2024
Barriers to and facilitators of improving physical activity and nutrition behaviors during chemotherapy for breast cancer: a sequential mixed methods study
Puklin L, Irwin M, Sanft T, Ferrucci L, Harrigan M, McGowan C, Cartmel B, Zupa M, Winer E, Deyling M, Ligibel J, Basen-Engquist K, Spiegelman D, Sharifi M. Barriers to and facilitators of improving physical activity and nutrition behaviors during chemotherapy for breast cancer: a sequential mixed methods study. Supportive Care In Cancer 2024, 32: 590. PMID: 39141176, DOI: 10.1007/s00520-024-08789-5.Peer-Reviewed Original ResearchConceptsPhysical activityLifestyle interventionSelf-reported PA questionnaireSelf-reported diet qualityBreast cancerHealthy Eating Index-2015Stage I-III breast cancerBenefits of PASequential mixed methods studyI-III breast cancerChemotherapy-related symptomsMixed methods studyThematic content analysisBehavioral goalsSense of controlBody mass indexPA questionnaireSemi-structured interviewsMean body mass indexTranscribed verbatimIntervention armTailored educationDiet qualityNutritional behaviorMental benefitsExercise and Nutrition to Improve Cancer Treatment-Related Outcomes (ENICTO)
Schmitz K, Brown J, Irwin M, Robien K, Scott J, Berger N, Caan B, Cercek A, Crane T, Evans S, Ligibel J, Meyerhardt J, Agurs-Collins T, Basen-Engquist K, Bea J, Cai S, Cartmel B, Chinchilli V, Demark-Wahnefried W, Dieli-Conwright C, DiPietro L, Doerksen S, Edelstein S, Elena J, Evans W, Ferrucci L, Foldi J, Freylersythe S, Furberg H, Jones L, Levine R, Moskowitz C, Owusu C, Penedo F, Rabin B, Ratner E, Rosenzweig M, Salz T, Sanft T, Schlumbrecht M, Spielmann G, Thomson C, Tjaden A, Weiser M, Yang S, Yu A, Perna F, Caan B, Anderson S, Bahia H, Castillo A, Feliciano E, Johnson K, Ross M, Weltzein E, Brown J, Albarado B, Compton S, Green T, Nash R, Nauta P, Welch M, Yang S, Meyerhardt J, Dieli-Conwright C, Nguyen D, Pena A, Spielmann G, Kim Y, Evans W, Bea J, Blew R, Crane T, Bhatti A, Clavon R, Erlandsen S, Freylersythe S, Hollander K, Lopez-Pentecost M, Penedo F, Rolle L, Rossi P, Schlumbrecht M, Wheeler M, Irwin M, Cao A, Cartmel B, Ferrucci L, Gottlieb L, Harrigan M, Li F, McGowan C, Puklin L, Ratner E, Sanft T, Zupa M, Berger N, Cerne S, Mills C, Conochan S, Hundal J, Owusu C, Ligibel J, Campbell N, DiGuglielmo K, Kemp W, Maples-Campbell C, Nguyen T, Oppenheim J, Tanasijevic A, Thomson C, Yung A, Basen-Engquist K, Loomba P, Chinchilli V, Schmitz K, Binder J, Doerksen S, Foldi J, Garrett S, Scalise R, Sobolewski M, White L, Scott J, Cercek A, Cai S, Cao S, Furberg H, Harrison J, Jones L, Lee C, Levine R, Michalski M, Moskowitz C, Novo R, Rabazzi J, Stoeckel K, Salz T, Weiser M, Yu A, Demark-Wahnefried W, Robien K, Evans S, DiPietro L, Duong B, Edelstein S, Helmchen L, Le D, McCleary C, Tjaden A, Wopat H, Rabin B, Perna F, Agurs-Collins T, Czajkowski S, Elena J, Nebeling L, Norton W. Exercise and Nutrition to Improve Cancer Treatment-Related Outcomes (ENICTO). Journal Of The National Cancer