The Crystal Structure Analysis of d(CGCGAASSCGCG)2, a Synthetic DNA Dodecamer Duplex Containing Four 4′-Thio-2′-Deoxythymidine Nucleotides
Boggon T, Hancox E, McAuley-Hecht K, Connolly B, Hunter W, Brown T, Walker R, Leonard G. The Crystal Structure Analysis of d(CGCGAASSCGCG)2, a Synthetic DNA Dodecamer Duplex Containing Four 4′-Thio-2′-Deoxythymidine Nucleotides. Nucleic Acids Research 1996, 24: 951-961. PMID: 8600465, PMCID: PMC145717, DOI: 10.1093/nar/24.5.951.Peer-Reviewed Original ResearchConceptsDodecamer duplexCrystal structure analysisC1'-exo conformationC3'-exo conformationFine structural parametersCrystal structure refinementSugar-phosphate backboneSynthetic dodecamerWater moleculesDNA dodecamer duplexAnalogous sugarsStructure analysisStructure refinementNative dodecamerConformationDodecamerStructural parametersDuplexDeoxythymidine nucleotidesStructureThiosugarsBackboneMoleculesNucleosidesSynthetic