2024
Male Robot-Assisted Radical Cystectomy with Nerve Sparing Technique
Tan W, Ta A, Sridhar A, Kelly J. Male Robot-Assisted Radical Cystectomy with Nerve Sparing Technique. 2024, 291-302. DOI: 10.1007/978-3-031-49428-4_23.Peer-Reviewed Original Research
2023
Robot-assisted Radical Cystectomy Versus Open Radical Cystectomy: A Systematic Review and Meta-analysis of Perioperative, Oncological, and Quality of Life Outcomes Using Randomized Controlled Trials
Khetrapal P, Wong J, Tan W, Rupasinghe T, Tan W, Williams S, Boorjian S, Wijburg C, Parekh D, Wiklund P, Vasdev N, Khan M, Guru K, Catto J, Kelly J. Robot-assisted Radical Cystectomy Versus Open Radical Cystectomy: A Systematic Review and Meta-analysis of Perioperative, Oncological, and Quality of Life Outcomes Using Randomized Controlled Trials. European Urology 2023, 84: 393-405. PMID: 37169638, DOI: 10.1016/j.eururo.2023.04.004.Peer-Reviewed Original ResearchConceptsRobot-assisted radical cystectomyOpen radical cystectomyRadical cystectomyBlood lossThromboembolic eventsAssociated with better physical functionBladder cancerPositive surgical margin rateAssociated with more blood lossRisk of thromboembolic eventsHealth-related QoLQuality of life outcomesProgression-free survivalSurgical margin rateLymph node yieldRobot-assisted approachShorter operative timeShorter hospital lengthQuality of lifeRandomized controlled trialsSystematic literature searchPhysical functionWeb of ScienceNode yieldOverall survival
2022
Robotic Intracorporeal Neobladder: UCLH Experience
Weyne E, Tan W, Kelly J, Sridhar A. Robotic Intracorporeal Neobladder: UCLH Experience. 2022, 681-686. DOI: 10.1007/978-3-031-00363-9_60.Peer-Reviewed Original ResearchRobot-assisted radical cystectomyUniversity College London HospitalRadical cystectomyBladder cancerHigh-risk non-muscle-invasive bladder cancerTreatment of muscle-invasive bladder cancerNon-muscle-invasive bladder cancerMuscle-invasive bladder cancerRobotic radical cystectomyOrthotopic continent diversionPatient selectionContinent diversionCystectomyPostoperative careOperative techniqueNeobladder
2021
Recovery of health‐related quality of life in patients undergoing robot‐assisted radical cystectomy with intracorporeal diversion
Abozaid M, Tan W, Khetrapal P, Baker H, Duncan J, Sridhar A, Briggs T, Selim M, Abdallah M, Elmahdy A, Elserafy F, Kelly J. Recovery of health‐related quality of life in patients undergoing robot‐assisted radical cystectomy with intracorporeal diversion. BJU International 2021, 129: 72-79. PMID: 34092021, DOI: 10.1111/bju.15505.Peer-Reviewed Original ResearchConceptsGlobal HRQoL scoreHealth-related quality of lifeRobot-assisted radical cystectomyEORTC QLQ-C30HRQoL scoresQuality of lifeSexual functionRadical cystectomyUrinary diversionIleal conduitIC patientsRecovery of health-related quality of lifeFunction scoresClavien-Dindo complicationsHealth-related qualityPhysical function scoresRehabilitation of sexual functionIntracorporeal urinary diversionLongitudinal analysisSexual function scoresEuropean Organisation for ResearchMonths follow-upEORTC QLQ-BLM30Higher sexual function scoresReturn to baseline
2020
Morbidity and mortality after robot‐assisted radical cystectomy with intracorporeal urinary diversion in octogenarians: results from the European Association of Urology Robotic Urology Section Scientific Working Group
Mortezavi A, Crippa A, Edeling S, Pokupic S, Dell’Oglio P, Montorsi F, D'Hondt F, Mottrie A, Decaestecker K, Wijburg C, Collins J, Kelly J, Tan W, Sridhar A, John H, Canda A, Schwentner C, Rönmark E, Wiklund P, Hosseini A. Morbidity and mortality after robot‐assisted radical cystectomy with intracorporeal urinary diversion in octogenarians: results from the European Association of Urology Robotic Urology Section Scientific Working Group. BJU International 2020, 127: 585-595. PMID: 33058469, PMCID: PMC8246851, DOI: 10.1111/bju.15274.Peer-Reviewed Original ResearchConceptsPatients aged <Intracorporeal urinary diversionCancer-specific mortalityOther-cause mortalityPostoperative complicationsRadical cystectomyMortality rateUrinary diversionBladder cancerOutcomes of patients aged <Predictor of high-grade complicationsHigh-grade complication rateOther-cause mortality ratesRobot-assisted radical cystectomyMultivariate logistic regression analysisClavien-Dindo gradeLaparoscopic radical cystectomyHigh-grade complicationsPostoperative mortality rateMinimally invasive approachTreatment-related risksLogistic regression analysisOCM ratesPostoperative variablesComplication rateQuality of surgical care can impact survival in patients with bladder cancer after robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium
