2024
Conservative versus liberal oxygen therapy for intensive care unit patients: meta-analysis of randomized controlled trials
Li X, Dai B, Hou H, Zhao H, Wang W, Kang J, Tan W. Conservative versus liberal oxygen therapy for intensive care unit patients: meta-analysis of randomized controlled trials. Annals Of Intensive Care 2024, 14: 68. PMID: 38668955, PMCID: PMC11052962, DOI: 10.1186/s13613-024-01300-7.Peer-Reviewed Original ResearchIntensive care unit patientsLiberal oxygen therapyConservative oxygen therapyIntensive care unitRandomized controlled trialsHospital length of stayLength of stayOxygen therapyControlled trialsClinical outcomesHospital lengthMeta-analysis of randomized controlled trialsClinical outcomes of ICU patientsIntensive care unit length of stayIntensive care unit lengthOutcomes of ICU patientsCochrane Central Register of Controlled TrialsMeta-analysisCentral Register of Controlled TrialsMethodsWe systematically searched PubMedMechanical ventilation supportRegister of Controlled TrialsOutcomes of intensive care unitCochrane Central RegisterSystematically searched PubMed
2022
Comparison between high-flow nasal cannula and noninvasive ventilation in COVID-19 patients: a systematic review and meta-analysis
Peng Y, Dai B, Zhao H, Wang W, Kang J, Hou H, Tan W. Comparison between high-flow nasal cannula and noninvasive ventilation in COVID-19 patients: a systematic review and meta-analysis. Therapeutic Advances In Respiratory Disease 2022, 16: 17534666221113663. PMID: 35861299, PMCID: PMC9340323, DOI: 10.1177/17534666221113663.Peer-Reviewed Original ResearchConceptsHigh-flow nasal cannulaAcute hypoxemic respiratory failureHigh-flow nasal cannula groupIntensive care unitClinical outcomes of COVID-19Noninvasive ventilation groupNoninvasive ventilationInvasive mechanical ventilationRandomized controlled trialsOutcomes of COVID-19Intubation rateNasal cannulaClinical outcomesCOVID-19-related acute hypoxemic respiratory failureMechanical ventilationHospital LOSPositive airway pressureHypoxemic respiratory failureMortality rateIntensive care unit LOSMeta-analysisSystematic reviewCPAP groupCOVID-19 patientsAirway pressure
2021
The Use of Aerosolized Medications in Adult Intensive Care Unit Patients: A Prospective, Multicenter, Observational, Cohort Study
Lyu S, Li J, Wu M, He D, Fu T, Ni F, Tan X, Wu G, Pan B, Li L, Wang H, Zeng G, Ni Z, Tan W, Zong Y, Chen L, Liu P, Qin H, He P, Zhang L, An Y, Liang Z, Xie L, Li Y, Zhou M, Li Q, Zhao J, Fang B, Ma Y, Huang R, Guo W, Dong X, Huang X, MO G, Xia J, Xiao K, Zhao H, Kong X, Zhao H, Ma J, Gao P, Yang W, Han F, Dong Y, Ye L, Chen C, Bao Z, Liu Y, Zheng C, Miao L, Yao M, Wang W, Wei S, Li H, Luo F, Liang G, Li J, Zhang C, Dai L, Song L, Wang C, Wang S. The Use of Aerosolized Medications in Adult Intensive Care Unit Patients: A Prospective, Multicenter, Observational, Cohort Study. Journal Of Aerosol Medicine And Pulmonary Drug Delivery 2021, 34: 383-391. PMID: 34129389, DOI: 10.1089/jamp.2021.0004.Peer-Reviewed Original ResearchConceptsIntensive care unitAerosol therapyAerosolized medicationsCohort studySide effectsShort-acting muscarinic antagonistsCombination of inhaled corticosteroidsChronic obstructive pulmonary disease exacerbationsIntensive care unit patientsSpontaneously breathing patientsAdult intensive care unit patientsAdult ICU patientsChinese ICUsBreathing patientsRespiratory supportMuscarinic antagonistInhaled corticosteroidsAdult patientsClinical outcomesMechanical ventilationDisease exacerbationUnit patientsCare unitConclusion:</i></b>ICU patients
2017
Multiregion sequencing of penile cancer to reveal distinct patterns of heterogeneous actionable mutations.
Rodney S, Tanic M, Barrett J, Amy W, de Winter P, Tan W, Khetrapal P, Dong L, Rezaee S, Freeman A, Nigam R, Malone P, Muneer A, Beck S, Feber A, Kelly J. Multiregion sequencing of penile cancer to reveal distinct patterns of heterogeneous actionable mutations. Journal Of Clinical Oncology 2017, 35: 4518-4518. DOI: 10.1200/jco.2017.35.15_suppl.4518.Peer-Reviewed Original ResearchLymph node metastasisPenile cancerCopy number changesNode metastasisIntra-tumor heterogeneityActionable mutationsCases of HPV infectionOutcome of metastatic diseaseHuman papillomavirus infectionPotential of immunotherapyTyrosine kinase inhibitorsInter-tumor heterogeneityMutation loadAcquisition of mutationsDeep whole-exome sequencingEarly eventWhole-exome sequencingHPV infectionMetastatic diseaseHuman papillomavirusPapillomavirus infectionClinical outcomesMultiregional sequencingMutated PIK3CAMetastatic tissues