2021
Pancreatic Neuroendocrine Tumors
Muniraj T, Aslanian H. Pancreatic Neuroendocrine Tumors. 2021, 1933-1951. DOI: 10.1007/978-3-030-30192-7_81.Peer-Reviewed Original ResearchNeuroendocrine tumorsProlongs disease-free survivalDiagnosis of NETsNon-functioning neuroendocrine tumoursDisease-free survivalCareful clinical historyTreatment of choicePancreatic neuroendocrine tumorsQuality of lifeHormone hypersecretionMetastatic diseaseNonfunctional tumorsSurgical resectionTreatment modalitiesClinical historyPotential treatmentHeterogeneous groupTumorsMass effectAgeTreatmentLaboratory testsHypersecretionResectionPatientsResection of pancreatic cystic neoplasms in recurrent acute pancreatitis prevents recurrent pancreatitis but does not identify more malignancies
Muniraj T, Aslanian HR, Laine L, Jamidar PA, Farrell JF, Mitchell KA, Salem RR. Resection of pancreatic cystic neoplasms in recurrent acute pancreatitis prevents recurrent pancreatitis but does not identify more malignancies. World Journal Of Gastroenterology 2021, 27: 1630-1642. PMID: 33958848, PMCID: PMC8058652, DOI: 10.3748/wjg.v27.i15.1630.Peer-Reviewed Original ResearchConceptsIntra-ductal papillary mucinous neoplasmRecurrent acute pancreatitisPancreatic cystic neoplasmsCystic neoplasmsBD-IPMNAcute pancreatitisCause of pancreatitisRole of resectionMucinous cystic neoplasmPrevalence of malignancyPapillary mucinous neoplasmSerous cystic neoplasmsCross-sectional imagingMean episodesRAP patientsSurgical resectionCyst resectionMD-IPMNPrimary outcomeIPMN patientsRecurrent pancreatitisRetrospective studyCyst featuresGallstone aetiologyMucinous neoplasms
2020
Endoscopic ultrasound‐guided fine needle aspiration cytology diagnosis of upper gastrointestinal tract mesenchymal tumors: Impact of rapid onsite evaluation and correlation with histopathologic follow‐up
Gilani SM, Muniraj T, Aslanian HR, Cai G. Endoscopic ultrasound‐guided fine needle aspiration cytology diagnosis of upper gastrointestinal tract mesenchymal tumors: Impact of rapid onsite evaluation and correlation with histopathologic follow‐up. Diagnostic Cytopathology 2020, 49: 203-210. PMID: 33006819, DOI: 10.1002/dc.24631.Peer-Reviewed Original ResearchConceptsRapid onsite evaluationSubsequent surgical resectionUpper gastrointestinal tractMesenchymal tumorsSurgical resectionCell blocksEUS-FNAFine needle aspiration cytology diagnosisUltrasound-guided fine-needle aspiration cytologyEndoscopic ultrasound-guided fine-needle aspiration cytologyFine needle aspiration cytologyOnsite evaluationAdditional ancillary testingNeedle aspiration cytologyDiagnostic challengeCytologic casesDiagnostic yieldAncillary testingAspiration cytologyCytologic diagnosisGastrointestinal tractMorphologic overlapCytology diagnosisElectronic databasesLesional materialLow serum trypsinogen levels in chronic pancreatitis: Correlation with parenchymal loss, exocrine pancreatic insufficiency, and diabetes but not CT-based cambridge severity scores for fibrosis
Zhan W, Akshintala V, Greer PJ, Greer JB, Alkaade S, Anderson MA, Muniraj T, Papachristou GI, Sandhu BS, Slivka A, Wilcox CM, Bellin MD, Singh VK, Yadav D, Brand RE, Whitcomb DC, Group F. Low serum trypsinogen levels in chronic pancreatitis: Correlation with parenchymal loss, exocrine pancreatic insufficiency, and diabetes but not CT-based cambridge severity scores for fibrosis. Pancreatology 2020, 20: 1368-1378. PMID: 32967795, DOI: 10.1016/j.pan.2020.08.025.Peer-Reviewed Original ResearchConceptsSerum trypsinogen levelsChronic pancreatitisTrypsinogen levelsAcinar cell functionCP patientsParenchymal lossCell functionComplex inflammatory disorderExocrine pancreatic insufficiencyCT-based criteriaNAPS2 studySerum trypsinogenAcinar cell lossSurgical resectionFinal cohortInflammatory cellsInflammatory disordersControl subjectsSeverity scoreClinical managementPancreatic insufficiencyStellate cellsNormal rangeCell lossIslet cellsPancreatic Neuroendocrine Tumors
Muniraj T, Aslanian H. Pancreatic Neuroendocrine Tumors. 2020, 1-19. DOI: 10.1007/978-3-319-90761-1_81-1.Peer-Reviewed Original ResearchNeuroendocrine tumorsProlongs disease-free survivalDiagnosis of NETsNon-functioning neuroendocrine tumoursDisease-free survivalCareful clinical historyTreatment of choicePancreatic neuroendocrine tumorsQuality of lifeHormone hypersecretionMetastatic diseaseNonfunctional tumorsSurgical resectionTreatment modalitiesClinical historyPotential treatmentHeterogeneous groupTumorsMass effectAgeTreatmentLaboratory testsHypersecretionResectionPatients