2023
PD13-12 BLADDER SPARING TREATMENT IN PATIENTS WITH BCG UNRESPONSIVE NON-MUSCLE INVASIVE BLADDER CANCER: AN ANALYSIS OF LONG-TERM SURVIVAL OUTCOMES
Tan W, Grajales V, Contieri R, Hensley P, Bree K, Msaouel P, Guo C, Navai N, Dinney C, Kamat A. PD13-12 BLADDER SPARING TREATMENT IN PATIENTS WITH BCG UNRESPONSIVE NON-MUSCLE INVASIVE BLADDER CANCER: AN ANALYSIS OF LONG-TERM SURVIVAL OUTCOMES. Journal Of Urology 2023, 209: e410. DOI: 10.1097/ju.0000000000003260.12.Peer-Reviewed Original ResearchThe effects of flow settings during high-flow nasal cannula support for adult subjects: a systematic review
Li J, Albuainain F, Tan W, Scott J, Roca O, Mauri T. The effects of flow settings during high-flow nasal cannula support for adult subjects: a systematic review. Critical Care 2023, 27: 78. PMID: 36855198, PMCID: PMC9974062, DOI: 10.1186/s13054-023-04361-5.Peer-Reviewed Original ResearchConceptsHigh-flow nasal cannulaHigh-flow nasal cannula treatmentIn vivo studiesPatient's peak inspiratory flowHigh-flow nasal cannula supportFraction of inspired oxygenPositive end-expiratory pressurePeak inspiratory flowSystematic reviewEnd-expiratory pressureDead space washoutNon-dependent lung regionsIn vitro studiesRisk of biasROX indexNasal cannulaClinical findingsImprove oxygenationPediatric populationPatient discomfortAlveolar overdistentionInspiratory flowWeb of SciencePatient comfortPatients
2021
Current application of the enhanced recovery after surgery protocol for patients undergoing radical cystectomy: lessons learned from European excellence centers
Albisinni S, Moschini M, Di Trapani E, Soria F, Mari A, Aziz A, Teoh J, Laukhtina E, Mori K, D’Andrea D, Carrion D, Krajewski W, Abufaraj M, Cimadamore A, Tan W, Flippot R, Khalifa J, Gonsette K, Pradere B. Current application of the enhanced recovery after surgery protocol for patients undergoing radical cystectomy: lessons learned from European excellence centers. World Journal Of Urology 2021, 40: 1317-1323. PMID: 34076754, DOI: 10.1007/s00345-021-03746-x.Peer-Reviewed Original ResearchConceptsOpioid-sparing anesthesiaRadical cystectomyERAS implementationPreoperative carbohydrate loadingEuropean expert centersImplementation of ERASBowel preparationERAS itemsRC patientsSurgery protocolExpert centersNasogastric tubeEarly mobilizationCarbohydrate loadingImplementing ERASEligibility criteriaCystectomyEnhanced recoverySurgeonsSurgeryAnesthesiologistsPatientsAnesthesiaERAS SocietyExcellence centersIs delay to radical cystectomy following BCG failure oncologically safe?
Tan W, Kelly J. Is delay to radical cystectomy following BCG failure oncologically safe? Nature Reviews Urology 2021, 18: 323-324. PMID: 33772157, DOI: 10.1038/s41585-021-00457-1.Peer-Reviewed Original Research
2020
Delayed blood transfusion is associated with mortality following radical cystectomy
Tan W, Wang Y, Trinh Q, Preston M, Kelly J, Hrouda D, Kibel A, Krasnow R, Liu J, Chung B, Chang S, Mossanen M. Delayed blood transfusion is associated with mortality following radical cystectomy. Scandinavian Journal Of Urology 2020, 54: 290-296. PMID: 32538224, DOI: 10.1080/21681805.2020.1777195.Peer-Reviewed Original ResearchConceptsDelayed blood transfusionEarly blood transfusionBlood transfusionRadical cystectomyBladder cancer treated with radical cystectomyPatients treated with radical cystectomyAssociated with 90-day mortalityIncreased 90-day mortalityTime of blood transfusionPrimary end pointRetrospective cohort studyMultivariate logistic regressionAssociated with mortalityDelayed transfusionMedian ageClinical deteriorationCystectomyHigher CCIOlder patientsTransfusionCohort studyEnd pointsPatient mortalityPatientsIndex admission
2019
Variation in Positive Surgical Margin Status After Radical Prostatectomy for pT2 Prostate Cancer
