2022
Patient-reported outcomes among males undergoing prostate cancer germline testing: Interim results from the Prostate Cancer Genetic Risk, Experience, and Support Study (PROGRESS) Registry.
Giri V, Hartman R, Gross L, Keith S. Patient-reported outcomes among males undergoing prostate cancer germline testing: Interim results from the Prostate Cancer Genetic Risk, Experience, and Support Study (PROGRESS) Registry. Journal Of Clinical Oncology 2022, 40: 10595-10595. DOI: 10.1200/jco.2022.40.16_suppl.10595.Peer-Reviewed Original ResearchPatient-reported outcomesGermline testingGenetic testingPROGRESS registryDecisional conflictNon-Hispanic/LatinoDiagnosis of PCaCancer genetic riskGenetic counselingCancer geneticsPatient experience informationStudy registryGleason scoreRegistry participantsFamily historyRegistryGenetic resultsAfrican American malesCategorical variablesGenetic riskSAS 9.4Traditional genetic counselingDemographic informationGenetic mutationsMen
2021
Helix: A Digital Tool to Address Provider Needs for Prostate Cancer Genetic Testing in Clinical Practice
Giri V, Walker A, Gross L, Trabulsi E, Lallas C, Kelly W, Gomella L, Fischer C, Loeb S. Helix: A Digital Tool to Address Provider Needs for Prostate Cancer Genetic Testing in Clinical Practice. Clinical Genitourinary Cancer 2021, 20: e104-e113. PMID: 35012874, DOI: 10.1016/j.clgc.2021.11.009.Peer-Reviewed Original ResearchConceptsGermline testingFamily historyClinical practiceChronic Diseases frameworkMultiple family historyMaternal family historyCancer genetic testingMedical oncologistsAdvanced PCaPCa riskProvider interviewsAggressive PCaRadiation oncologistsPractice settingsGenetic testingLarger studyDisease frameworkClinical useOncologistsLower ratesPractice gapMenDescriptive statisticsPhiladelphia areaProvidersTesting a Prostate Cancer Educational Intervention in High-Burden Neighborhoods
Zeigler-Johnson C, Madsen R, Keith S, Glanz K, Quinn A, Giri V, Bowen E, Sauls D, Leader A. Testing a Prostate Cancer Educational Intervention in High-Burden Neighborhoods. Journal Of Racial And Ethnic Health Disparities 2021, 9: 2477-2484. PMID: 34748171, PMCID: PMC9973384, DOI: 10.1007/s40615-021-01183-5.Peer-Reviewed Original ResearchConceptsIntervention groupHealthy lifestyle (HL) control groupProstate cancer educational interventionProstate cancer risk factorsEducational interventionCancer risk factorsMixed effects regression modelsOutcome assessment measuresRisk factorsPCa knowledgeRisk menControl groupControl interventionsEthnic disparitiesLevel of knowledgePCa outcomesIntervention effectsHealth concernStudy sampleEffects regression modelsInterventionMenOutcomesBaselineDescriptive statisticsPretest Genetic Education Video Versus Genetic Counseling for Men Considering Prostate Cancer Germline Testing: A Patient-Choice Study to Address Urgent Practice Needs
Russo J, McDougall C, Bowler N, Shimada A, Gross L, Hyatt C, Kelly W, Calvaresi A, Handley N, Hirsch I, Izes J, Lallas C, Mann M, Mark J, Mille P, Preate D, Trabulsi E, Tsang M, Chandrasekar T, Weiner P, Gomella L, Giri V. Pretest Genetic Education Video Versus Genetic Counseling for Men Considering Prostate Cancer Germline Testing: A Patient-Choice Study to Address Urgent Practice Needs. JCO Precision Oncology 2021, 5: 1377-1386. PMID: 34589662, PMCID: PMC8462590, DOI: 10.1200/po.21.00238.Peer-Reviewed Original ResearchConceptsGermline testingProstate cancerGenetic counselingDecisional conflictComparable patient-reported outcomesHereditary cancer assessmentPatient-reported outcomesCancer genetics knowledgePCa diagnosisPractice settingsPrecision careCancer assessmentInformed consentCategorical variablesSubstantial proportionGenetic knowledgeSignificant differencesContinuous variablesHigh rateMenPractice needsDescriptive statisticsProstate oncologyOutcomesCounselingGenetic Testing Guidelines and Education of Health Care Providers Involved in Prostate Cancer Care
Mark J, McDougall C, Giri V. Genetic Testing Guidelines and Education of Health Care Providers Involved in Prostate Cancer Care. Urologic Clinics Of North America 2021, 48: 311-322. PMID: 34210487, DOI: 10.1016/j.ucl.2021.03.003.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsGermline testingProstate cancerGenetic testing guidelinesFirst-line therapyCastration-resistant diseaseEarly-stage diseaseProstate cancer careHealth care providersGenetic test resultsPCA careCancer careCare providersScreening settingCancer implicationsPARP inhibitorsTesting guidelinesPossible roleDiseaseCareMenPractice strategiesOncologistsTestingTherapyCancer
2020
Video vs. in-person genetic counseling for men considering germline prostate cancer testing: A patient-choice study.
