Chemotherapy of the blastic phase of chronic granulocytic leukemia: hypodiploidy and response to therapy.
Canellos G, DeVita V, Whang-Peng J, Chabner B, Schein P, Young R. Chemotherapy of the blastic phase of chronic granulocytic leukemia: hypodiploidy and response to therapy. Blood 1976, 47: 1003-9. PMID: 1064434, DOI: 10.1182/blood.v47.6.1003.bloodjournal4761003.Peer-Reviewed Original ResearchConceptsChromosome-positive chronic granulocytic leukemiaChronic granulocytic leukemiaBlastic phaseComplete remissionPrior splenectomyComplete remittersGranulocytic leukemiaCytosine arabinosidePhiladelphia chromosome-positive chronic granulocytic leukemiaNonsplenectomized groupPrednisone groupPartial remissionMedian survivalElective splenectomyPartial responseSecondary therapyChronic phaseOpposite regimenRemissionSplenectomyVincristinePrednisoneChemotherapyPatientsCell linesChemotherapy of the Blastic Phase of Chronic Granulocytic Leukemia: Hypodiploidy and Response to Therapy
Canellos G, DeVita V, Whang-Peng J, Chabner B, Schein P, Young R. Chemotherapy of the Blastic Phase of Chronic Granulocytic Leukemia: Hypodiploidy and Response to Therapy. Blood 1976, 47: 1003-1009. DOI: 10.1182/blood.v47.6.1003.1003.Peer-Reviewed Original ResearchChromosome-positive chronic granulocytic leukemiaChronic granulocytic leukemiaBlastic phaseComplete remissionPrior splenectomyComplete remittersGranulocytic leukemiaCytosine arabinosidePhiladelphia chromosome-positive chronic granulocytic leukemiaNonsplenectomized groupPrednisone groupPartial remissionMedian survivalElective splenectomyPartial responseSecondary therapyChronic phaseOpposite regimenRemissionPrednisoneVincristineSplenectomyChemotherapyPatientsCell linesEffect of splenectomy on tolerance to combination chemotherapy in patients with lymphoma.
Ihde D, DeVita V, Canellos G, Young R. Effect of splenectomy on tolerance to combination chemotherapy in patients with lymphoma. Blood 1976, 47: 211-22. PMID: 1244920, DOI: 10.1182/blood.v47.2.211.bloodjournal472211.Peer-Reviewed Original ResearchConceptsTolerance to combination chemotherapyCombination chemotherapyHodgkin's diseasePlatelet countControl patientsBone marrow lymphomaSplenectomy per seCycles of therapyNon-Hodgkin's lymphomaCycles of treatmentMatched control patientsPortion of patientsEffect of splenectomyLymphoma patientsInitial treatmentStaging procedureLymphomaTotal doseSplenectomyChemotherapyLeukocyte countPatientsHodgkinLeukocytesPlateletEffect of Splenectomy on Tolerance to Combination Chemotherapy in Patients With Lymphoma
Ihde D, DeVita V, Canellos G, Young R. Effect of Splenectomy on Tolerance to Combination Chemotherapy in Patients With Lymphoma. Blood 1976, 47: 211-222. DOI: 10.1182/blood.v47.2.211.211.Peer-Reviewed Original ResearchTolerance to combination chemotherapyCombination chemotherapyHodgkin's diseasePlatelet countControl patientsBone marrow lymphomaSplenectomy per seCycles of therapyCycles of treatmentMatched control patientsPortion of patientsEffect of splenectomyHodgkin lymphomaLymphoma patientsInitial treatmentStaging procedureLymphomaTotal doseSplenectomyChemotherapyLeukocyte countHodgkinPatientsLeukocytesPlateletSplenectomy in the chronic phase of chronic granulocytic leukemia. Effects in 32 patients.
Ihde D, Canellos G, Schwartz J, DeVita V. Splenectomy in the chronic phase of chronic granulocytic leukemia. Effects in 32 patients. Annals Of Internal Medicine 1976, 84: 17-21. PMID: 1060395, DOI: 10.7326/0003-4819-84-1-17.Peer-Reviewed Original ResearchConceptsChronic phase of chronic granulocytic leukemiaPhase of chronic granulocytic leukemiaChronic granulocytic leukemiaChronic phaseGranulocytic leukemiaPhiladelphia chromosome-positive patientsSurvival of patientsYear of diagnosisChronic phase of diseasePhase of diseaseMedian survivalProphylactic splenectomySplenectomy patientsPlatelet transfusionsElective splenectomyAdequate therapyMassive splenomegalyBlastic transformationEarly diseaseSplenectomyInfluence survivalPatientsStage of illnessLeukemiaSurvival