2014
Making Ribosomes: Pre-rRNA Transcription and Processing
McCann K, Baserga S. Making Ribosomes: Pre-rRNA Transcription and Processing. 2014, 217-232. DOI: 10.1007/978-3-319-05687-6_9.Peer-Reviewed Original Research
2012
The Box C/D sRNP dimeric architecture is conserved across Kingdom Archaea
Baserga S, Phipps K, Taylor D, Wang H. The Box C/D sRNP dimeric architecture is conserved across Kingdom Archaea. The FASEB Journal 2012, 26: 773.2-773.2. DOI: 10.1096/fasebj.26.1_supplement.773.2.Peer-Reviewed Original ResearchBox C/D sRNPDimeric architectureBox C/DRecent structural studiesSRNP assemblyArchaeal speciesArchaeal kingdomOligomeric architectureKingdom ArchaeaPyrococcus abyssiArchaeoglobus fulgidusMutational analysisSRNPSingle-particle reconstructionStructural determinantsArchaeaStructural studiesEukaryotesSRNAsFulgidusSolfataricusParticle reconstructionRNASpeciesMutations
2011
Small Ribonucleoproteins in Ribosome Biogenesis
Bleichert F, Baserga S. Small Ribonucleoproteins in Ribosome Biogenesis. Protein Reviews 2011, 135-156. DOI: 10.1007/978-1-4614-0514-6_7.ChaptersSmall nucleolar RNPsSite of functionNon-enzymatic functionsRibosome biogenesisFunctional ribosomesEukaryotic cellsSmall ribonucleoproteinSmall RNPsGuide RNANucleotide modificationsRNA componentRNA substratesSubstrate RNAEndonucleolytic cleavageMacromolecular assembliesRNA foldingCurrent understandingRNARNPNucleoliEnzymeLarge macromoleculesAssemblyChaperonesBiogenesis
2000
The genes for small nucleolar RNAs in Trypanosoma brucei are organized in clusters and are transcribed as a polycistronic RNA
Dunbar D, Chen A, Wormsley S, Baserga S. The genes for small nucleolar RNAs in Trypanosoma brucei are organized in clusters and are transcribed as a polycistronic RNA. Nucleic Acids Research 2000, 28: 2855-2861. PMID: 10908346, PMCID: PMC102681, DOI: 10.1093/nar/28.15.2855.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBacteriophage P1Base SequenceBlotting, SouthernChromosome MappingCloning, MolecularDNA Restriction EnzymesGenesMolecular Sequence DataMultigene FamilyPolymerase Chain ReactionReverse Transcriptase Polymerase Chain ReactionRNA, ProtozoanRNA, Small NucleolarTandem Repeat SequencesTranscription, GeneticTrypanosoma brucei brucei
1999
Imp3p and Imp4p, Two Specific Components of the U3 Small Nucleolar Ribonucleoprotein That Are Essential for Pre-18S rRNA Processing
Lee S, Baserga S. Imp3p and Imp4p, Two Specific Components of the U3 Small Nucleolar Ribonucleoprotein That Are Essential for Pre-18S rRNA Processing. Molecular And Cellular Biology 1999, 19: 5441-5452. PMID: 10409734, PMCID: PMC84386, DOI: 10.1128/mcb.19.8.5441.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceGenes, ReporterGenetic TechniquesGenetic VectorsMacromolecular SubstancesMolecular Sequence DataPhosphoproteinsRecombinant Fusion ProteinsRibonucleoproteinsRibonucleoproteins, Small NuclearRibosomal ProteinsRNA PrecursorsRNA, FungalRNA, Ribosomal, 18SSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSequence AlignmentSequence Homology, Amino AcidConceptsU3 small nucleolar ribonucleoproteinSmall nucleolar ribonucleoproteinProtein componentsU3 snoRNPNucleolar ribonucleoproteinGenetic depletionTwo-hybrid methodologyNovel protein componentsPre-rRNA processingUnique protein componentRibosomal proteinsSnoRNA levelsRRNA processingU3 snoRNARRNA precursorIMP proteinU3 RNAS4 familiesPrecise functionSevere defectsCleavage eventsMpp10pProteinSnoRNPsRNA
1996
The U18 snRNA is not essential for pre-rRNA processing in Xenopus laevis.
Dunbar D, Ware V, Baserga S. The U18 snRNA is not essential for pre-rRNA processing in Xenopus laevis. RNA 1996, 2: 324-33. PMID: 8634913, PMCID: PMC1369375.Peer-Reviewed Original Research
1992
Distinct molecular signals for nuclear import of the nucleolar snRNA, U3.
Baserga S, Gilmore-Hebert M, Yang X. Distinct molecular signals for nuclear import of the nucleolar snRNA, U3. Genes & Development 1992, 6: 1120-1130. PMID: 1592260, DOI: 10.1101/gad.6.6.1120.Peer-Reviewed Original ResearchConceptsCap trimethylationNuclear importU3 RNADistinct molecular signalsXenopus oocytesRegulation of importU3 geneCytoplasmic phaseNucleolar snRNAOptimal importU3 snRNAMolecular signalsSnRNAU3 snRNPNucleotidesTrimethylationCytoplasmAutoantigenic proteinsRNAArtificial constructsStemImportOocytesBiogenesisSnRNP
1985
Polyadenylation of a human mitochondrial ribosomal RNA transcript detected by molecular cloning
Baserga S, Linnenbach A, Malcolm S, Ghosh P, Malcolm A, Takeshita K, Forget B, Benz E. Polyadenylation of a human mitochondrial ribosomal RNA transcript detected by molecular cloning. Gene 1985, 35: 305-312. PMID: 4043734, DOI: 10.1016/0378-1119(85)90009-5.Peer-Reviewed Original Research