1985
Abnormal coagulation results in patients with hodgkin's disease
Seifter E, Parker R, Gralnick H, Wesley M, DeVita V, Young R, Longo D. Abnormal coagulation results in patients with hodgkin's disease. The American Journal Of Medicine 1985, 78: 942-950. PMID: 3160235, DOI: 10.1016/0002-9343(85)90216-5.Peer-Reviewed Original ResearchConceptsHodgkin's diseaseProthrombin timeAbnormal coagulation test resultsAbnormal coagulation resultsAbnormal test valuesComplete staging evaluationProthrombin time prolongationCoagulation test resultsCourse of diseaseCoagulation factor disordersPartial thromboplastin timeAlkaline phosphatase levelsClotting abnormalitiesAdvanced diseaseConstitutional symptomsMediastinal involvementStaging evaluationCoagulation abnormalitiesAbnormal coagulationEvaluable casesTumor regressionThromboplastin timeFactor disordersHematologic testingInvasive procedures
1976
A Phase I–II Trial of Multiple-Dose Polyriboinosinic-Polyribocytidylic Acid in Patients With Leukemia or Solid Tumors
Robinson R, DeVita V, Levy H, Baron S, Hubbard S, Levine A. A Phase I–II Trial of Multiple-Dose Polyriboinosinic-Polyribocytidylic Acid in Patients With Leukemia or Solid Tumors. Journal Of The National Cancer Institute 1976, 57: 599-602. PMID: 978771, DOI: 10.1093/jnci/57.3.599.Peer-Reviewed Original ResearchConceptsSolid tumorsSerum glutamic oxaloacetic transaminaseSerum glutamic pyruvic transaminaseSeparate drug trialsObjective tumor responseDetectable serum levelsRoute of administrationChronic myelogenous leukemiaLow serum concentrationsGlutamic oxaloacetic transaminaseGlutamic pyruvic transaminasePolyriboinosinic-polyribocytidylic acidPoly I-poly CInducers of interferonCoagulation abnormalitiesSerum levelsMultiple dosesSerum concentrationsTumor responseAcute leukemiaDrug trialsBlast crisisMyelogenous leukemiaTransient elevationDrug dose