Giri V, Bowler N, Hegarty S, Gross L, Hyatt C, Kelly W, Gomella L. Video vs. in-person genetic counseling for men considering germline prostate cancer testing: A patient-choice study. Journal Of Clinical Oncology 2020, 38: 1577-1577. DOI: 10.1200/jco.2020.38.15_suppl.1577.Peer-Reviewed Original ResearchCancer genetics knowledgeGermline testingPerson genetic counselingProstate cancerGenetic counselingBaseline anxietyDecisional conflictPatient-reported outcomesAfrican American raceProstate cancer testingHigh baseline anxietyLow educational levelFisher's exactFamily historyPCa diagnosisCancer testingAmerican raceCategorical variablesFirst cohortPathogenic mutationsLow knowledgeSAS 9.4Chi-squaredSubstantial proportionMen
2018
Understanding of multigene test results among males undergoing germline testing for inherited prostate cancer: Implications for genetic counseling
Giri V, Obeid E, Hegarty S, Gross L, Bealin L, Hyatt C, Fang C, Leader A. Understanding of multigene test results among males undergoing germline testing for inherited prostate cancer: Implications for genetic counseling. The Prostate 2018, 78: 879-888. PMID: 29655297, PMCID: PMC6047906, DOI: 10.1002/pros.23535.Peer-Reviewed Original ResearchConceptsInherited prostate cancerProstate cancerGenetic counselingGenetic testingMultivariable linear regressionFamily history dataPre-test genetic counselingHigh baseline knowledgeSyndrome criteriaGermline testingMultivariable analysisMultigene testingMedical recordsFamily historyCancer riskSubset of malesMcNemar testUncertain significanceGEM participantsHigher knowledgeMeasures of knowledgeGenetic resultsMenGT resultsBaseline knowledgeThe Frequency of CHEK2 variant p.Ile157Thr in Men with Prostate Cancer: Towards Expanded Genetic Testing
Agubokwu N, Giri V. The Frequency of CHEK2 variant p.Ile157Thr in Men with Prostate Cancer: Towards Expanded Genetic Testing. The FASEB Journal 2018, 32: 532.9-532.9. DOI: 10.1096/fasebj.2018.32.1_supplement.532.9.Peer-Reviewed Original Research
2016
Effects of a randomized trial comparing standard and enhanced counseling for men at high risk of prostate cancer as a function of race and monitoring style
Roussi P, Miller S, Giri V, Obeid E, Wen K, Tagai E, Scarpato J, Gross L, Roy G. Effects of a randomized trial comparing standard and enhanced counseling for men at high risk of prostate cancer as a function of race and monitoring style. Journal Of Health Psychology 2016, 23: 1800-1809. PMID: 28810355, PMCID: PMC5561513, DOI: 10.1177/1359105316671188.Peer-Reviewed Original ResearchConceptsProstate cancer screeningHigh-risk menCancer screeningProstate Cancer Risk Assessment ProgramRoutine prostate cancer screeningCancer Risk Assessment ProgramHealth education sessionsCounseling visitsEnhanced counselingProstate cancerHigh riskEducation sessionsRisk assessment programPsychosocial impactCounseling conditionMenSelf-selected sampleFunction of raceSignificant subsetRiskIntrusive ideationInterventionCounselingScreeningMonitoring styleDecision Support and Shared Decision Making About Active Surveillance Versus Active Treatment Among Men Diagnosed with Low-Risk Prostate Cancer: a Pilot Study
Myers R, Leader A, Censits J, Trabulsi E, Keith S, Petrich A, Quinn A, Den R, Hurwitz M, Lallas C, Hegarty S, Dicker A, Zeigler-Johnson C, Giri V, Ayaz H, Gomella L. Decision Support and Shared Decision Making About Active Surveillance Versus Active Treatment Among Men Diagnosed with Low-Risk Prostate Cancer: a Pilot Study. Journal Of Cancer Education 2016, 33: 180-185. PMID: 27418065, DOI: 10.1007/s13187-016-1073-7.Peer-Reviewed Original ResearchConceptsLow-risk prostate cancerActive surveillanceProstate cancerDecision support interventionsActive treatmentDecisional conflictClinic visitsTreatment choiceClinician supportTreatment knowledgePatient choiceSupport interventionsBaseline surveyPilot studyCancerMenTreatmentParticipantsSurveillancePatientsFollowCliniciansSDMVisits
2015
Lessons Learned from Implementing a Prostate Cancer Risk Assessment Program for Underserved High-Risk Men in the Community: the Prostate REACH Project
Fleisher L, Davis S, Gross L, Bagden L, Zakrzewski D, González E, Kandadai V, Rusten C, Baskett J, Obeid E, Giri V. Lessons Learned from Implementing a Prostate Cancer Risk Assessment Program for Underserved High-Risk Men in the Community: the Prostate REACH Project. Journal Of Cancer Education 2015, 31: 191-197. PMID: 25971432, DOI: 10.1007/s13187-015-0854-8.Peer-Reviewed Original ResearchConceptsProstate Cancer Risk Assessment ProgramCancer Risk Assessment ProgramRisk assessment programProstate cancerProstate cancer risk assessmentRisk assessment clinicComprehensive cancer centerCommunity-based promotionCancer risk assessmentProstate riskREACH projectUnderserved menAssessment clinicCancer CenterClinic sitesUninsured menAbnormal resultsKey implementation stepsRisk menUnique demonstration projectNavigator servicesAssessment ProgramMenCancerBlack menInterest in genomic SNP testing for prostate cancer risk: a pilot survey
Hall M, Ruth K, Chen D, Gross L, Giri V. Interest in genomic SNP testing for prostate cancer risk: a pilot survey. Hereditary Cancer In Clinical Practice 2015, 13: 11. PMID: 25874018, PMCID: PMC4396119, DOI: 10.1186/s13053-015-0032-3.Peer-Reviewed Original ResearchProstate cancer riskProstate Cancer Risk Assessment ProgramCancer riskHealth literacySNP testingCancer Risk Assessment ProgramSingle nucleotide polymorphismsHigher health literacyHigh-risk menHigh-risk statusNovel genomic testsPredictors of interestOne-time surveyUrology clinicProstate cancerMultivariable modelingClinical utilityPsychosocial factorsRisk assessment programGenomic testingGenomic testsUnsolicited findingsLow literacyRiskMen
2014
Prostate cancer early detection, version 1.2014. Featured updates to the NCCN Guidelines.