Institute 2024, djae177. PMID: 39118255, DOI: 10.1093/jnci/djae177.Peer-Reviewed Original ResearchSelf-reported physical functionTreatment-related outcomesTreatment-related side effectsRisk of suboptimal outcomesExercise interventionOncology carePhysical functionNational Cancer InstituteNutrition ProgramIntervention effectsCommon Data ElementsExerciseCancer InstituteCommunity opportunitiesData elementsStandard of careInterventionCareCancer patientsNutritionRelative dose intensityOutcomesSuboptimal outcomesCancer treatmentChemotherapy relative dose intensityAnxiety and fear of cancer recurrence as predictors of subsequent pain interference in early cancer survivorship: Exploring the moderating roles of cognitive and emotional factors
Gnall K, Emrich M, Magin Z, Park C, Bellizzi K, Sanft T. Anxiety and fear of cancer recurrence as predictors of subsequent pain interference in early cancer survivorship: Exploring the moderating roles of cognitive and emotional factors. Journal Of Behavioral Medicine 2024, 47: 980-993. PMID: 39110352, DOI: 10.1007/s10865-024-00506-1.Peer-Reviewed Original ResearchFear of cancer recurrencePain interferenceCancer survivorsAssociated with greater pain interferenceGreater pain interferencePrimary cancer treatmentCancer recurrenceQuality of lifeCancer survivorshipLonger-term painSelf-report measuresEmotion regulation difficultiesCancer treatmentConsequence beliefsChronic beliefsCognitive/emotional factorsPsychological treatmentLongitudinal studyPotential moderatorsAnxietyRegulation difficultiesPainFollow-upEmotional factorsSurvivorsLongitudinal Curriculum to Address Wellness and Professional Development in a Hematology/Oncology Fellowship Program
Srikumar T, Stempel J, Goldberg S, Podoltsev N, Braun D, Lee A, Sanft T. Longitudinal Curriculum to Address Wellness and Professional Development in a Hematology/Oncology Fellowship Program. EMJ Oncology 2024, 1: 37-39. DOI: 10.33590/oncolamj/zgwb5064.Peer-Reviewed Original ResearchLongitudinal curriculum to address wellness and professional development in a hematology/oncology fellowship program.
Srikumar T, Stempel J, Goldberg S, Podoltsev N, Braun D, Lee A, Sanft T. Longitudinal curriculum to address wellness and professional development in a hematology/oncology fellowship program. Journal Of Clinical Oncology 2024, 42: 9004-9004. DOI: 10.1200/jco.2024.42.16_suppl.9004.Peer-Reviewed Original ResearchNeeds assessmentLongitudinal curriculumPatient Health Questionnaire 2Score of self-efficacyGeneral Self-Efficacy ScaleFellowship programsBaseline needs assessmentFaculty-led sessionsProfessional boundary settingSelf-Efficacy ScaleLevels of depressionProfessional developmentFirst-year fellowsDidactic sessionsPrevent burnoutChi-square testAcademic yearDebriefing sessionsQuestionnaire 2Baseline assessmentSelf-efficacyProfessional development skillsDepressed moodLeadership skillsBurnoutA medical school curriculum to foster the physician-patient relationship through narrative medicine.
