2001
Fibrillarin and Other snoRNP Proteins Are Targets of Autoantibodies in Xenobiotic-Induced Autoimmunity
Yang J, Baserga S, Turley S, Pollard K. Fibrillarin and Other snoRNP Proteins Are Targets of Autoantibodies in Xenobiotic-Induced Autoimmunity. Clinical Immunology 2001, 101: 38-50. PMID: 11580225, DOI: 10.1006/clim.2001.5099.Peer-Reviewed Original ResearchConceptsSJL/J miceSmall nucleolar ribonucleoproteinSnoRNP proteinsCajal bodiesNucleolar ribonucleoproteinMetaphase chromosomesAmphibian cellsJ miceFibrillarinInterphase cellsProtein componentsNucleolar immunofluorescence patternProteinAnti-nucleolar antibodiesCell linesTarget of autoantibodiesAutoantibody responseAntibody responsePredominant targetImmunofluorescence patternMurineCellsRibonucleoproteinChromosomesMiceAn unexpected, conserved element of the U3 snoRNA is required for Mpp10p association.
Wormsley S, Samarsky D, Fournier M, Baserga S. An unexpected, conserved element of the U3 snoRNA is required for Mpp10p association. RNA 2001, 7: 904-19. PMID: 11421365, PMCID: PMC1370138, DOI: 10.1017/s1355838201010238.Peer-Reviewed Original ResearchConceptsU3 snoRNAU3 snoRNPYeast U3 snoRNAU3 small nucleolar ribonucleoproteinSmall nucleolar ribonucleoproteinSmall nucleolar RNAsStretch of nucleotidesHinge regionBase-pairing interactionsRRNA transcriptsNucleolar RNAsNucleolar ribonucleoproteinConserved elementSequence elementsProtein componentsSnoRNAsProcessing reactionsBase pairsMpp10pBase pairingSnoRNPsFunctional centersRRNACritical roleProtein
2000
Fibrillarin-associated Box C/D Small Nucleolar RNAs inTrypanosoma brucei SEQUENCE CONSERVATION AND IMPLICATIONS FOR 2′-O-RIBOSE METHYLATION OF rRNA*
Dunbar D, Wormsley S, Lowe T, Baserga S. Fibrillarin-associated Box C/D Small Nucleolar RNAs inTrypanosoma brucei SEQUENCE CONSERVATION AND IMPLICATIONS FOR 2′-O-RIBOSE METHYLATION OF rRNA*. Journal Of Biological Chemistry 2000, 275: 14767-14776. PMID: 10747997, DOI: 10.1074/jbc.m001180200.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceChromosomal Proteins, Non-HistoneCloning, MolecularConserved SequenceDNA PrimersMethylationMolecular Sequence DataPrecipitin TestsRabbitsRiboseRNA, ProtozoanRNA, RibosomalRNA, Small NuclearSequence Homology, Amino AcidSequence Homology, Nucleic AcidTrypanosoma brucei bruceiConceptsRibose methylationBox C/D snoRNAsMethylation guide snoRNAsSmall nucleolar RNAsAncient eukaryotesBrucei extractsComparative genomicsEarly eukaryotesGuide snoRNAsD snoRNAsFibrillarin proteinSequence conservationSnoRNA sequencesNucleolar RNAsNucleotides upstreamBox CBox DSnoRNAsT. bruceiCommon proteinsEukaryotesFibrillarinRNA 1MethylationRRNA
1998
M Phase Phosphoprotein 10 Is a Human U3 Small Nucleolar Ribonucleoprotein Component
Westendorf J, Konstantinov K, Wormsley S, Shu M, Matsumoto-Taniura N, Pirollet F, Klier F, Gerace L, Baserga S. M Phase Phosphoprotein 10 Is a Human U3 Small Nucleolar Ribonucleoprotein Component. Molecular Biology Of The Cell 1998, 9: 437-449. PMID: 9450966, PMCID: PMC25272, DOI: 10.1091/mbc.9.2.437.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceBase SequenceCell FractionationCell NucleolusChromosomal Proteins, Non-HistoneCloning, MolecularDactinomycinDNA, ComplementaryHeLa CellsHumansIsoelectric PointMitosisMolecular Sequence DataMolecular WeightNuclear ProteinsPhosphoproteinsRibonucleoproteinsRibonucleoproteins, Small NuclearRNA, Small NuclearSequence Analysis, DNASpecies SpecificityConceptsM-phase phosphoproteinsPrenucleolar bodiesBox C/D snoRNAsU3 small nucleolar RNASmall nucleolar RNAsIsolation of cDNAsHuman U3D snoRNAsRRNA processingNucleolar proteinsP80-coilinNovel proteinNucleolar functionU3 snoRNAChromosome surfaceNucleolar RNAsCell fractionationMpp10FibrillarinInterphase cellsCell cycleRibonucleoprotein componentsM phaseProteinSnoRNAs
1997
Functional separation of pre-rRNA processing steps revealed by truncation of the U3 small nucleolar ribonucleoprotein component, Mpp10
Lee S, Baserga S. Functional separation of pre-rRNA processing steps revealed by truncation of the U3 small nucleolar ribonucleoprotein component, Mpp10. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 13536-13541. PMID: 9391061, PMCID: PMC28341, DOI: 10.1073/pnas.94.25.13536.Peer-Reviewed Original Research
1992
Distinct molecular signals for nuclear import of the nucleolar snRNA, U3.
Baserga S, Gilmore-Hebert M, Yang X. Distinct molecular signals for nuclear import of the nucleolar snRNA, U3. Genes & Development 1992, 6: 1120-1130. PMID: 1592260, DOI: 10.1101/gad.6.6.1120.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceCell NucleusChromosomal Proteins, Non-HistoneMicroinjectionsMolecular Sequence DataMutagenesisNucleic Acid ConformationOocytesPrecipitin TestsRNA CapsRNA, Small NuclearXenopus laevisConceptsCap trimethylationNuclear importU3 RNADistinct molecular signalsXenopus oocytesRegulation of importU3 geneCytoplasmic phaseNucleolar snRNAOptimal importU3 snRNAMolecular signalsSnRNAU3 snRNPNucleotidesTrimethylationCytoplasmAutoantigenic proteinsRNAArtificial constructsStemImportOocytesBiogenesisSnRNP