2022
Germline Variant Spectrum Among African American Men Undergoing Prostate Cancer Germline Testing: Need for Equity in Genetic Testing
Giri V, Hartman R, Pritzlaff M, Horton C, Keith S. Germline Variant Spectrum Among African American Men Undergoing Prostate Cancer Germline Testing: Need for Equity in Genetic Testing. JCO Precision Oncology 2022, 6: e2200234. PMID: 35666082, PMCID: PMC9200399, DOI: 10.1200/po.22.00234.Peer-Reviewed Original ResearchConceptsGermline testingAA menWhite menHereditary cancer assessmentStandard clinical testingCohort of menAfrican American menGermline evaluationMultivariable analysisClinical managementBorderline associationLP variantsVariant statusClinical testingGermline analysisPanel testingRate of variantsCare deliveryVariant spectrumGenetic testingCancer assessmentUncertain significanceDNA repair genesGenetic counselingAmerican men
2020
The effect of neighborhood social environment on prostate cancer development in black and white men at high risk for prostate cancer
Lynch S, Handorf E, Sorice K, Blackman E, Bealin L, Giri V, Obeid E, Ragin C, Daly M. The effect of neighborhood social environment on prostate cancer development in black and white men at high risk for prostate cancer. PLOS ONE 2020, 15: e0237332. PMID: 32790761, PMCID: PMC7425919, DOI: 10.1371/journal.pone.0237332.Peer-Reviewed Original ResearchConceptsProstate-specific antigenPCa family historyHigh-risk menProbability of PCaFamily historyPCa diagnosisRisk menWhite menDigital rectal examEarly Detection ProgramClinical risk assessmentProstate cancer disparitiesProstate cancer developmentPatient risk assessmentNeighborhood socioeconomic factorsPatient-level modelsCox regressionRectal examBaseline ageCancer disparitiesPatient variablesProstate cancerHigh riskNeighborhood social environmentClinical relevance