2020
Considerations in Management of Acute Otitis Media in the COVID-19 Era
Mohan S, Workman A, Barshak M, Welling D, Abdul-Aziz D. Considerations in Management of Acute Otitis Media in the COVID-19 Era. Annals Of Otology Rhinology & Laryngology 2020, 130: 520-527. PMID: 32911957, DOI: 10.1177/0003489420958443.Peer-Reviewed Original ResearchConceptsMiddle ear fluidAcute otitis mediaComplicated acute otitis mediaEar fluidOtitis mediaSARS-CoV-2 infectionSARS-CoV-2Management of Acute Otitis MediaFacial paralysisPCR of nasopharyngeal swabClinical management of patientsPositive viral PCRTreated with myringotomyManagement of patientsBlue light filterCadaveric temporal bonesOtologic findingsSystemic antibioticsEar diseaseNegative PCRAcute infectionClinical managementOtologic proceduresProlonged close contactNasopharyngeal swabsToward an Automatic System for Computer-Aided Assessment in Facial Palsy
Guarin D, Yunusova Y, Taati B, Dusseldorp J, Mohan S, Tavares J, van Veen M, Fortier E, Hadlock T, Jowett N. Toward an Automatic System for Computer-Aided Assessment in Facial Palsy. Facial Plastic Surgery & Aesthetic Medicine 2020, 22: 42-49. PMID: 32053425, PMCID: PMC7362997, DOI: 10.1089/fpsam.2019.29000.gua.Peer-Reviewed Original ResearchConceptsFacial landmark localizationLandmark localizationMachine learningML algorithmsFacial landmarksAutomatic systemComputer-aided diagnosis systemLocalization accuracyGraphical user interfaceCustom graphical user interfaceLandmark localization accuracyComputer-Aided AssessmentPoor localization accuracyUser interfaceDetection modelMore imagesDiagnosis systemML modelsAvailable algorithmsManual markingNovel ML algorithmsNovel ML modelsLarge databaseAlgorithm accuracyLocalization model
2019
Stain-Free Resolution of Unmyelinated Axons in Transgenic Mice Using Fluorescence Microscopy
Mohan S, Hernández I, Selig M, Shibata S, Jowett N. Stain-Free Resolution of Unmyelinated Axons in Transgenic Mice Using Fluorescence Microscopy. Journal Of Neuropathology & Experimental Neurology 2019, 78: 1178-1180. PMID: 31642916, PMCID: PMC7967843, DOI: 10.1093/jnen/nlz099.Peer-Reviewed Original ResearchHealth Utility Values as an Outcome Measure in Patients Undergoing Functional Septorhinoplasty
Gadkaree S, Fuller J, Justicz N, Weitzman R, Derakhshan A, Mohan S, Lindsay R. Health Utility Values as an Outcome Measure in Patients Undergoing Functional Septorhinoplasty. Facial Plastic Surgery & Aesthetic Medicine 2019, 21: 381-386. PMID: 31120515, PMCID: PMC6547223, DOI: 10.1001/jamafacial.2019.0234.Peer-Reviewed Original ResearchConceptsHealth utility valuesEQ-5D scoresOverall healthNasal obstructionMeasure health utility valuesFunctional septorhinoplastyEuroQol-5 DimensionsPopulation-based dataImprove overall healthPostoperative EQ-5D scoresEQ-5D questionnaireProspective cohort studyOutcome of septorhinoplastyChronic conditionsEQ-5D surveyEQ-5DUS populationChronic diseasesOutcome measuresCohort studyUtility valuesHealthSinus surgeryNasal surgeryFemale sexA Comparative Health Utility Value Analysis of Outcomes for Patients Following Septorhinoplasty With Previous Nasal Surgery
