peer-Reviewed Original ResearchConceptsMultivariable logistic regression analysisCurrent HIV infectionHIV incidence reductionHIV testing historyPropensity score adjustmentCubic spline modelingBorderline significant trendLogistic regression analysisHigher testing ratesHIV infectionHIV serostatusPrevious HIVHIV epidemicBeijing MSMTesting ratesScore adjustmentIncidence reductionTesting historyHIVInfection statusBehavioral factorsRegression analysisMSMOddsMenAssociations of current marital status and living arrangements with HIV and syphilis risk: findings from a community-based sample of men who have sex with men in China
Liu Y, Li D, Vermund SH, Zhang C, Ruan Y, Yin L, Liu H, Amico KR, Shao Y, Qian HZ. Associations of current marital status and living arrangements with HIV and syphilis risk: findings from a community-based sample of men who have sex with men in China. AIDS Care 2016, 28: 1461-1466. PMID: 27236988, PMCID: PMC5344671, DOI: 10.1080/09540121.2016.1189502.Peer-Reviewed Original ResearchConceptsMale sex partnersSingle MSMSyphilis riskMarital statusCurrent marital statusSex partnersMultivariable logistic regression modelingReceptive anal intercourseCondomless vaginal sexCross-sectional studyLogistic regression modelingCommunity-based sampleHIV-positiveChinese MSMAnal intercourseLower oddsChinese menMarried MSMVaginal sexRisk reduction strategiesSexual partnersInfection statusMSMHIVInfection prevalenceLower HIV Risk Among Circumcised Men Who Have Sex With Men in China
Qian HZ, Ruan Y, Liu Y, Milam DF, Spiegel HM, Yin L, Li D, Shepherd BE, Shao Y, Vermund SH. Lower HIV Risk Among Circumcised Men Who Have Sex With Men in China. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2016, 71: 444-451. PMID: 26413852, PMCID: PMC4767598, DOI: 10.1097/qai.0000000000000856.Peer-Reviewed Original ResearchConceptsLower oddsHIV infectionGenital examinationMale circumcisionVoluntary medical male circumcisionLifetime male sexual partnersHIV heterosexual transmissionMale sexual transmissionLow HIV riskInsertive anal sexInsertive anal intercourseMedical male circumcisionMale sexual partnersAnal sex rolesUncircumcised menCircumcision statusHeterosexual transmissionSexual transmissionInsertive sexClinical trialsHIV riskCircumcision ratesSyphilis riskAnal intercourseLower risk