2024
Inferring B Cell Phylogenies from Paired H and L Chain BCR Sequences with Dowser.
Jensen C, Sumner J, Kleinstein S, Hoehn K. Inferring B Cell Phylogenies from Paired H and L Chain BCR Sequences with Dowser. The Journal Of Immunology 2024, 212: 1579-1588. PMID: 38557795, PMCID: PMC11073909, DOI: 10.4049/jimmunol.2300851.Peer-Reviewed Original ResearchMeSH KeywordsB-LymphocytesHumansImmunoglobulin Heavy ChainsImmunoglobulin Light ChainsMutationPhylogenyReceptors, Antigen, B-CellSingle-Cell AnalysisConceptsPhylogenetic treeL chainsBranch lengthsBCR sequencesTree-building methodsSingle-cell sequencing dataHistory of mutationsSingle-cell sequencingPhylogenetic methodsSequence dataSequencing technologiesL chain sequencesTree accuracyEvolutionary processSingle-cellPhylogenyImmune responseSomatic hypermutationSequenceClonesMutationsB cell clonesHuman immune responseTreesBCR
2019
Cutting Edge: Ig H Chains Are Sufficient to Determine Most B Cell Clonal Relationships.
Zhou JQ, Kleinstein SH. Cutting Edge: Ig H Chains Are Sufficient to Determine Most B Cell Clonal Relationships. The Journal Of Immunology 2019, 203: 1687-1692. PMID: 31484734, PMCID: PMC6865802, DOI: 10.4049/jimmunol.1900666.Peer-Reviewed Original Research