Gadkaree S, Fuller J, Justicz N, Derakhshan A, Mohan S, Yu P, Lindsay R. A Comparative Health Utility Value Analysis of Outcomes for Patients Following Septorhinoplasty With Previous Nasal Surgery. Facial Plastic Surgery & Aesthetic Medicine 2019, 21: 402-406. PMID: 31194223, PMCID: PMC6567843, DOI: 10.1001/jamafacial.2019.0176.Peer-Reviewed Original ResearchConceptsHealth utility valuesProspective cohort studyNasal surgerySingle-institution prospective cohort studyCohort studyFunctional rhinoplastyPredictors of outcomeHealth utilization outcomesEQ-5D scoresEQ-5D questionnaireAlar rim graftsAnalysis of outcomesCost-utility analysisSleep apneaNasal obstructionSurgical historyUtilization outcomesPrimary rhinoplastySurgical proceduresHealth statusMultivariate analysisSurgeryRim graftsOverall healthSpreader graftsAn Anatomic Variant of the Ansa Cervicalis Precluding Its Use as a Donor Nerve
Zhu A, Mohan S, Richmon J, Jowett N. An Anatomic Variant of the Ansa Cervicalis Precluding Its Use as a Donor Nerve. Annals Of Otology Rhinology & Laryngology 2019, 129: 78-81. PMID: 31510759, DOI: 10.1177/0003489419875975.Peer-Reviewed Original ResearchConceptsAnsa cervicalisAnatomic variantsVagus nerveParotid adenoid cystic carcinomaLeft vocal fold palsyCranial nerve repairFacial nerve resectionIpsilateral hypoglossal nerveRelevant anatomic variantsVocal fold palsyAdenoid cystic carcinomaInterposition repairDonor nerveNerve resectionSural nerveHypoglossal nerveInadvertent injuryNerve epineuriumCystic carcinomaGraft harvestNerve repairApparent morbidityNerveMuscle contractionCervicalis
2018
Fluorescent Reporter Mice for Nerve Guidance Conduit Assessment: A High‐Throughput in vivo Model
Mohan S, Hernández I, Wang W, Yin K, Sundback C, Wegst U, Jowett N. Fluorescent Reporter Mice for Nerve Guidance Conduit Assessment: A High‐Throughput in vivo Model. The Laryngoscope 2018, 128: e386-e392. PMID: 30098047, DOI: 10.1002/lary.27439.Peer-Reviewed Original ResearchConceptsHigh-throughput platformConduit performanceTissue processing stepsRobust axonal sproutingSciatic nerve transectionHigh throughputCryosection techniqueFluorescent reporter miceVivo mammalian modelsInterposition repairAxonal sproutingNerve transectionIsoflurane anesthesiaPeripheral neuronsAxonal ingrowthProcedure timeReporter miceNerve regenerationTransgenic miceVivo modelMiceMicroscopyVivo platformFluorescent proteinFluorescent microscopyLong-Term Outcomes of Free Gracilis Muscle Transfer for Smile Reanimation in Children
Greene J, Tavares J, Mohan S, Jowett N, Hadlock T. Long-Term Outcomes of Free Gracilis Muscle Transfer for Smile Reanimation in Children. The Journal Of Pediatrics 2018, 202: 279-284.e2. PMID: 30054167, DOI: 10.1016/j.jpeds.2018.06.043.Peer-Reviewed Original ResearchConceptsFree gracilis muscle transferFacial palsyGracilis muscle transferSmile excursionQuality of lifeMuscle transferPostoperative photographySmile reanimationFacial Clinimetric Evaluation (FaCE) surveyPatient-based instrumentLong-term outcomesCohort of childrenFacial nerve centerFacial symmetryPediatric patientsPostoperative qualityLife scoresTerm outcomesRetrospective analysisMassachusetts EyePalsySignificant improvementFacial impairmentPatientsFacial asymmetryOpioids and the Otolaryngologist: An Ambulatory Assessment