Ahmed Y, Hussein A, May P, Ahmad B, Khan A, Benkowski J, Durrani A, Khan S, Kozlowski J, Saar M, Wijburg C, Richstone L, Wagner A, Yuh B, Redorta J, Dasgupta P, Khan M, Menon M, Peabody J, Hosseini A, Gaboardi F, Pini G, Schanne F, Mottrie A, Rha K, Hemal A, Stockle M, Kelly J, Tan W, Maatman T, Poulakis V, Kaouk J, Canda A, Balbay M, Wiklund P, Guru K. Quality of surgical care can impact survival in patients with bladder cancer after robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. African Journal Of Urology 2020, 26: 22. DOI: 10.1186/s12301-020-00031-y.Peer-Reviewed Original ResearchOrgan-confined diseaseLocally advanced diseaseDisease-specific survivalRecurrence-free survivalRobot-assisted radical cystectomyOverall survivalQuality of surgical careRadical cystectomyBladder cancerSurgical carePositive lymph node statusMultivariate stepwise logistic regressionImpact of surgical factorsPositive surgical marginsLymph node statusKaplan-Meier methodPredictors of survivalStepwise logistic regressionCompare surgical performanceOS ratesSurgical marginsPT stageAdjuvant chemotherapyNode statusAdvanced disease
2019
PE61 Survival outcome after robotic assisted radical cystectomy with intracorporal urinary diversion in elderly patients
Mortezavi A, Edeling S, Pokupic S, Dell’oglio P, Montorsi F, D'hondt F, Mottrie A, Decaestecker K, Wijburg C, Kelly J, Tan W, Sridhar A, John H, Canda E, Schwentener C, Rönmark E, Wiklund P, Hosseini A. PE61 Survival outcome after robotic assisted radical cystectomy with intracorporal urinary diversion in elderly patients. European Urology Open Science 2019, 18: e2636. DOI: 10.1016/s1569-9056(19)32747-2.Peer-Reviewed Original ResearchRobot-assisted radical cystectomyIntracorporeal urinary diversionRadical cystectomySurvival outcomesUrinary diversionElderly patientsOpen Versus Robotic Cystectomy: A Propensity Score Matched Analysis Comparing Survival Outcomes
Moschini M, Zamboni S, Soria F, Mathieu R, Xylinas E, Tan W, Kelly J, Simone G, Meraney A, Krishna S, Konety B, Mattei A, Baumeister P, Mordasini L, Montorsi F, Briganti A, Gallina A, Stabile A, Sanchez-Salas R, Cathelineau X, Rink M, Necchi A, Karakiewicz P, Rouprêt M, Koupparis A, Kassouf W, Scherr D, Ploussard G, Boorjian S, Lotan Y, Sooriakumaran P, Shariat S. Open Versus Robotic Cystectomy: A Propensity Score Matched Analysis Comparing Survival Outcomes. Journal Of Clinical Medicine 2019, 8: 1192. PMID: 31395826, PMCID: PMC6722857, DOI: 10.3390/jcm8081192.Peer-Reviewed Original ResearchRobot-assisted radical cystectomyOpen radical cystectomyCancer-specific mortalitySurvival outcomesRadical cystectomyPropensity score matchingBladder cancerPatients treated with robot-assisted radical cystectomyAssociation of surgical techniqueLong-term survival outcomesCancer-specific mortality ratesMultivariate Cox regression analysisMultivariate competing risk analysisOpen radical cystectomy patientsRobot-assisted radical cystectomy patientsBilateral pelvic lymphadenectomyCompare survival outcomesMedian follow-upUrothelial bladder cancerScore matchingCox regression analysisPropensity-matched cohortCompeting risk analysisPelvic lymphadenectomyMulticentre cohortDifferences in trends in the use of robot‐assisted and open radical cystectomy and changes over time in peri‐operative outcomes among selected centres in North America and Europe: an international multicentre collaboration
Zamboni S, Soria F, Mathieu R, Xylinas E, Abufaraj M, D`Andrea D, Tan W, Kelly J, Simone G, Gallucci M, Meraney A, Krishna S, Konety B, Antonelli A, Simeone C, Baumeister P, Mattei A, Briganti A, Gallina A, Montorsi F, Rink M, Aziz A, Karakiewicz P, Rouprêt M, Koupparis A, Scherr D, Ploussard G, Sooriakumaran P, Shariat S, Moschini M, Urologists U. Differences in trends in the use of robot‐assisted and open radical cystectomy and changes over time in peri‐operative outcomes among selected centres in North America and Europe: an international multicentre collaboration. BJU International 2019, 124: 656-664. PMID: 31055865, DOI: 10.1111/bju.14791.Peer-Reviewed Original ResearchRobot-assisted radical cystectomyOpen radical cystectomyPeri-operative outcomesRadical cystectomyNorth American centresContemporary patientsPatients treated with open radical cystectomyEuropean centresPatients treated with robot-assisted radical cystectomyLower American Society of Anesthesiologists scoresAmerican Society of Anesthesiologists scoreLower blood lossRe-operation rateAmerican centresInternational multicentre collaborationContemporary seriesT stageBlood lossEarly complicationsRe-operationAnesthesiologists scoreBladder cancerGroup patientsRetrospective evaluationCystectomy
2018
Is experience with extracorporeal urinary diversion following robotic assisted radical cystectomy necessary before transitioning to intracorporeal urinary diversion?
