1976
Effect of Splenectomy on Tolerance to Combination Chemotherapy in Patients With Lymphoma
Ihde D, DeVita V, Canellos G, Young R. Effect of Splenectomy on Tolerance to Combination Chemotherapy in Patients With Lymphoma. Blood 1976, 47: 211-222. DOI: 10.1182/blood.v47.2.211.211.Peer-Reviewed Original ResearchTolerance to combination chemotherapyCombination chemotherapyHodgkin's diseasePlatelet countControl patientsBone marrow lymphomaSplenectomy per seCycles of therapyCycles of treatmentMatched control patientsPortion of patientsEffect of splenectomyHodgkin lymphomaLymphoma patientsInitial treatmentStaging procedureLymphomaTotal doseSplenectomyChemotherapyLeukocyte countHodgkinPatientsLeukocytesPlateletEffect of splenectomy on tolerance to combination chemotherapy in patients with lymphoma.
Ihde D, DeVita V, Canellos G, Young R. Effect of splenectomy on tolerance to combination chemotherapy in patients with lymphoma. Blood 1976, 47: 211-22. PMID: 1244920, DOI: 10.1182/blood.v47.2.211.bloodjournal472211.Peer-Reviewed Original ResearchConceptsTolerance to combination chemotherapyCombination chemotherapyHodgkin's diseasePlatelet countControl patientsBone marrow lymphomaSplenectomy per seCycles of therapyNon-Hodgkin's lymphomaCycles of treatmentMatched control patientsPortion of patientsEffect of splenectomyLymphoma patientsInitial treatmentStaging procedureLymphomaTotal doseSplenectomyChemotherapyLeukocyte countPatientsHodgkinLeukocytesPlatelet
1974
Clinical antitumor activity and toxicity of streptozotocin (NSC‐85998)
Schein P, O'Connell M, Blom J, Hubbard S, Magrath I, Bergevin P, Wiernik P, Ziegler J, Devita V. Clinical antitumor activity and toxicity of streptozotocin (NSC‐85998). Cancer 1974, 34: 993-1000. PMID: 4371075, DOI: 10.1002/1097-0142(197410)34:4<993::aid-cncr2820340404>3.0.co;2-t.Peer-Reviewed Original ResearchConceptsMalignant carcinoid tumorsNormal renal functionIslet cell carcinomaClinical antitumor activityAcute lymphocytic leukemiaToxicity of streptozotocinHematologic toxicityAdvanced malignanciesRenal damageRenal functionCarcinoid tumorsHodgkin's diseaseCell carcinomaLymphocytic lymphomaTherapeutic responseLymphocytic leukemiaTumor massBurkitt's lymphomaDrug effectsMaximum dosesPatientsTotal doseStreptozotocinLymphomaAntitumor activity