2022
Projected outcomes of universal testing and treatment in a generalised HIV epidemic in Zambia and South Africa (the HPTN 071 [PopART] trial): a modelling study
Probert W, Sauter R, Pickles M, Cori A, Bell-Mandla N, Bwalya J, Abeler-Dörner L, Bock P, Donnell D, Floyd S, Macleod D, Piwowar-Manning E, Skalland T, Shanaube K, Wilson E, Yang B, Ayles H, Fidler S, Hayes R, Fraser C, Team H, Hayes R, Fidler S, Beyers N, Ayles H, Bock P, El-Sadr W, Cohen M, Eshleman S, Agyei Y, Piwowar-Manning E, Bond V, Hoddinott G, Donnell D, Floyd S, Wilson E, Emel L, Noble H, Macleod D, Burns D, Fraser C, Cori A, Sista N, Griffith S, Moore A, Headen T, White R, Miller E, Hargreaves J, Hauck K, Thomas R, Limbada M, Bwalya J, Pickles M, Sabapathy K, Schaap, Dunbar R, Shanaube K, Yang B, Simwinga M, Smith P, Vermund S, Mandla N, Makola N, van Deventer A, James A, Jennings K, Kruger J, Phiri M, Kosloff B, Mwenge L, Kanema S, Sauter R, Probert W, Kumar R, Sakala E, Silumesi A, Skalland T, Yuhas K. Projected outcomes of universal testing and treatment in a generalised HIV epidemic in Zambia and South Africa (the HPTN 071 [PopART] trial): a modelling study. The Lancet HIV 2022, 9: e771-e780. PMID: 36332654, PMCID: PMC9646978, DOI: 10.1016/s2352-3018(22)00259-4.Peer-Reviewed Original ResearchConceptsStandard of careHome-based testingCluster-randomised trialHigh-prevalence communitiesHIV incidenceHIV epidemicNational guidelinesNational InstituteUniversal testingHIV care cascadeAntiretroviral therapy uptakeUS President's Emergency PlanGeneralised HIV epidemicPresident's Emergency PlanPopART interventionCare cascadeART eligibilityArm BTherapy uptakeTrial interventionTrial dataInfectious diseasesAIDS ReliefIntervention impactDrug abuse
2021
Power of Big Data in ending HIV
Olatosi B, Vermund SH, Li X. Power of Big Data in ending HIV. AIDS 2021, 35: s1-s5. PMID: 33867484, PMCID: PMC10950305, DOI: 10.1097/qad.0000000000002888.Peer-Reviewed Original Research
2019
Interventions to improve the HIV continuum of care in China
Zhang X, Wang N, Vermund SH, Zou H, Li X, Zhang F, Qian HZ. Interventions to improve the HIV continuum of care in China. Current HIV/AIDS Reports 2019, 16: 448-457. PMID: 31776975, PMCID: PMC10767704, DOI: 10.1007/s11904-019-00469-y.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyHIV continuumHIV epidemicPublic health intervention programsFree ART programHIV sexual transmissionHIV testing campaignsFormer plasma donorsPurpose of ReviewToHealth intervention programsTwo-thirdsViral suppressionHeterosexual transmissionPediatric mortalitySexual transmissionRisk groupsMore infectionsPlasma donorsRecent FindingsTheIntervention programsYoung menCareHIVHeterosexual menLower ratesTreatment as Prevention: Concepts and Challenges for Reducing HIV Incidence
Brault MA, Spiegelman D, Hargreaves J, Nash D, Vermund SH. Treatment as Prevention: Concepts and Challenges for Reducing HIV Incidence. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2019, 82: s104-s112. PMID: 31658196, PMCID: PMC6820703, DOI: 10.1097/qai.0000000000002168.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyHIV transmissionHIV plasma loadReducing HIV IncidenceHIV prevention trialsCommunity-level interventionsDeployable vaccineViral suppressionHIV testingHIV incidencePrevention trialsUninfected personsChronic conditionsHIV investmentsEarly treatmentTreat strategySexual partnersViral expressionTransmission riskHIVTrialsTreatmentInconsistent findingsPreventionSaharan Africa
