Association of BNT162b2 mRNA and mRNA-1273 Vaccines With COVID-19 Infection and Hospitalization Among Patients With Cirrhosis
John BV, Deng Y, Scheinberg A, Mahmud N, Taddei TH, Kaplan D, Labrada M, Baracco G, Dahman B. Association of BNT162b2 mRNA and mRNA-1273 Vaccines With COVID-19 Infection and Hospitalization Among Patients With Cirrhosis. JAMA Internal Medicine 2021, 181: 1306-1314. PMID: 34254978, PMCID: PMC8278308, DOI: 10.1001/jamainternmed.2021.4325.Peer-Reviewed Original ResearchConceptsCOVID-19 infectionCOVID-19-related hospitalizationBNT162b2 mRNAFirst doseCohort studySecond doseMRNA vaccinesClinical trialsControl groupPropensity-matched control groupPhase 3 clinical trialsCOVID-19 mRNA vaccinesAssociation of vaccinationRetrospective cohort studyUS veteran populationAssociation of receiptVeterans Health AdministrationCoronavirus disease 2019COVID-19 hospitalizationMRNA vaccine administrationCOVID-19Vaccine recipientsImmune dysregulationModerna mRNAMedian ageInpatient Gastroenterology Consultation and Outcomes of Cirrhosis-Related Hospitalizations in Two Large National Cohorts
Serper M, Kaplan DE, Lin M, Taddei TH, Parikh ND, Werner RM, Tapper EB. Inpatient Gastroenterology Consultation and Outcomes of Cirrhosis-Related Hospitalizations in Two Large National Cohorts. Digestive Diseases And Sciences 2021, 67: 2094-2104. PMID: 34374917, PMCID: PMC10849043, DOI: 10.1007/s10620-021-07150-8.Peer-Reviewed Original ResearchConceptsLength of stayPropensity-matched analysisNational cohortSpecialty careHigher LOSAlcohol-associated hepatitisCirrhosis-related admissionsOutcome of cirrhosisSpontaneous bacterial peritonitisLarge national cohortCirrhosis complicationsHepatology consultationVA cohortIndex admissionGastroenterology consultationClinical characteristicsBacterial peritonitisLiver diseaseReadmission riskICD9/10 codesRisk regressionInpatient consultationsPatientsLower mortalityDisease severityPatient Frailty Is Independently Associated With the Risk of Hospitalization for Acute‐on‐Chronic Liver Failure
Shah S, Goldberg DS, Kaplan DE, Sundaram V, Taddei TH, Mahmud N. Patient Frailty Is Independently Associated With the Risk of Hospitalization for Acute‐on‐Chronic Liver Failure. Liver Transplantation 2021, 27: 16-26. PMID: 32946660, PMCID: PMC8249075, DOI: 10.1002/lt.25896.Peer-Reviewed Original ResearchMeSH KeywordsAcute-On-Chronic Liver FailureFrailtyHospitalizationHumansLiver CirrhosisLiver TransplantationPrognosisRetrospective StudiesConceptsChronic liver failureFrailty scoreACLF mortalityPatient frailtyLiver failureLongterm survivalPoorer longterm survivalImpact of frailtyRisk of hospitalizationTime of hospitalizationWait-list mortalityACLF developmentCirrhosis hospitalizationsFrail outpatientsTransplant evaluationFirst hospitalizationPosttransplant outcomesTransplant candidatesCox analysisRetrospective studyCox regressionUS veteransRisk factorsHospitalizationAdjusted model