2000
The Use Of Isolated Limb Perfusion To Manage Recurrent Malignant Melanoma
Ma D, Ariyan S. The Use Of Isolated Limb Perfusion To Manage Recurrent Malignant Melanoma. Clinics In Plastic Surgery 2000, 27: 441-450. PMID: 10941564, DOI: 10.1016/s0094-1298(20)32739-5.Peer-Reviewed Original ResearchConceptsRecurrent malignant melanomaMalignant melanomaLimb perfusionTumor necrosis factor alphaRecurrent metastatic diseaseIsolated limb perfusionNecrosis factor alphaList of drugsHyperthermic ILPRecurrent diseaseMetastatic diseaseTumor loadLimb functionClinical trialsSurgical techniqueFactor alphaWound hygieneChemotherapeutic agentsMelanomaPerfusionDiseaseExtremitiesTreatmentHyperthermicTrials
1998
Safety and efficacy of isolated perfusion of extremities for recurrent tumor in elderly patients
Ariyan S, Poo W. Safety and efficacy of isolated perfusion of extremities for recurrent tumor in elderly patients. Surgery 1998, 123: 335-343. PMID: 9526527, DOI: 10.1016/s0039-6060(98)70188-6.Peer-Reviewed Original ResearchConceptsElderly patientsYounger patientsIsolated perfusionMeaningful disease controlRegional isolated perfusionEvidence of diseaseHigh-dose chemotherapySeries of patientsIsolated limb perfusionMajor surgical proceduresNumber of patientsDisease-free controlsYears of ageSalvage of limbsSignificant palliationThird perfusionAggressive treatmentDose chemotherapyOlder patientsRecurrent diseaseSurvival benefitTransit diseaseSerious complicationsRecurrent tumorsLimb perfusion
1997
Regional Isolated Perfusion of Extremities for Melanoma: A 20-Year Experience with Drugs Other than L-Phenylalanine Mustard
Ariyan S, Poo W, Bolognia J. Regional Isolated Perfusion of Extremities for Melanoma: A 20-Year Experience with Drugs Other than L-Phenylalanine Mustard. Plastic & Reconstructive Surgery 1997, 99: 1023-1029. PMID: 9091898, DOI: 10.1097/00006534-199704000-00016.Peer-Reviewed Original ResearchConceptsL-phenylalanine mustardRegional isolated perfusionIsolated limb perfusionIsolated perfusionLimb perfusionUpper extremityLower extremitiesTherapeutic isolated limb perfusionNonfatal pulmonary embolusRegional treatment modalityEvidence of diseaseHigh-dose chemotherapyHigh-risk melanomaNumber of patientsDifficult management problemDisease-free controlsTechnique of perfusionLimb recurrenceMeaningful palliationRepeat perfusionsAggressive treatmentPulmonary emboliDose chemotherapyRecurrent melanomaSerious complications
1982
Granulomatous lymphangitis. A complication of intralymphatic immunotherapy with methanol extraction residue of BCG (MER)
Kirkwood J, Ariyan S, Nordlund J, Forget B. Granulomatous lymphangitis. A complication of intralymphatic immunotherapy with methanol extraction residue of BCG (MER). Cancer 1982, 50: 1299-1303. PMID: 7104973, DOI: 10.1002/1097-0142(19821001)50:7<1299::aid-cncr2820500714>3.0.co;2-#.Peer-Reviewed Original ResearchConceptsBacille Calmette-GuerinMethanol extraction residueCalmette-GuerinThick primary melanomasDefinitive surgical excisionAdjuvant therapyIntralymphatic immunotherapyRegional metastasesRecurrent melanomaRegional nodalClinical presentationSurgical excisionAdjuvant agentLocal instillationIntralymphatic injectionsPrimary tumorPrimary melanomaAntitumor effectsGranulomatous lymphangitisExperimental animalsSubstantial riskComplicationsThick primariesImmunotherapyTherapy