2017
Control of HIV epidemic: improve access to testing and ART
Vermund SH. Control of HIV epidemic: improve access to testing and ART. The Lancet HIV 2017, 4: e533-e534. PMID: 28867268, PMCID: PMC10950070, DOI: 10.1016/s2352-3018(17)30166-2.Peer-Reviewed Original Research
2014
Modeling the Impact on HIV Incidence of Combination Prevention Strategies among Men Who Have Sex with Men in Beijing, China
Lou J, Blevins M, Ruan Y, Vermund SH, Tang S, Webb GF, Shepherd BE, He X, Lu H, Shao Y, Qian HZ. Modeling the Impact on HIV Incidence of Combination Prevention Strategies among Men Who Have Sex with Men in Beijing, China. PLOS ONE 2014, 9: e90985. PMID: 24626165, PMCID: PMC3953201, DOI: 10.1371/journal.pone.0090985.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyHIV epidemicCondom useHIV prevalenceART coverageCombination prevention strategiesHIV/AIDSHIV testingHIV incidenceCombination interventionsBeijing MSMPrevention strategiesPrevalence estimatesPrevalenceEpidemic expansionMenInterventionEpidemicIncidenceBasic reproduction numberPrevention scenariosCurrent coverageSexReproduction numberIntervention levels
2013
HIV/AIDS trends in China
Vermund SH. HIV/AIDS trends in China. The Lancet Infectious Diseases 2013, 13: 912-914. PMID: 24107262, PMCID: PMC7129631, DOI: 10.1016/s1473-3099(13)70285-8.Peer-Reviewed Original ResearchCan Combination Prevention Strategies Reduce HIV Transmission in Generalized Epidemic Settings in Africa? The HPTN 071 (PopART) Study Plan in South Africa and Zambia
Vermund SH, Fidler SJ, Ayles H, Beyers N, Hayes RJ. Can Combination Prevention Strategies Reduce HIV Transmission in Generalized Epidemic Settings in Africa? The HPTN 071 (PopART) Study Plan in South Africa and Zambia. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2013, 63: s221-s227. PMID: 23764639, PMCID: PMC3739051, DOI: 10.1097/qai.0b013e318299c3f4.Peer-Reviewed Original ResearchConceptsHIV Prevention Trials NetworkHPTN 071 (PopART) studyHPTN 071HIV incidenceHIV transmissionHome-based HIV testingVoluntary medical male circumcisionGeneralized epidemic settingsLinkage of HIVUniversal antiretroviral therapyChild HIV transmissionPrevention of motherHIV viral loadCommunity health workersMedical male circumcisionCommunity-randomized trialIntervention strategiesCombination prevention strategiesAntiretroviral therapyHIV acquisitionSeropositive personsTuberculosis servicesHIV testingViral loadTuberculosis transmission
2012
The HIV Epidemic: High-Income Countries
Vermund SH, Leigh-Brown AJ. The HIV Epidemic: High-Income Countries. Cold Spring Harbor Perspectives In Medicine 2012, 2: a007195. PMID: 22553497, PMCID: PMC3331688, DOI: 10.1101/cshperspect.a007195.Peer-Reviewed Original ResearchConceptsInjection drug useHIV epidemicDrug useNeedle/syringe sharingReceptive anal intercourseDifferent risk groupsRecent explosive epidemicsAntiretroviral therapyChild transmissionSyringe sharingAffected subgroupRisk groupsAnal intercourseVaginal intercourseHIV vulnerabilityExplosive epidemicsDiagnostic screeningEpidemicIncome countriesIntercourseUnited StatesSpecific strainsHigh-income nationsHIVTherapy