Practical guidelines for B-cell receptor repertoire sequencing analysis
Yaari G, Kleinstein SH. Practical guidelines for B-cell receptor repertoire sequencing analysis. Genome Medicine 2015, 7: 121. PMID: 26589402, PMCID: PMC4654805, DOI: 10.1186/s13073-015-0243-2.Peer-Reviewed Original ResearchConceptsSequencing analysisHigh-throughput sequencingRaw sequencing readsRepertoire sequencing dataUnique molecular identifiersMillions of sequencesPopulation structureAutomated analysis of high-throughput B-cell sequencing data reveals a high frequency of novel immunoglobulin V gene segment alleles
Gadala-Maria D, Yaari G, Uduman M, Kleinstein SH. Automated analysis of high-throughput B-cell sequencing data reveals a high frequency of novel immunoglobulin V gene segment alleles. Proceedings Of The National Academy Of Sciences Of The United States Of America 2015, 112: e862-e870. PMID: 25675496, PMCID: PMC4345584, DOI: 10.1073/pnas.1417683112.Peer-Reviewed Original Research