1981
Multimodal treatment of primary breast carcinoma Analysis of accomplishments and problem areas
Weiss R, Henney J, DeVita V. Multimodal treatment of primary breast carcinoma Analysis of accomplishments and problem areas. The American Journal Of Medicine 1981, 70: 844-851. PMID: 7011024, DOI: 10.1016/0002-9343(81)90541-6.Peer-Reviewed Original ResearchConceptsAxillary nodesInvolved axillary nodesDisease-free survivalUse of chemotherapyBreast carcinoma patientsCertain patient groupsFuture clinical trialsPrimary breast carcinomaBetter therapeutic indexMurine tumor modelsCarcinoma patientsDrug regimensMultimodal treatmentPatient groupClinical trialsBreast carcinomaBreast cancerTherapeutic indexChemotherapy modePatientsSpecific subgroupsTumor modelMastectomyChemotherapyHuman subjects
1974
Cyclical Combination Chemotherapy for Advanced Breast Carcinoma
Canellos G, Devita V, Gold G, Chabner B, Schein P, Young R. Cyclical Combination Chemotherapy for Advanced Breast Carcinoma. The BMJ 1974, 1: 218. PMID: 4818162, PMCID: PMC1633086, DOI: 10.1136/bmj.1.5901.218.Peer-Reviewed Original ResearchConceptsMedian survivalMetastatic lesionsAdvanced metastatic breast cancerCyclical combination chemotherapyOverall median durationAdvanced breast carcinomaBone marrow involvementMetastatic breast cancerMetastasis-free intervalSoft tissueExtensive radiotherapyPrevious chemotherapyComplete remissionHaematological toxicityHormonal therapyLiver dysfunctionMarrow involvementMedian durationCombination chemotherapyEndocrine ablationBreast carcinomaBreast cancerPatientsMonthly cyclesChemotherapy