2021
Pain Experience in Pancreatitis: Strong Association of Genetic Risk Loci for Anxiety and PTSD in Patients With Severe, Constant, and Constant-Severe Pain
Dunbar EK, Greer PJ, Amann ST, Alkaade S, Banks P, Brand R, Conwell DL, Forsmark CE, Gardner TB, Guda NM, Lewis MD, Machicado JD, Muniraj T, Papachristou GI, Romagnuolo J, Sandhu BS, Sherman S, Slivka A, Wilcox CM, Yadav D, Whitcomb DC, Consortium F. Pain Experience in Pancreatitis: Strong Association of Genetic Risk Loci for Anxiety and PTSD in Patients With Severe, Constant, and Constant-Severe Pain. The American Journal Of Gastroenterology 2021, 116: 2128-2136. PMID: 34236339, PMCID: PMC8531869, DOI: 10.14309/ajg.0000000000001366.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderChronic pancreatitisSevere painPain experienceThird of patientsPain management strategiesIdentification of patientsAbsence of painInflammatory syndromePain patternsCP patientsPain categoriesPain locusStudy cohortAcute pancreatitisAdrenal axisCP subjectsPainGenetic predispositionPatientsPsychiatric conditionsGenetic risk lociPTSD riskPancreatitisStress disorder
2016
Racial Differences in the Clinical Profile, Causes, and Outcome of Chronic Pancreatitis
Wilcox CM, Sandhu BS, Singh V, Gelrud A, Abberbock JN, Sherman S, Cote GA, Al-Kaade S, Anderson MA, Gardner TB, Lewis MD, Forsmark CE, Guda NM, Romagnuolo J, Baillie J, Amann ST, Muniraj T, Tang G, Conwell DL, Banks PA, Brand RE, Slivka A, Whitcomb D, Yadav D. Racial Differences in the Clinical Profile, Causes, and Outcome of Chronic Pancreatitis. The American Journal Of Gastroenterology 2016, 111: 1488. PMID: 27527745, PMCID: PMC6196097, DOI: 10.1038/ajg.2016.316.Peer-Reviewed Original ResearchMeSH KeywordsAbdominal PainAdultAgedAtrophyBlack or African AmericanCalcinosisCommon Bile Duct DiseasesConstriction, PathologicExocrine Pancreatic InsufficiencyFemaleHumansMaleMiddle AgedPain MeasurementPancreasPancreatic DiseasesPancreatic DuctsPancreatitis, AlcoholicPancreatitis, ChronicPrevalenceProspective StudiesRisk FactorsSex FactorsSmokingTime FactorsWhite PeopleYoung AdultConceptsChronic pancreatitisBlack patientsClinical profileDuration of CPNorth American Pancreatitis StudiesDuration of diseaseAlcoholic chronic pancreatitisProgression of pancreatitisRacial differencesPrior cholecystectomyPain characteristicsAlcohol etiologyCurrent smokersDisease durationSevere painEndoscopic treatmentWhite patientsRisk factorsPancreatic morphologyUS CentersEpidemiologic studiesPatientsAdvanced changesRetrospective dataDetailed questionnaire