Tan W, Krimphove M, Cole A, Marchese M, Berg S, Lipsitz S, Löppenberg B, Nabi J, Abdollah F, Choueiri T, Kibel A, Sooriakumaran P, Trinh Q. Variation in Positive Surgical Margin Status After Radical Prostatectomy for pT2 Prostate Cancer. Clinical Genitourinary Cancer 2019, 17: e1060-e1068. PMID: 31303561, DOI: 10.1016/j.clgc.2019.06.008.Peer-Reviewed Original ResearchConceptsPositive surgical marginsFactors associated with positive surgical marginsPositive surgical margin statusPT2 prostate cancerRadical prostatectomyProstate cancerCancer-specific factorsSurgical approachMargin statusHigher hospital surgical volumeSurgical margin statusNational Cancer DatabaseHospital surgical volumeCancer-specific featuresPSM rateSurgical marginsCancer DatabaseImprove patient outcomesEvaluating patientsContribution of patientLogistic regression modelsSurgical volumeProstatectomyPatientsPatient-specificExamining the relationship between complications and perioperative mortality following radical cystectomy: a population‐based analysis
Mossanen M, Krasnow R, Zlatev D, Tan W, Preston M, Trinh Q, Kibel A, Sonpavde G, Schrag D, Chung B, Chang S. Examining the relationship between complications and perioperative mortality following radical cystectomy: a population‐based analysis. BJU International 2019, 124: 40-46. PMID: 30499636, DOI: 10.1111/bju.14636.Peer-Reviewed Original ResearchConceptsRadical cystectomyPerioperative mortalityPostoperative mortalityIncidence of perioperative complicationsTreated with RCPremier Healthcare DatabaseNature of complicationsIncreasing predicted probabilityOdds of mortalityProbability of mortalityReadmission complicationsRenal-relatedSurgical characteristicsPerioperative complicationsBladder cancerPrimary outcomeComplicationsHealthcare databasesPatientsMortalityCystectomyMultivariate regressionReadmissionHospitalisationHospital
2018
Effect of Jet Nebulization on Noninvasive Positive-Pressure Ventilation Administered with Noninvasive or Intensive Care Unit Ventilators: A Bench Study
Xu M, Dai B, Peng Y, Su J, Tan W, Zhao H. Effect of Jet Nebulization on Noninvasive Positive-Pressure Ventilation Administered with Noninvasive or Intensive Care Unit Ventilators: A Bench Study. Respiration 2018, 97: 355-362. PMID: 30544115, DOI: 10.1159/000494456.Peer-Reviewed Original ResearchConceptsNoninvasive positive pressure ventilationIntensive care unitPositive pressure ventilationIntensive care unit ventilatorsNoninvasive ventilationEffect of jet nebulizationTidal volumeJet nebulizerPressure ventilationNoninvasive positive-pressure ventilationPositive-pressure ventilationAerosol inhalation therapyActual tidal volumeInvasive ventilationInhalation therapyAerosol therapyCare unitAcute settingDeliver drugsImpact of jet nebulizationPatientsInspiratory limbVentilationTherapyExhalation valveWho Should Be Investigated for Haematuria? Results of a Contemporary Prospective Observational Study of 3556 Patients
Tan W, Feber A, Sarpong R, Khetrapal P, Rodney S, Jalil R, Mostafid H, Cresswell J, Hicks J, Rane A, Henderson A, Watson D, Cherian J, Williams N, Brew-Graves C, Kelly J, collaborators O. Who Should Be Investigated for Haematuria? Results of a Contemporary Prospective Observational Study of 3556 Patients. European Urology 2018, 74: 10-14. PMID: 29653885, DOI: 10.1016/j.eururo.2018.03.008.Peer-Reviewed Original ResearchConceptsUrinary tract cancerIncidence of urinary tract cancerInvestigation of haematuriaRisk of urinary tract cancerClinically significant cancerDiagnosis of urinary tract cancerHigh-risk cancerProspective observational studyIncidence of cancerSignificant cancerAge thresholdBladder cancerSmoking historyVisible bloodOlder patientsHaematuriaMale genderConsensus recommendationsPatientsObservational studyCancerPatient preferencesCancer diagnosisLack of consensusAge
2017
Outcomes of Intracorporeal Urinary Diversion after Robot-Assisted Radical Cystectomy: Results from the International Robotic Cystectomy Consortium
