Ibrutinib in chronic lymphocytic leukemia
Reddy N, Sethi T. Ibrutinib in chronic lymphocytic leukemia. International Journal Of Hematologic Oncology 2015, 4: 143-150. DOI: 10.2217/ijh.15.15.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsB cell receptorTyrosine kinaseKey survival pathwaysMalignant B cellsSignal transductionKinase pathwayBruton's tyrosine kinaseSurvival pathwaysCell survivalSignal triggersB cellsPathwayChronic lymphocytic leukemiaB cell proliferationKey roleTumor microenvironmentTumor malignancyCellsTransductionKinaseLymphocytic leukemia