2012
Quantifying selection in high-throughput Immunoglobulin sequencing datasets (58.4)
Yaari G, Uduman M, Kleinstein S. Quantifying selection in high-throughput Immunoglobulin sequencing datasets (58.4). The Journal Of Immunology 2012, 188: 58.4-58.4. DOI: 10.4049/jimmunol.188.supp.58.4.Peer-Reviewed Original Research
2006
Mutation parameters from DNA sequence data using graph theoretic measures on lineage trees
Magori-Cohen R, Louzoun Y, Kleinstein SH. Mutation parameters from DNA sequence data using graph theoretic measures on lineage trees. Bioinformatics 2006, 22: e332-e340. PMID: 16873490, DOI: 10.1093/bioinformatics/btl239.Peer-Reviewed Original ResearchConceptsLineage treesDNA sequencesDNA sequence dataSomatic hypermutationMaximum likelihood analysisTree shapeBioinformatics methodsSequence dataLethal mutationsMutation rateNumber of generationsLikelihood analysisMutation parametersB cellsSynthetic treeClonal expansionTreesSequenceMutationsHypermutationAffinity maturationCellsImportant linkClonesUnexpected locations