2024
Improving lifestyle behaviors during chemotherapy for breast cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) Trial
Puklin L, Ferrucci L, Harrigan M, McGowan C, Zupa M, Cartmel B, Li F, Ligibel J, Spiegelman D, Sharifi M, Sanft T, Irwin M. Improving lifestyle behaviors during chemotherapy for breast cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) Trial. Cancer 2024, 130: 2440-2452. PMID: 38470431, PMCID: PMC11214600, DOI: 10.1002/cncr.35280.Peer-Reviewed Original ResearchPhysical activityDiet qualityHEI-2015Strength trainingLifestyle behaviorsHealthy Eating Index (HEI)-2015Breast cancerAssociated with baseline fatigueImprove physical activityImprove lifestyle behaviorsHigher HEI-2015Associated with higher oddsExercise interventionUsual careIntervention armIntervention groupBaseline fatigueLifestyle interventionYearlong interventionLower fatigueHigher oddsSecondary analysisLogistic regressionNewly diagnosed patientsStudy arms
2022
Factors associated with sleep health in young women after breast cancer treatment
Hwang Y, Conley S, Jeon S, Redeker N, Sanft T, Knobf M. Factors associated with sleep health in young women after breast cancer treatment. Research In Nursing & Health 2022, 45: 680-692. PMID: 36102624, DOI: 10.1002/nur.22264.Peer-Reviewed Original ResearchConceptsPoor sleep healthSleep healthCognitive appraisalPittsburgh Sleep Quality IndexWorse family functioningBreast cancerPsychological symptom distressYoung womenContext of familyFamily functioningDiverse cancer survivorsRoutine survivorship carePsychosocial variablesCross-sectional designMediation effectSleep Quality IndexSleep health disparitiesBreast cancer treatmentSignificant clinical problemPsychosocial factorsNon-Hispanic whitesHalf of participantsSurvivorship careCancer survivorsMean ageRandomized trial of diet and exercise on chemotherapy completion in women with breast cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) study.
Sanft T, Harrigan M, Cartmel B, Li F, Zupa M, McGowan C, Ferrucci L, Puklin L, Nguyen T, Tanasijevic A, Neuhouser M, Hershman D, Basen-Engquist K, Jones B, Knobf M, Chagpar A, Silber A, Ligibel J, Irwin M. Randomized trial of diet and exercise on chemotherapy completion in women with breast cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) study. Journal Of Clinical Oncology 2022, 40: 12007-12007. DOI: 10.1200/jco.2022.40.16_suppl.12007.Peer-Reviewed Original ResearchRelative dose intensityHigh relative dose intensityBreast cancerDose-response effectPhysical activityPA interventionsNeoadjuvant chemotherapyChemotherapy completionDiet qualityStage I breast cancerEndocrine therapy adherenceTrial of dietDifferent chemotherapy regimensI breast cancerBody mass indexPatient-reported outcomesHealthy Eating IndexBetter diet qualityHigh physical activityMore physical activityElectronic medical recordsChi-square testUC participantsChemotherapy regimensSecondary endpoints0590 Factors Associated with Sleep Health in Young Women After Breast Cancer Treatment
Hwang Y, Conley S, Jeon S, Redeker N, Sanft T, Knobf M. 0590 Factors Associated with Sleep Health in Young Women After Breast Cancer Treatment. Sleep 2022, 45: a259-a260. DOI: 10.1093/sleep/zsac079.587.Peer-Reviewed Original ResearchPittsburgh Sleep Quality IndexPoor sleep healthSleep healthBreast cancerPsychosocial dataGlobal Pittsburgh Sleep Quality IndexYoung womenCancer treatmentRoutine survivorship careSevere night sweatsSleep Quality IndexBreast cancer treatmentCross-sectional studyPrimary cancer treatmentSignificant clinical problemYears of ageQuality of lifeNon-Hispanic whitesWarrants further investigationEndocrine therapyGeneral Functioning subscaleNight sweatsSurvivorship careClinical factorsCancer survivors