2016
Immunologic Status Evaluated By the Absolute Lymphocyte/Monocyte Ratio Provides a Powerful Prognostic Tool for Newly Diagnosed Multiple Myeloma
Malek E, Dosani T, Pinto R, Covut F, Akabane H, Driscoll J, De Lima M. Immunologic Status Evaluated By the Absolute Lymphocyte/Monocyte Ratio Provides a Powerful Prognostic Tool for Newly Diagnosed Multiple Myeloma. Blood 2016, 128: 1862. DOI: 10.1182/blood.v128.22.1862.1862.Peer-Reviewed Original ResearchALC/AMC ratioLow ALC/AMC ratioProgression-free survivalAbsolute lymphocyte countAbsolute monocyte countTumor-associated macrophagesHigh absolute monocyte countLow absolute lymphocyte countHost immune statusOverall survivalPrognostic factorsMM patientsHost immune systemPrognostic significanceMultivariate analysisImmune statusSurrogate markerSuperior median progression-free survivalImmune systemPredictors of PFSLymphocyte/monocyte ratioMedian progression-free survivalLonger progression-free survivalDifferent progression-free survivalImmunosuppressive tumor-associated macrophages
2015
Erratum: The cellular immune system in myelomagenesis: NK cells and T cells in the development of MM and their uses in immunotherapies
Dosani T, Carlsten M, Maric I, Landgren O. Erratum: The cellular immune system in myelomagenesis: NK cells and T cells in the development of MM and their uses in immunotherapies. Blood Cancer Journal 2015, 5: e321-e321. PMID: 26140429, PMCID: PMC4526775, DOI: 10.1038/bcj.2015.49.Peer-Reviewed Original ResearchThe cellular immune system in myelomagenesis: NK cells and T cells in the development of MM and their uses in immunotherapies
Dosani T, Carlsten M, Maric I, Landgren O. The cellular immune system in myelomagenesis: NK cells and T cells in the development of MM and their uses in immunotherapies. Blood Cancer Journal 2015, 5: e306-e306. PMID: 25885426, PMCID: PMC4450330, DOI: 10.1038/bcj.2015.32.Peer-Reviewed Original ResearchConceptsDevelopment of MMMultiple myelomaT cellsImmune systemNatural killer T cellsRegulatory T cellsKiller T cellsNatural killer cellsConventional T cellsΓδ T cellsCellular immune systemImmune subsetsNK cellsKiller cellsPeripheral bloodUndetermined significanceImmune cellsMonoclonal gammopathyImmune componentsTumor evolutionBone marrowMyelomagenesisImmunotherapyPrecursor conditionsCurrent literature