Cholesterol and nonalcoholic fatty liver disease: Renewed focus on an old villain
Kerr T, Davidson N, Groszmann R, Iwakiri Y, Taddei T. Cholesterol and nonalcoholic fatty liver disease: Renewed focus on an old villain. Hepatology 2012, 56: 1995-1998. PMID: 23115010, PMCID: PMC3627394, DOI: 10.1002/hep.26088.Peer-Reviewed Original ResearchHMG-CoA reductasePhosphorylation of HMG-CoA reductaseExpression of cholesterol metabolism genesHMG-CoA reductase expressionDysregulated cholesterol metabolismFree cholesterolCholesterol metabolism genesHistological severity of NAFLDMetabolic genesAMP kinaseCoA reductaseLDL receptor expressionCholesterol ester hydrolaseDecreased phosphorylationDisease phenotypeLiver-related mortalitySeverity of NAFLDCholesterol metabolismEster hydrolaseCholesterol synthesisNonalcoholic fatty liver diseaseACAT-2Fatty liver diseaseSirtuin 1Receptor expression