Carroll P, Parsons J, Andriole G, Bahnson R, Barocas D, Catalona W, Dahl D, Davis J, Epstein J, Etzioni R, Giri V, Hemstreet G, Kawachi M, Lange P, Loughlin K, Lowrance W, Maroni P, Mohler J, Morgan T, Nadler R, Poch M, Scales C, Shanefelt T, Vickers A, Wake R, Shead D, Ho M. Prostate cancer early detection, version 1.2014. Featured updates to the NCCN Guidelines. Journal Of The National Comprehensive Cancer Network 2014, 12: 1211-9; quiz 1219. PMID: 25190691, DOI: 10.6004/jnccn.2014.0120.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsProstate cancer early detectionCancer early detectionNCCN guidelinesProstate cancerEarly detectionNCCN Guidelines InsightsNotable recent updatesProstate Health IndexEarly Detection ProgramRecent FDA approvalMultiple risk variablesBiopsy decisionsFDA approvalDetection programRisk variablesCancerHealth indexRecent updatesMenGuidelinesBiopsy
2013
Global Patterns of Prostate Cancer Incidence, Aggressiveness, and Mortality in Men of African Descent
Rebbeck T, Devesa S, Chang B, Bunker C, Cheng I, Cooney K, Eeles R, Fernandez P, Giri V, Gueye S, Haiman C, Henderson B, Heyns C, Hu J, Ingles S, Isaacs W, Jalloh M, John E, Kibel A, Kidd L, Layne P, Leach R, Neslund-Dudas C, Okobia M, Ostrander E, Park J, Patrick A, Phelan C, Ragin C, Roberts R, Rybicki B, Stanford J, Strom S, Thompson I, Witte J, Xu J, Yeboah E, Hsing A, Zeigler-Johnson C. Global Patterns of Prostate Cancer Incidence, Aggressiveness, and Mortality in Men of African Descent. Prostate Cancer 2013, 2013: 560857. PMID: 23476788, PMCID: PMC3583061, DOI: 10.1155/2013/560857.Peer-Reviewed Original ResearchCAP incidenceSignificant public health problemProstate cancer incidenceAfrican descentPublic health problemLower mortality rateSub-Saharan AfricaHigher proportionAdvanced tumorsTumor stageCancer incidenceProstate cancerMortality rateProstate tumorsCancer ConsortiumHealth problemsMortalityIncidenceHealth careMenPercent gross domestic productAfrican AmericansTumorsCancerEstimated number
2004
Association between Agent Orange and prostate cancer: a pilot case-control study
Giri V, Cassidy A, Beebe-Dimmer J, Ellis L, Smith D, Bock C, Cooney K. Association between Agent Orange and prostate cancer: a pilot case-control study. Urology 2004, 63: 757-760. PMID: 15072895, DOI: 10.1016/j.urology.2003.11.044.Peer-Reviewed Original ResearchMeSH Keywords2,4-Dichlorophenoxyacetic Acid2,4,5-Trichlorophenoxyacetic AcidAgent OrangeCase-Control StudiesDefoliants, ChemicalEnvironmental ExposureHumansMaleMedical Records Systems, ComputerizedMichiganMiddle AgedPilot ProjectsPolychlorinated DibenzodioxinsProstateProstatic NeoplasmsRisk FactorsVeteransVietnamWarfareConceptsCase-control studyProstate cancerPilot case-control studyAgent OrangeVeterans Affairs Medical CenterPilot studyMilitary veteransComputerized medical recordsClinical featuresCancer deathCommon cancerControl menMedical recordsMedical CenterEpidemiologic studiesCancerPrevious exposureAdditional studiesAmerican menClinical populationsMenExposureAssociationAgeVeterans