Yao J, Hunter C, Jaber Chehayeb R, Sanft T, Prsic E, Dunne D, Kang-Giaimo A. A medical school curriculum to foster the physician-patient relationship through narrative medicine. Journal Of Clinical Oncology 2024, 42: e21015-e21015. DOI: 10.1200/jco.2024.42.16_suppl.e21015.Peer-Reviewed Original ResearchDoctor-patient relationshipPatient storiesNarrative medicineTraining sessionsStrong doctor-patient relationshipOptimal quality careThird-year medical studentsPhysician-patient relationshipMedical school curriculumYear medical studentsImprove well-beingMedical education toolThematic analysis of responsesNarrative medicine curriculumDoctor patient relationshipPre-clerkship studentsMedicine skillsYale School of MedicineQuality careMedical students' senseMedicine curriculumPatient relationshipThematic analysisInterviewed patientsSchool of MedicineImproving lifestyle behaviors during chemotherapy for breast cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) Trial
Puklin L, Ferrucci L, Harrigan M, McGowan C, Zupa M, Cartmel B, Li F, Ligibel J, Spiegelman D, Sharifi M, Sanft T, Irwin M. Improving lifestyle behaviors during chemotherapy for breast cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) Trial. Cancer 2024, 130: 2440-2452. PMID: 38470431, PMCID: PMC11214600, DOI: 10.1002/cncr.35280.Peer-Reviewed Original ResearchPhysical activityDiet qualityHEI-2015Strength trainingLifestyle behaviorsHealthy Eating Index (HEI)-2015Breast cancerAssociated with baseline fatigueImprove physical activityImprove lifestyle behaviorsHigher HEI-2015Associated with higher oddsExercise interventionUsual careIntervention armIntervention groupBaseline fatigueLifestyle interventionYearlong interventionLower fatigueHigher oddsSecondary analysisLogistic regressionNewly diagnosed patientsStudy armsImpact of the Breast Cancer Index for Extended Endocrine Decision-Making: First Results of the Prospective BCI Registry Study.
Sanft T, Wong J, O'Neal B, Siuliukina N, Jankowitz R, Pegram M, Fox J, Zhang Y, Treuner K, O'Shaughnessy J. Impact of the Breast Cancer Index for Extended Endocrine Decision-Making: First Results of the Prospective BCI Registry Study. Journal Of The National Comprehensive Cancer Network 2024, 22: 99-107. PMID: 38437792, DOI: 10.6004/jnccn.2023.7087.Peer-Reviewed Original ResearchBenefit of endocrine therapyBreast Cancer IndexPatient satisfactionEndocrine therapyRegistry studyReduce patient concernsPhysician decision-makingClinical practiceEarly-stage breast cancerIncrease physician confidenceCancer indexHormone receptor-positive early-stage breast cancerDrug safetyPhysician recommendationMedication adherencePhysician confidenceWilcoxon signed rank testPatient concernsClinical careDecision-makingPatient preferencesLate distant recurrencePhysiciansTest questionnaireLong-term outcomesPhysical health and function trajectories in adults with cancer: psychosocial predictors of class membership
Bellizzi K, Park C, Lee J, Harel O, Sanft T, Fritzson E, Salafia C, Ligus K, Gnall K, Magin Z. Physical health and function trajectories in adults with cancer: psychosocial predictors of class membership. Journal Of Cancer Survivorship 2024, 1-11. PMID: 38289507, PMCID: PMC11286833, DOI: 10.1007/s11764-024-01540-3.Peer-Reviewed Original ResearchPhysical healthTrajectory class membershipPsychosocial predictorsGeneral healthDiagnosed adult cancer patientsHealth survey measuresFunction trajectoriesAdult cancer patientsPredictors of trajectory class membershipMultinomial logistic regression modelLogistic regression modelsTrajectory of recoveryPhysical functionBodily painSF-12Estimate associationsBaseline assessmentDeclining scoresYale Cancer CenterClass membershipGrowth mixture modelingPattern of predictorsLogistic regressionDaily activitiesHealth
2023
SIOG2023-5-P-388 Social support buffers the effect of social deprivation on comorbidity burden in adults with cancer
Bellizzi K, Ligus K, Salafia C, Sanft T, Park C. SIOG2023-5-P-388 Social support buffers the effect of social deprivation on comorbidity burden in adults with cancer. Journal Of Geriatric Oncology 2023, 14: s81-s82. DOI: 10.1016/s1879-4068(23)00426-5.Peer-Reviewed Original Research
2022
NCCN Guidelines® Insights: Survivorship, Version 1.2022.
