2022
A systematic review and meta-analysis on delaying surgery for urothelial carcinoma of bladder and upper tract urothelial carcinoma: Implications for the COVID19 pandemic and beyond
Leow J, Tan W, Tan W, Tan T, Chan V, Tikkinen K, Kamat A, Sengupta S, Meng M, Shariat S, Roupret M, Decaestecker K, Vasdev N, Chong Y, Enikeev D, Giannarini G, Ficarra V, Teoh J, Collaborators O. A systematic review and meta-analysis on delaying surgery for urothelial carcinoma of bladder and upper tract urothelial carcinoma: Implications for the COVID19 pandemic and beyond. Frontiers In Surgery 2022, 9: 879774. PMID: 36268209, PMCID: PMC9577485, DOI: 10.3389/fsurg.2022.879774.Peer-Reviewed Original ResearchRadical nephro-ureterectomyAssociated with poor overall survivalRadical cystectomyNeoadjuvant chemotherapyPoor overall survivalOverall survivalUrothelial carcinomaSurvival outcomesUrothelial carcinoma of bladderAssociated with poor survival outcomesUpper tract urothelial carcinomaAssociated with overall survivalDiagnosis of UCBCancer-specific survivalInvasive urothelial carcinomaCarcinoma of bladderUrologic cancer surgeryMeta-analysisPoor survival outcomesSystematic reviewDefinitive surgeryBetween-study heterogeneityDelayed surgeryNephro-ureterectomyUpper tract
2021
Delayed surgery for localised and metastatic renal cell carcinoma: a systematic review and meta-analysis for the COVID-19 pandemic
Chan V, Tan W, Leow J, Tan W, Ong W, Chiu P, Gurung P, Pirola G, Orecchia L, Liew M, Lee H, Wang Y, Chen I, Castellani D, Wroclawski M, Mayor N, Sathianathen N, Braga I, Liu Z, Moon D, Tikkinen K, Kamat A, Meng M, Ficarra V, Giannarini G, Teoh J. Delayed surgery for localised and metastatic renal cell carcinoma: a systematic review and meta-analysis for the COVID-19 pandemic. World Journal Of Urology 2021, 39: 4295-4303. PMID: 34031748, PMCID: PMC8143063, DOI: 10.1007/s00345-021-03734-1.Peer-Reviewed Original ResearchConceptsMetastatic renal cell carcinomaRenal cell carcinomaLocalised RCCDelayed surgeryCytoreductive nephrectomyDeferred CNOverall survivalCell carcinomaTargeted therapyAssociated with worse cancer-specific survivalAssociated with better overall survivalT1a renal cell carcinomaEffect of delaying surgeryDeferred cytoreductive nephrectomyCancer-specific survivalMeta-analysisElective cancer surgeryNewcastle-Ottawa ScaleSystematic reviewComprehensive literature searchUpfront CNOncological effectivenessRisk of biasImmediate surgeryRandomised controlled trials