Hussein A, May P, Jing Z, Ahmed Y, Wijburg C, Canda A, Dasgupta P, Khan M, Menon M, Peabody J, Hosseini A, Kelly J, Mottrie A, Kaouk J, Hemal A, Wiklund P, Guru K, Collaborators, Wagner A, Saar M, Stockle M, Redorta J, Richstone L, Badani K, Scherr D, Khan H, Gaboardi F, Rha K, Kawa O, Tan W, Schanne F, Polakis V, Weizer A, Maatman T, Pini G, Peak T, Kibel A, Yuh B. Outcomes of Intracorporeal Urinary Diversion after Robot-Assisted Radical Cystectomy: Results from the International Robotic Cystectomy Consortium. Journal Of Urology 2017, 199: 1302-1311. PMID: 29275112, DOI: 10.1016/j.juro.2017.12.045.Peer-Reviewed Original ResearchMeSH KeywordsAgedCystectomyFemaleHumansInternational CooperationMaleMiddle AgedOperative TimeOutcome and Process Assessment, Health CarePatient ReadmissionPostoperative ComplicationsProspective StudiesRetrospective StudiesRisk FactorsRobotic Surgical ProceduresTreatment OutcomeUrinary BladderUrinary Bladder NeoplasmsUrinary DiversionConceptsRobot-assisted radical cystectomyIntracorporeal urinary diversionExtracorporeal urinary diversionShorter operative timeRadical cystectomyHigh grade complicationsUrinary diversionOperative timeGrade complicationsInternational Robotic Cystectomy Consortium databaseInternational Robotic Cystectomy ConsortiumCompare perioperative outcomesLess blood lossMultivariate logistic regression modelPostoperative predictorsBlood lossPerioperative outcomesBlood transfusionCystectomy volumeCystectomyLogistic regression modelsComplicationsConsortium databaseMulti-institutionalPatientsDevelopment of a patient and institutional‐based model for estimation of operative times for robot‐assisted radical cystectomy: results from the International Robotic Cystectomy Consortium
Hussein A, May P, Ahmed Y, Saar M, Wijburg C, Richstone L, Wagner A, Wilson T, Yuh B, Redorta J, Dasgupta P, Kawa O, Khan M, Menon M, Peabody J, Hosseini A, Gaboardi F, Pini G, Schanne F, Mottrie A, Rha K, Hemal A, Stockle M, Kelly J, Tan W, Maatman T, Poulakis V, Kaouk J, Canda A, Balbay M, Wiklund P, Guru K. Development of a patient and institutional‐based model for estimation of operative times for robot‐assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. BJU International 2017, 120: 695-701. PMID: 28620985, DOI: 10.1111/bju.13934.Peer-Reviewed Original ResearchConceptsRobot-assisted radical cystectomyLymph node dissectionSurgical timeOperative timeAssociated with surgical timeNode dissectionRadical cystectomyAssociated with operative timeAmerican Society of Anesthesiologists scoreInternational Robotic Cystectomy ConsortiumBody mass indexIleal conduit patientsNeoadjuvant chemotherapyPreoperative variablesAnesthesiologists scoreClinical stageIleal conduitOperating room schedulingSurgeon volumeConduit patientsMass indexDisease characteristicsInstitutional volumePatientsEstimations of operating time
2016
Early Oncologic Failure after Robot-Assisted Radical Cystectomy: Results from the International Robotic Cystectomy Consortium
Hussein A, Saar M, May P, Wijburg C, Richstone L, Wagner A, Wilson T, Yuh B, Redorta J, Dasgupta P, Khan M, Menon M, Peabody J, Hosseini A, Gaboardi F, Mottrie A, Rha K, Hemal A, Stockle M, Kelly J, Maatman T, Canda A, Wiklund P, Guru K, Collaborators, Balbay M, Poulakis V, Woods M, Tan W, Kawa O, Pini G, Badani K, Ahmed Y. Early Oncologic Failure after Robot-Assisted Radical Cystectomy: Results from the International Robotic Cystectomy Consortium. Journal Of Urology 2016, 197: 1427-1436. PMID: 27993668, DOI: 10.1016/j.juro.2016.12.048.Peer-Reviewed Original ResearchConceptsRobot-assisted radical cystectomyOncological failureRadical cystectomyOverall survivalDisease relapseEvaluate predictorsInternational Robotic Cystectomy ConsortiumCox proportional regression analysisPort site recurrenceKaplan-Meier methodLymph node removalOncologic surgical principlesPeritoneal carcinomatosisNodal involvementPredictors of diseaseLocal recurrenceSite recurrencePneumoperitoneum pressureCystectomyMultivariate analysisSurgical principlesPatientsMultivariate modelDiseaseRelapseEvolution of the neobladder: A critical review of open and intracorporeal neobladder reconstruction techniques