Mohan S, Bhattacharyya N. Opioids and the Otolaryngologist: An Ambulatory Assessment. Otolaryngology 2018, 159: 29-34. PMID: 29557264, DOI: 10.1177/0194599818765125.Peer-Reviewed Original ResearchConceptsOpioid prescriptionsOtolaryngology visitsOpioid prescribingCalendar trendsNational Ambulatory Medical Care SurveyAmbulatory Medical Care SurveyDesign Cross-sectional analysisOpioid medication prescribingOpioid prescription patternsChronic otitis mediaOpioid prescription ratesAmbulatory care settingsCross-sectional analysisOutpatient opioidsNational survey databasePrescription patternsNasal obstructionPrescription ratesMedication prescribingPostoperative careOtitis externaOtitis mediaCare SurveyOpioid epidemicCare settingsAssessment of Disease‐Specific and General Patient‐Reported Outcome Measures of Hearing Health
Mohan S, Corrales C, Yueh B, Shin J. Assessment of Disease‐Specific and General Patient‐Reported Outcome Measures of Hearing Health. Otolaryngology 2018, 158: 702-709. PMID: 29460681, DOI: 10.1177/0194599818757998.Peer-Reviewed Original ResearchConceptsPROMIS scoresTertiary care academic medical centerMental health summary scoresGlobal itemMental healthPhysical healthInner earProspective cohort dataDisease-specific assessmentsGeneral health statusHealth summary scoresComposite scoreItem scoresAcademic medical centerMean scoreChief complaintPROMIS instrumentsDisease-SpecificGeneral patientsHearing lossOutcome measuresMedical CenterMethods AdultsSummary scoresHealth status
2017
Modified approach for pediatric external cricopharyngeal myotomy
Mohan S, Bowe S, Hirner L, Zar-Kessler C, Hartnick C. Modified approach for pediatric external cricopharyngeal myotomy. International Journal Of Pediatric Otorhinolaryngology 2017, 105: 111-114. PMID: 29447795, DOI: 10.1016/j.ijporl.2017.12.019.Peer-Reviewed Original ResearchConceptsOpen cricopharyngeal myotomyCricopharyngeal myotomyCricopharyngeal achalasiaUpper esophageal sphincter relaxationPediatric cricopharyngeal achalasiaBotulinum toxin injectionEsophageal sphincter relaxationRecurrent laryngeal nerveBalloon dilationEsophageal perforationSphincter relaxationToxin injectionLaryngeal nerveOropharyngeal dysphagiaPosterior midlineImportant causeRisky procedureYoung malesAchalasiaMyotomyDysphagiaCricopharyngeusNervePathophysiologyAdjuvant radiotherapy is not supported in patients with verrucous carcinoma of the oral cavity
Mohan S, Pai S, Bhattacharyya N. Adjuvant radiotherapy is not supported in patients with verrucous carcinoma of the oral cavity. The Laryngoscope 2017, 127: 1334-1338. PMID: 28150306, PMCID: PMC7388729, DOI: 10.1002/lary.26443.Peer-Reviewed Original ResearchMeSH KeywordsAgedCarcinoma, Squamous CellCarcinoma, VerrucousCross-Sectional StudiesDisease-Free SurvivalFemaleHead and Neck NeoplasmsHumansKaplan-Meier EstimateMaleMiddle AgedMouthMouth NeoplasmsNeoplasm Recurrence, LocalRadiotherapy, AdjuvantSEER ProgramSquamous Cell Carcinoma of Head and NeckTreatment OutcomeConceptsAdjuvant radiation therapyDisease-specific survivalSquamous cell carcinomaVerrucous carcinomaRadiation therapyOverall survivalOral cavityVC patientsWorse OSCarcinoma patientsImproved overall survivalEnd Results (SEER) databaseKaplan-Meier survivalAdjuvant radiotherapySCC patientsLocal recurrenceResults databaseT stagePositive marginsSCC casesCell carcinomaPatientsSurgeryCarcinomaDifferent biology