Sanft T, Day A, Peterson L, Rodriguez MA, Ansbaugh S, Armenian S, Baker KS, Ballinger T, Broderick G, Demark-Wahnefried W, Dickinson K, Fairman NP, Friedman DL, Goldman M, Henry NL, Hill-Kayser C, Hudson M, Khakpour N, Koura D, McDonough AL, Melisko M, Mooney K, Moore HCF, Moryl N, Neuman H, O'Connor T, Overholser L, Paskett ED, Patel C, Pirl W, Porpiglia A, Ruddy KJ, Schapira L, Shockney L, Smith S, Syrjala KL, Tevaarwerk A, Yang EH, Zee P, McMillian NR, Freedman-Cass DA. NCCN Guidelines® Insights: Survivorship, Version 1.2022. Journal Of The National Comprehensive Cancer Network 2022, 20: 1080-1090. PMID: 36240847, DOI: 10.6004/jnccn.2022.0052.Peer-Reviewed Original ResearchFactors associated with sleep health in young women after breast cancer treatment
Hwang Y, Conley S, Jeon S, Redeker N, Sanft T, Knobf M. Factors associated with sleep health in young women after breast cancer treatment. Research In Nursing & Health 2022, 45: 680-692. PMID: 36102624, DOI: 10.1002/nur.22264.Peer-Reviewed Original ResearchConceptsPoor sleep healthSleep healthCognitive appraisalPittsburgh Sleep Quality IndexWorse family functioningBreast cancerPsychological symptom distressYoung womenContext of familyFamily functioningDiverse cancer survivorsRoutine survivorship carePsychosocial variablesCross-sectional designMediation effectSleep Quality IndexSleep health disparitiesBreast cancer treatmentSignificant clinical problemPsychosocial factorsNon-Hispanic whitesHalf of participantsSurvivorship careCancer survivorsMean ageEngaging TEAM Medicine in Patient Care: Redefining Cancer Survivorship From Diagnosis.
Alfano CM, Oeffinger K, Sanft T, Tortorella B. Engaging TEAM Medicine in Patient Care: Redefining Cancer Survivorship From Diagnosis. American Society Of Clinical Oncology Educational Book 2022, 42: 1-11. PMID: 35649204, DOI: 10.1200/edbk_349391.Peer-Reviewed Original ResearchConceptsStandard of carePrimary careTeam medicineHealth equityCancer survivorship careLarge multidisciplinary teamNumber of survivorsSurvivorship careHealth care administrationLate effectsCancer survivorshipComplex careHealthy behaviorsMultidisciplinary teamPatient careSurvivors' needsOncologyCareKnowledge deficitsCare administrationPatientsSubspecialistsDiagnosisWorkforce shortagesMedicineWeight gain after breast cancer diagnosis: It's complicated…
Cathcart‐Rake E, Sanft T, Tevaarwerk AJ. Weight gain after breast cancer diagnosis: It's complicated…. Cancer 2022, 128: 3152-3154. PMID: 35781699, DOI: 10.1002/cncr.34343.Peer-Reviewed Original ResearchThe Breast Cancer Index Registry Study: Initial analysis of the first 1,000 patients.
O'Shaughnessy J, Encarnacion C, O'Neal B, Wong J, Siuliukina N, Sanft T, Jankowitz R, Pegram M, Treuner K, Fox J. The Breast Cancer Index Registry Study: Initial analysis of the first 1,000 patients. Journal Of Clinical Oncology 2022, 40: e12513-e12513. DOI: 10.1200/jco.2022.40.16_suppl.e12513.Peer-Reviewed Original ResearchBreast Cancer IndexExtended endocrine therapyLate distant recurrenceBreast cancer patientsRegistry studyEndocrine therapyDistant recurrenceClinicopathological factorsMedication adherenceCancer patientsHigh riskLower riskHormone receptor-positive breast cancer patientsReceptor-positive breast cancer patientsEarly-stage breast cancer patientsNCCN Clinical Practice GuidelinesLong-term clinical outcomesPositive breast cancer patientsAssociated clinicopathological factorsAdjuvant endocrine therapyNode-negative patientsNode-positive patientsPrognostic risk groupsClinical practice guidelinesRoutine clinical careRandomized trial of diet and exercise on chemotherapy completion in women with breast cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) study.
