2020
Detection of crown-like structures in breast adipose tissue and clinical outcomes among African-American and White women with breast cancer
Maliniak M, Cheriyan A, Sherman M, Liu Y, Gogineni K, Liu J, He J, Krishnamurti U, Miller-Kleinhenz J, Ashiqueali R, He J, Yacoub R, McCullough L. Detection of crown-like structures in breast adipose tissue and clinical outcomes among African-American and White women with breast cancer. Breast Cancer Research 2020, 22: 65. PMID: 32552729, PMCID: PMC7298873, DOI: 10.1186/s13058-020-01308-4.Peer-Reviewed Original ResearchConceptsBreast adipose tissueHazard ratioBreast cancerAdipose tissueMultivariable Cox proportional hazards modelsWhite womenCox proportional hazards modelProgression-free survivalMedical record reviewCurrent smoking statusConfidence intervalsProportional hazards modelBenign breast tissueBreast cancer prognosisNon-tumor tissuesCrown-like structuresMulti-racial populationEvidence of associationWorse OSWhite patientsClinical outcomesRecord reviewSmoking statusLifestyle factorsMultivariable model
2019
A whole slide image-based machine learning approach to predict ductal carcinoma in situ (DCIS) recurrence risk
Klimov S, Miligy I, Gertych A, Jiang Y, Toss M, Rida P, Ellis I, Green A, Krishnamurti U, Rakha E, Aneja R. A whole slide image-based machine learning approach to predict ductal carcinoma in situ (DCIS) recurrence risk. Breast Cancer Research 2019, 21: 83. PMID: 31358020, PMCID: PMC6664779, DOI: 10.1186/s13058-019-1165-5.Peer-Reviewed Original ResearchConceptsDCIS patientsRecurrence riskDuctal carcinomaScreen-detected breast cancerLong-term outcome dataBreast-conserving surgeryUnmet clinical needNottingham University HospitalsPositive predictive valueAdjuvant radiationIpsilateral recurrenceAdditional therapyMethodsThe cohortHazard ratioLocal recurrenceClinicopathological markersClinicopathological variablesPrimary tumorUniversity HospitalLymphocyte regionBreast cancerOutcome dataBenign ductsPredictive valuePatients