2020
Constant-severe pain in chronic pancreatitis is associated with genetic loci for major depression in the NAPS2 cohort
Dunbar E, Greer PJ, Melhem N, Alkaade S, Amann ST, Brand R, Coté GA, Forsmark CE, Gardner TB, Gelrud A, Guda NM, LaRusch J, Lewis MD, Machicado JD, Muniraj T, Papachristou GI, Romagnuolo J, Sandhu BS, Sherman S, Wilcox CM, Singh VK, Yadav D, Whitcomb DC. Constant-severe pain in chronic pancreatitis is associated with genetic loci for major depression in the NAPS2 cohort. Journal Of Gastroenterology 2020, 55: 1000-1009. PMID: 32681239, PMCID: PMC9124361, DOI: 10.1007/s00535-020-01703-w.Peer-Reviewed Original ResearchConceptsConstant severe painRecurrent acute pancreatitisChronic pancreatitisDepression-associated genesCP patientsPain severityAntidepressant usePancreatitis patientsPain experienceProspective randomized trialsAntidepressant medication usePattern of painCase report formsChronic opioidsIslet autotransplantationAntidepressant therapyTotal pancreatectomyMedication usePain managementRandomized trialsCounseling patientsRetrospective studyAcute pancreatitisClinical trialsMajor depression
2013
Total pancreatectomy and islet autotransplantation in chronic pancreatitis: Recommendations from PancreasFest
Bellin MD, Freeman ML, Gelrud A, Slivka A, Clavel A, Humar A, Schwarzenberg SJ, Lowe ME, Rickels MR, Whitcomb DC, Matthews JB, Amann S, Andersen D, Anderson M, Baillie J, Block G, Brand R, Chari S, Cook M, Cote G, Dunn T, Frulloni L, Greer J, Hollingsworth M, Kim K, Larson A, Lerch M, Lin T, Muniraj T, Robertson R, Sclair S, Singh S, Stopczynski R, Toledo F, Wilcox C, Windsor J, Yadav D. Total pancreatectomy and islet autotransplantation in chronic pancreatitis: Recommendations from PancreasFest. Pancreatology 2013, 14: 27-35. PMID: 24555976, PMCID: PMC4058640, DOI: 10.1016/j.pan.2013.10.009.Peer-Reviewed Original ResearchConceptsChronic pancreatitisIslet autotransplantationTotal pancreatectomyPancreatic cancerQualified multidisciplinary teamHigh-risk patientsSevere diabetes mellitusLong-term managementRisk patientsSevere complicationsDiabetes mellitusSurgical optionsCandidate patientsClinical evaluationMulti-disciplinary teamSurgical proceduresConsensus meetingHigh riskTPIATMultidisciplinary teamNutrition evaluationOptimal timingPancreatitisCareful evaluationPancreatectomy