Sanft T, Harrigan M, Cartmel B, Li F, Zupa M, McGowan C, Ferrucci L, Puklin L, Nguyen T, Tanasijevic A, Neuhouser M, Hershman D, Basen-Engquist K, Jones B, Knobf M, Chagpar A, Silber A, Ligibel J, Irwin M. Randomized trial of diet and exercise on chemotherapy completion in women with breast cancer: The Lifestyle, Exercise, and Nutrition Early After Diagnosis (LEANer) study. Journal Of Clinical Oncology 2022, 40: 12007-12007. DOI: 10.1200/jco.2022.40.16_suppl.12007.Peer-Reviewed Original ResearchRelative dose intensityHigh relative dose intensityBreast cancerDose-response effectPhysical activityPA interventionsNeoadjuvant chemotherapyChemotherapy completionDiet qualityStage I breast cancerEndocrine therapy adherenceTrial of dietDifferent chemotherapy regimensI breast cancerBody mass indexPatient-reported outcomesHealthy Eating IndexBetter diet qualityHigh physical activityMore physical activityElectronic medical recordsChi-square testUC participantsChemotherapy regimensSecondary endpointsAncillary treatment referrals and visits after breast cancer surgery in a sociodemographically diverse population.
Chan V, Heller D, Berger E, Capozza S, Greenup R, Sanft T. Ancillary treatment referrals and visits after breast cancer surgery in a sociodemographically diverse population. Journal Of Clinical Oncology 2022, 40: 1533-1533. DOI: 10.1200/jco.2022.40.16_suppl.1533.Peer-Reviewed Original ResearchBreast cancer surgeryProvider referralCancer surgeryMultivariable analysisHigher median household incomeHispanic ethnicityYale New Haven Health SystemMedian household incomeMultivariable logistic regression analysisHealth systemHigh school degreeLarge urban health systemPost-operative morbidityBreast cancer patientsUrban health systemZip codesLogistic regression analysisUrban cancer centerPoor healthcare accessElectronic health recordsAncillary therapySchool degreeCancer CenterCancer patientsTreatment referralEstablishing Goals of Care
Choi A, Sanft T. Establishing Goals of Care. Medical Clinics Of North America 2022, 106: 653-662. PMID: 35725231, DOI: 10.1016/j.mcna.2022.01.007.Peer-Reviewed Original Research0590 Factors Associated with Sleep Health in Young Women After Breast Cancer Treatment
Hwang Y, Conley S, Jeon S, Redeker N, Sanft T, Knobf M. 0590 Factors Associated with Sleep Health in Young Women After Breast Cancer Treatment. Sleep 2022, 45: a259-a260. DOI: 10.1093/sleep/zsac079.587.Peer-Reviewed Original ResearchPittsburgh Sleep Quality IndexPoor sleep healthSleep healthBreast cancerPsychosocial dataGlobal Pittsburgh Sleep Quality IndexYoung womenCancer treatmentRoutine survivorship careSevere night sweatsSleep Quality IndexBreast cancer treatmentCross-sectional studyPrimary cancer treatmentSignificant clinical problemYears of ageQuality of lifeNon-Hispanic whitesWarrants further investigationEndocrine therapyGeneral Functioning subscaleNight sweatsSurvivorship careClinical factorsCancer survivorsOn Crying
Sanft T. On Crying. The Oncologist 2022, 27: 424-425. PMID: 35522560, PMCID: PMC9074966, DOI: 10.1093/oncolo/oyac043.Peer-Reviewed Original Research