1979
Central nervous system complications of non-Hodgkin's lymphoma The potential role for prophylactic therapy
Young R, Howser D, Anderson T, Fisher R, Jaffe E, DeVita V. Central nervous system complications of non-Hodgkin's lymphoma The potential role for prophylactic therapy. The American Journal Of Medicine 1979, 66: 435-443. PMID: 433950, DOI: 10.1016/0002-9343(79)91065-9.Peer-Reviewed Original ResearchConceptsCentral nervous systemCNS diseaseHodgkin's lymphomaCentral nervous system complicationsNervous system complicationsWhole-brain irradiationGood clinical responseBone marrow involvementTime of diagnosisGroup of patientsAdvanced diseaseBrain irradiationClinical remissionCNS prophylaxisIntrathecal chemotherapyLymphomatous meningitisProphylactic therapyClinical responseMarrow involvementPositive cytologyMalignant lymphomaSystem complicationsLumbar punctureNodular lymphomaRisk factors
1972
Nonlymphomatous Malignant Tumors Complicating Hodgkin's Disease — Possible Association with Intensive Therapy
Arseneau J, Sponzo R, Levin D, Schnipper L, Bonner H, Young R, Canellos G, Johnson R, DeVita V. Nonlymphomatous Malignant Tumors Complicating Hodgkin's Disease — Possible Association with Intensive Therapy. New England Journal Of Medicine 1972, 287: 1119-1122. PMID: 5082192, DOI: 10.1056/nejm197211302872204.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAntineoplastic AgentsCarcinoma, Squamous CellCyclophosphamideDrug-Related Side Effects and Adverse ReactionsFemaleFibrosarcomaFollow-Up StudiesHead and Neck NeoplasmsHodgkin DiseaseHumansMaleMiddle AgedNeoplasm MetastasisNeoplasmsNeoplasms, Radiation-InducedNitrogen Mustard CompoundsPrednisoneProcarbazineRadiotherapyRemission, SpontaneousTime FactorsVincristineConceptsHodgkin's diseaseMalignant tumorsIntensive radiotherapyIntensive chemotherapyBiopsy-proven malignant tumorsTime of diagnosisSecond malignant tumorsRisk of developmentBasis of treatmentBasis of ageIntensive therapyCase recordsChemotherapyDiseasePatientsRadiotherapyTumorsGreater increaseSubgroupsRiskTherapyIncidenceDiagnosisPhytohemagglutinin-induced Lymphocyte Transformation: The Relationship to Prognosis of Hodgkin's Disease
Corder M, Young R, Brown R, DeVita V. Phytohemagglutinin-induced Lymphocyte Transformation: The Relationship to Prognosis of Hodgkin's Disease. Blood 1972, 39: 595-601. PMID: 5022714, DOI: 10.1182/blood.v39.5.595.595.Peer-Reviewed Original ResearchDelayed hypersensitivity in Hodgkin's disease A study of 103 untreated patients
Young R, Corder M, Haynes H, DeVita V. Delayed hypersensitivity in Hodgkin's disease A study of 103 untreated patients. The American Journal Of Medicine 1972, 52: 63-72. PMID: 5058359, DOI: 10.1016/0002-9343(72)90008-3.Peer-Reviewed Original ResearchConceptsSkin test reactivityPeripheral lymphocyte countTest reactivityHodgkin's diseaseLymphocyte countUntreated patientsPrognostic signSkin testAbsolute peripheral lymphocyte countLymphocyte-depleted Hodgkin's diseaseMean absolute lymphocyte countIncidence of anergyStage IV diseaseAbsolute lymphocyte countBad prognostic signDuration of remissionFrequency of relapsesTime of diagnosisStage of diseaseUseful prognostic signCutaneous anergyPeripheral lymphocytopeniaMixed cellularityMumps antigenNodular sclerosis