Tan W, Kelly J. Is experience with extracorporeal urinary diversion following robotic assisted radical cystectomy necessary before transitioning to intracorporeal urinary diversion? Translational Andrology And Urology 2018, 0: s735-s737. PMID: 30687611, PMCID: PMC6323277, DOI: 10.21037/tau.2018.08.22.Peer-Reviewed Original Research
2017
Outcomes of Intracorporeal Urinary Diversion after Robot-Assisted Radical Cystectomy: Results from the International Robotic Cystectomy Consortium
Hussein A, May P, Jing Z, Ahmed Y, Wijburg C, Canda A, Dasgupta P, Khan M, Menon M, Peabody J, Hosseini A, Kelly J, Mottrie A, Kaouk J, Hemal A, Wiklund P, Guru K, Collaborators, Wagner A, Saar M, Stockle M, Redorta J, Richstone L, Badani K, Scherr D, Khan H, Gaboardi F, Rha K, Kawa O, Tan W, Schanne F, Polakis V, Weizer A, Maatman T, Pini G, Peak T, Kibel A, Yuh B. Outcomes of Intracorporeal Urinary Diversion after Robot-Assisted Radical Cystectomy: Results from the International Robotic Cystectomy Consortium. Journal Of Urology 2017, 199: 1302-1311. PMID: 29275112, DOI: 10.1016/j.juro.2017.12.045.Peer-Reviewed Original ResearchMeSH KeywordsAgedCystectomyFemaleHumansInternational CooperationMaleMiddle AgedOperative TimeOutcome and Process Assessment, Health CarePatient ReadmissionPostoperative ComplicationsProspective StudiesRetrospective StudiesRisk FactorsRobotic Surgical ProceduresTreatment OutcomeUrinary BladderUrinary Bladder NeoplasmsUrinary DiversionConceptsRobot-assisted radical cystectomyIntracorporeal urinary diversionExtracorporeal urinary diversionShorter operative timeRadical cystectomyHigh grade complicationsUrinary diversionOperative timeGrade complicationsInternational Robotic Cystectomy Consortium databaseInternational Robotic Cystectomy ConsortiumCompare perioperative outcomesLess blood lossMultivariate logistic regression modelPostoperative predictorsBlood lossPerioperative outcomesBlood transfusionCystectomy volumeCystectomyLogistic regression modelsComplicationsConsortium databaseMulti-institutionalPatientsIntracorporeal robot‐assisted radical cystectomy, together with an enhanced recovery programme, improves postoperative outcomes by aggregating marginal gains
Tan W, Tan M, Lamb B, Sridhar A, Mohammed A, Baker H, Nathan S, Briggs T, Tan M, Kelly J. Intracorporeal robot‐assisted radical cystectomy, together with an enhanced recovery programme, improves postoperative outcomes by aggregating marginal gains. BJU International 2017, 121: 632-639. PMID: 29124853, DOI: 10.1111/bju.14073.Peer-Reviewed Original ResearchConceptsLength of hospital stayOpen radical cystectomyRobot-assisted radical cystectomyPeri-operative outcomesRadical cystectomyERAS programmeERAS groupERAS pathwayReadmission ratesOpen radical cystectomy groupAmerican Society of Anesthesiologists scoreIntracorporeal robot-assisted radical cystectomyPeri-operative anaemiaLymph node yieldRadical cystectomy casesClavien-Dindo systemScore-matched cohort of patientsCohort of patientsLevel 1 evidenceImproving postoperative outcomesIntracorporeal urinary diversionBody mass indexScore-matched cohortGastrointestinal-related complicationsPrimary outcome measureDevelopment of a patient and institutional‐based model for estimation of operative times for robot‐assisted radical cystectomy: results from the International Robotic Cystectomy Consortium
