2017
Exome analysis of the evolutionary path of hepatocellular adenoma-carcinoma transition, vascular invasion and brain dissemination
Vilarinho S, Erson-Omay E, Mitchell-Richards K, Cha C, Nelson-Williams C, Harmancı AS, Yasuno K, Günel M, Taddei TH. Exome analysis of the evolutionary path of hepatocellular adenoma-carcinoma transition, vascular invasion and brain dissemination. Journal Of Hepatology 2017, 67: 186-191. PMID: 28323122, PMCID: PMC5497691, DOI: 10.1016/j.jhep.2017.03.009.Peer-Reviewed Original ResearchConceptsAdenoma-carcinoma transitionHepatocellular adenomaBrain metastasesHepatocellular carcinomaVascular invasionTumor thrombusCatenin beta 1Rare benign liver tumorMultifocal hepatic lesionsAcute abdominal painBenign liver tumorsPeripheral blood leucocytesSomatic mutationsWhole-exome sequencingParaffin-embedded samplesBrain disseminationAbdominal painLeft hepatectomyMajor complicationsLiver diseaseSpontaneous hemorrhageLeft lobeDisease progressionBlood leucocytesLiver tumors
2016
Protective altruistic phlebotomy: hereditary haemochromatosis presenting as hepatocellular carcinoma in a non-cirrhotic 83-year-old man
Ooka K, Onyiuke I, Zhang X, Taddei TH. Protective altruistic phlebotomy: hereditary haemochromatosis presenting as hepatocellular carcinoma in a non-cirrhotic 83-year-old man. BMJ Case Reports 2016, 2016: bcr2016216649. PMID: 27591041, PMCID: PMC5020720, DOI: 10.1136/bcr-2016-216649.Peer-Reviewed Case Reports and Technical NotesConceptsHepatocellular carcinomaHereditary haemochromatosisSolitary liver tumorSigns of recurrenceAbdominal painElevated transaminasesHepatic manifestationLiver diseaseLate presentationSurveillance imagingIron overloadRoutine phlebotomyLiver tumorsMultisystem disorderCarcinomaHaemochromatosisNew complicationsCirrhosisPartial hepatectomyIron metabolismMenHepatomegalyPainComplicationsHaemosiderosis