Tan W, Lamb B, Kelly J. Evolution of the neobladder: A critical review of open and intracorporeal neobladder reconstruction techniques. Scandinavian Journal Of Urology 2016, 50: 95-103. PMID: 26882458, DOI: 10.3109/21681805.2016.1141318.Peer-Reviewed Original ResearchConceptsNeobladder reconstructionRadical cystectomyRobotic cystectomyPatient selectionOrthotopic bladder reconstructionMinimally invasive cystectomyIntracorporeal neobladder reconstructionMini-laparotomyOrthotopic neobladderIleal conduitCystectomySurgical techniqueMEDLINE searchBladder reconstructionIntracorporeal approachNeobladderKeyword search criteriaIntracorporealRobotic platformPatients
2015
Complications of Radical Cystectomy and Orthotopic Reconstruction
Tan W, Lamb B, Kelly J. Complications of Radical Cystectomy and Orthotopic Reconstruction. Advances In Urology 2015, 2015: 323157. PMID: 26697063, PMCID: PMC4677163, DOI: 10.1155/2015/323157.Peer-Reviewed Original ResearchOrthotopic bladder substitutionComplications of radical cystectomyRadical cystectomyUrinary diversionIleal orthotopic bladder substitutionShorter length of hospital stayLength of hospital stayHigh-volume institutionsLow-volume institutionsEnhanced recovery pathwayOncological surveillanceEarly complicationsBladder substitutionSignificant morbidityHospital stayCystectomyFollow-upComplicationsMorbidityEnhanced recoveryMortalitySurgeryPatientsRecovery pathwaysShorter length
2014
Management of Node-Positive Bladder Cancer After Neoadjuvant Chemotherapy and Radical Cystectomy: A Survey of Current UK Practice
Tan W, Lamb B, Payne H, Hughes S, Green J, Lane T, Adshead J, Boustead G, Vasdev N. Management of Node-Positive Bladder Cancer After Neoadjuvant Chemotherapy and Radical Cystectomy: A Survey of Current UK Practice. Clinical Genitourinary Cancer 2014, 13: e153-e158. PMID: 25510376, DOI: 10.1016/j.clgc.2014.11.006.Peer-Reviewed Original ResearchConceptsNeoadjuvant chemotherapy regimenNeoadjuvant chemotherapyPositive lymph nodesRadical cystectomyAdjuvant chemotherapyTreatment of patientsBladder cancerNodal diseaseLymph nodesIndication of adjuvant chemotherapyNode-positive bladder cancerPresence of disease progressionResponse to NACCancer CenterMuscle-invasive bladder cancerCycles of gemcitabineAdvanced bladder cancerPatient performance statusUro-oncologistsChemotherapy regimenPerformance statusLack of published evidenceDisease progressionChemotherapyPatientsLoss of expression of the tumour suppressor gene AIMP3 predicts survival following radiotherapy in muscle‐invasive bladder cancer
Gurung P, Veerakumarasivam A, Williamson M, Counsell N, Douglas J, Tan W, Feber A, Crabb S, Short S, Freeman A, Powles T, Hoskin P, West C, Kelly J. Loss of expression of the tumour suppressor gene AIMP3 predicts survival following radiotherapy in muscle‐invasive bladder cancer. International Journal Of Cancer 2014, 136: 709-720. PMID: 24917520, DOI: 10.1002/ijc.29022.Peer-Reviewed Original ResearchConceptsMuscle-invasive bladder cancerMuscle-invasive bladder cancer patientsTissue-microarrayBladder cancerAssociated with survivalPredictive of survivalMethylation-specific PCRColony forming assayLoss of expressionRadical cystectomyRadiotherapy trialsRadiosensitising effectPrognostic valueMechanism of gene silencingRadiotherapyResponse to ionising radiationClinical biomarkersPatientsProtein expressionCancerMeta-analysisDNA damage responseCystectomySurvivalBladder
2012
[The comparative analysis of the common reasons of invasive ventilator alarms between medical and specialist intensive care unit].
Tan W, Sun L, Qin Z, Dai B, Zhao H, Kang J. [The comparative analysis of the common reasons of invasive ventilator alarms between medical and specialist intensive care unit]. Chinese Critical Care Medicine 2012, 24: 582-6. PMID: 23040772.Peer-Reviewed Original ResearchConceptsSpecialist intensive care unitMedical intensive care unitIntensive care unitAerosol inhalationHospital of China Medical UniversityFirst Hospital of China Medical UniversityHigh tidal volumeHigh airway pressuresHigher minute ventilationVentilator alarmsChina Medical UniversityAirway pressurePressure alarmRespiratory distressFirst HospitalCare unitTidal volumeMinute ventilationTube factorsMedical UniversityPatientsAttending physiciansSputumVentilationAirway