Hussein A, May P, Ahmed Y, Saar M, Wijburg C, Richstone L, Wagner A, Wilson T, Yuh B, Redorta J, Dasgupta P, Kawa O, Khan M, Menon M, Peabody J, Hosseini A, Gaboardi F, Pini G, Schanne F, Mottrie A, Rha K, Hemal A, Stockle M, Kelly J, Tan W, Maatman T, Poulakis V, Kaouk J, Canda A, Balbay M, Wiklund P, Guru K. Development of a patient and institutional‐based model for estimation of operative times for robot‐assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. BJU International 2017, 120: 695-701. PMID: 28620985, DOI: 10.1111/bju.13934.Peer-Reviewed Original ResearchConceptsRobot-assisted radical cystectomyLymph node dissectionSurgical timeOperative timeAssociated with surgical timeNode dissectionRadical cystectomyAssociated with operative timeAmerican Society of Anesthesiologists scoreInternational Robotic Cystectomy ConsortiumBody mass indexIleal conduit patientsNeoadjuvant chemotherapyPreoperative variablesAnesthesiologists scoreClinical stageIleal conduitOperating room schedulingSurgeon volumeConduit patientsMass indexDisease characteristicsInstitutional volumePatientsEstimations of operating timeThe Role of Robotics in the Invasive Management of Bladder Cancer
Khetrapal P, Tan W, Lamb B, Tan M, Baker H, Thompson J, Sridhar A, Kelly J, Briggs T. The Role of Robotics in the Invasive Management of Bladder Cancer. Current Urology Reports 2017, 18: 57. PMID: 28634646, DOI: 10.1007/s11934-017-0706-7.Peer-Reviewed Original ResearchConceptsRobot-assisted radical cystectomyRobot-assisted laparoscopic prostatectomyRadical cystectomyUrinary reconstructionIntracorporeal robot-assisted radical cystectomyManagement of bladder cancerOpen radical cystectomySurgical learning curveBladder cancer surgeryEnhanced recovery programmeComparison of outcomesLaparoscopic prostatectomyOncological outcomesIleus ratesBladder cancerCancer surgeryPerioperative measuresOpen techniqueInvasive managementShort recovery periodRobotic approachImprove outcomesPatient outcomesReduce recovery timeCystectomyMP92-05 CALCULATING SURGICAL TIME FOR ROBOT-ASSISTED RADICAL CYSTECTOMY BASED ON PATIENT RELATED METRICS & INSTITUTIONAL EXPERIENCE: RESULTS FROM THE INTERNATIONAL ROBOTIC CYSTECTOMY CONSORTIUM
May P, Dexter F, Hussein A, Ahmed Y, Hosseini A, Wiklund P, Peabody J, Ho-Rha K, Richstone L, Khan S, Wijburg C, Saar M, Canda A, Kaouk J, Wagner A, Yuh B, Redorta J, Balbay M, Maatman T, Smits G, Menon M, Stoeckle M, Kawa O, Hemal A, Pini G, Gaboardi F, Mottrie A, Kelly J, Tan W, Schanne F, Weizer A, Peak T, Guru K. MP92-05 CALCULATING SURGICAL TIME FOR ROBOT-ASSISTED RADICAL CYSTECTOMY BASED ON PATIENT RELATED METRICS & INSTITUTIONAL EXPERIENCE: RESULTS FROM THE INTERNATIONAL ROBOTIC CYSTECTOMY CONSORTIUM. Journal Of Urology 2017, 197: e1227-e1228. DOI: 10.1016/j.juro.2017.02.2866.Peer-Reviewed Original ResearchInternational Robotic Cystectomy ConsortiumRobot-assisted radical cystectomy588 Enhanced recovery enhances reduction of length of stay in patients treated with robotic assisted radical cystectomy with intracorporeal urinary diversion
Tan W, Lamb B, Tan M, Sridhar A, Mohammed A, Baker H, Briggs T, Tan M, Kelly J. 588 Enhanced recovery enhances reduction of length of stay in patients treated with robotic assisted radical cystectomy with intracorporeal urinary diversion. European Urology Open Science 2017, 16: e1022. DOI: 10.1016/s1569-9056(17)30645-0.Peer-Reviewed Original ResearchBlood Transfusion Requirement and Not Preoperative Anemia Are Associated with Perioperative Complications Following Intracorporeal Robot-Assisted Radical Cystectomy
