2023
Organ function is preserved despite reorganization of niche architecture in the hair follicle
Wei H, Du S, Parksong J, Pasolli H, Matte-Martone C, Regot S, Gonzalez L, Xin T, Greco V. Organ function is preserved despite reorganization of niche architecture in the hair follicle. Cell Stem Cell 2023, 30: 962-972.e6. PMID: 37419106, PMCID: PMC10362479, DOI: 10.1016/j.stem.2023.06.003.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell DifferentiationEpitheliumHairHair FollicleMiceTransforming Growth Factor betaConceptsNiche architectureDermal papilla fibroblastsDifferentiated lineagesHair follicle growthStereotypic architectureMultipotent progenitorsEpithelial progenitorsFunctional importanceNicheStem cellsFibroblast nicheProgenitorsPowerful modelIntravital imagingDermal papillaFibroblastsHair folliclesFollicle growthOrgan functionLineagesDifferentiationCrosstalkHairProliferationCells
2019
Flexibility sustains epithelial tissue homeostasis
Tai K, Cockburn K, Greco V. Flexibility sustains epithelial tissue homeostasis. Current Opinion In Cell Biology 2019, 60: 84-91. PMID: 31153058, PMCID: PMC6756930, DOI: 10.1016/j.ceb.2019.04.009.Peer-Reviewed Original ResearchConceptsEpithelial homeostasisEpithelial tissue homeostasisLive-imaging techniquesEpithelial cell interactionsIndividual epithelial cellsOrganism's lifetimeTissue homeostasisCell plasticityCell biologyMolecular mechanismsPathological settingsCell interactionsHomeostasisEpithelial cellsRecent advancesGeneticsBiologyMutationsImportant implicationsEpitheliumMechanismPlasticityCells
2001
Argosomes A Potential Vehicle for the Spread of Morphogens through Epithelia
Greco V, Hannus M, Eaton S. Argosomes A Potential Vehicle for the Spread of Morphogens through Epithelia. Cell 2001, 106: 633-645. PMID: 11551510, DOI: 10.1016/s0092-8674(01)00484-6.Peer-Reviewed Original ResearchConceptsWingless proteinFormation of morphogen gradientsImaginal disc epitheliumCell biological mechanismsSpreading of morphogensDisc epitheliumMorphogen gradientsArgosomesTissue patterningMorphogenWinglessMembrane fragmentsCell membraneProteinBiological mechanismsCellsAdjacent tissuesMembraneEndosomesBasolateral membranePotential vehicleTissueFragments