2015
A protein interaction map of the LSU processome
McCann KL, Charette JM, Vincent NG, Baserga SJ. A protein interaction map of the LSU processome. Genes & Development 2015, 29: 862-875. PMID: 25877921, PMCID: PMC4403261, DOI: 10.1101/gad.256370.114.Peer-Reviewed Original ResearchConceptsLarge ribosomal subunitBiogenesis factorsRibosome biogenesis factorsTwo-hybrid assayProtein interaction mapsProtein-protein interactionsSystems biology approachInteractome mapHub proteinsBiology approachProcessomeProtein pairsRibosomal subunitInteraction mapCoordinated processConcerted actionCurrent knowledgeEukaryotesNOP4SubcomplexSubunitsProteinFourfold increaseMaturationAssembly
2014
Making Ribosomes: Pre-rRNA Transcription and Processing
McCann K, Baserga S. Making Ribosomes: Pre-rRNA Transcription and Processing. 2014, 217-232. DOI: 10.1007/978-3-319-05687-6_9.Peer-Reviewed Original Research
2012
The Box C/D sRNP dimeric architecture is conserved across Kingdom Archaea
Baserga S, Phipps K, Taylor D, Wang H. The Box C/D sRNP dimeric architecture is conserved across Kingdom Archaea. The FASEB Journal 2012, 26: 773.2-773.2. DOI: 10.1096/fasebj.26.1_supplement.773.2.Peer-Reviewed Original ResearchBox C/D sRNPDimeric architectureBox C/DRecent structural studiesSRNP assemblyArchaeal speciesArchaeal kingdomOligomeric architectureKingdom ArchaeaPyrococcus abyssiArchaeoglobus fulgidusMutational analysisSRNPSingle-particle reconstructionStructural determinantsArchaeaStructural studiesEukaryotesSRNAsFulgidusSolfataricusParticle reconstructionRNASpeciesMutations
2009
Electron microscopy reveals that archaeal box C/D sRNPs are di‐sRNPs
Bleichert F, Gagnon K, Brown B, Maxwell S, Unger V, Baserga S. Electron microscopy reveals that archaeal box C/D sRNPs are di‐sRNPs. The FASEB Journal 2009, 23: 661.2-661.2. DOI: 10.1096/fasebj.23.1_supplement.661.2.Peer-Reviewed Original Research
2000
Fibrillarin-associated Box C/D Small Nucleolar RNAs inTrypanosoma brucei SEQUENCE CONSERVATION AND IMPLICATIONS FOR 2′-O-RIBOSE METHYLATION OF rRNA*
Dunbar D, Wormsley S, Lowe T, Baserga S. Fibrillarin-associated Box C/D Small Nucleolar RNAs inTrypanosoma brucei SEQUENCE CONSERVATION AND IMPLICATIONS FOR 2′-O-RIBOSE METHYLATION OF rRNA*. Journal Of Biological Chemistry 2000, 275: 14767-14776. PMID: 10747997, DOI: 10.1074/jbc.m001180200.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceChromosomal Proteins, Non-HistoneCloning, MolecularConserved SequenceDNA PrimersMethylationMolecular Sequence DataPrecipitin TestsRabbitsRiboseRNA, ProtozoanRNA, RibosomalRNA, Small NuclearSequence Homology, Amino AcidSequence Homology, Nucleic AcidTrypanosoma brucei bruceiConceptsRibose methylationBox C/D snoRNAsMethylation guide snoRNAsSmall nucleolar RNAsAncient eukaryotesBrucei extractsComparative genomicsEarly eukaryotesGuide snoRNAsD snoRNAsFibrillarin proteinSequence conservationSnoRNA sequencesNucleolar RNAsNucleotides upstreamBox CBox DSnoRNAsT. bruceiCommon proteinsEukaryotesFibrillarinRNA 1MethylationRRNA