Tan W, Lamb B, Khetrapal P, Tan M, Tan M, Sridhar A, Cervi E, Rodney S, Busuttil G, Nathan S, Hines J, Shaw G, Mohammed A, Baker H, Briggs T, Klein A, Richards T, Kelly J. Blood Transfusion Requirement and Not Preoperative Anemia Are Associated with Perioperative Complications Following Intracorporeal Robot-Assisted Radical Cystectomy. Journal Of Endourology 2017, 31: 141-148. PMID: 27901350, DOI: 10.1089/end.2016.0730.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnemiaBlood Loss, SurgicalBlood TransfusionCystectomyFemaleHumansMaleMiddle AgedNeoadjuvant TherapyPerioperative PeriodPostoperative ComplicationsPreoperative PeriodPrevalenceProspective StudiesRobotic Surgical ProceduresTransfusion ReactionUrinary Bladder NeoplasmsUrinary DiversionConceptsBlood transfusion requirementsAssociated with perioperative morbidityPreoperative anemiaTransfusion requirementsBlood transfusionComplication ratePerioperative morbidityAssociated with increased surgical riskPresence of preoperative anemiaPrevalence of preoperative anemiaAssociated with increased perioperative morbidityAssociated with perioperative complicationsImpact of preoperative anemiaAssociated with increased complicationsPostoperative blood transfusion rateLower lymph node yieldPostoperative blood transfusion requirementsRobot-assisted radical cystectomyPreoperatively anemic patientsIntraoperative blood transfusionLymph node yieldPostoperative blood transfusionBlood transfusion rateClavien-Dindo systemHospital length of stay
2016
Early Oncologic Failure after Robot-Assisted Radical Cystectomy: Results from the International Robotic Cystectomy Consortium
Hussein A, Saar M, May P, Wijburg C, Richstone L, Wagner A, Wilson T, Yuh B, Redorta J, Dasgupta P, Khan M, Menon M, Peabody J, Hosseini A, Gaboardi F, Mottrie A, Rha K, Hemal A, Stockle M, Kelly J, Maatman T, Canda A, Wiklund P, Guru K, Collaborators, Balbay M, Poulakis V, Woods M, Tan W, Kawa O, Pini G, Badani K, Ahmed Y. Early Oncologic Failure after Robot-Assisted Radical Cystectomy: Results from the International Robotic Cystectomy Consortium. Journal Of Urology 2016, 197: 1427-1436. PMID: 27993668, DOI: 10.1016/j.juro.2016.12.048.Peer-Reviewed Original ResearchConceptsRobot-assisted radical cystectomyOncological failureRadical cystectomyOverall survivalDisease relapseEvaluate predictorsInternational Robotic Cystectomy ConsortiumCox proportional regression analysisPort site recurrenceKaplan-Meier methodLymph node removalOncologic surgical principlesPeritoneal carcinomatosisNodal involvementPredictors of diseaseLocal recurrenceSite recurrencePneumoperitoneum pressureCystectomyMultivariate analysisSurgical principlesPatientsMultivariate modelDiseaseRelapseRobotic Assisted Radical Cystectomy with Extracorporeal Urinary Diversion Does Not Show a Benefit over Open Radical Cystectomy: A Systematic Review and Meta-Analysis of Randomised Controlled Trials
Tan W, Khetrapal P, Tan W, Rodney S, Chau M, Kelly J. Robotic Assisted Radical Cystectomy with Extracorporeal Urinary Diversion Does Not Show a Benefit over Open Radical Cystectomy: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. PLOS ONE 2016, 11: e0166221. PMID: 27820855, PMCID: PMC5098822, DOI: 10.1371/journal.pone.0166221.Peer-Reviewed Original ResearchConceptsRobot-assisted radical cystectomyOpen radical cystectomyMeta-analysis of randomised controlled trialsExtracorporeal urinary diversionRandomised controlled trialsRadical cystectomyUrinary diversionPerioperative morbidityBladder cancerLack of Level I evidenceRobot-assisted radical cystectomy groupsPositive lymph node statusOutcomes of robot-assisted radical cystectomySystematic reviewControlled trialsOpen radical cystectomy patientsEfficacy of robot-assisted radical cystectomyInclusion criteriaPositive surgical marginsLymph node statusLymph node yieldMeta-analysisLevel I evidenceIntracorporeal urinary diversionWell-designed trialsPort-Site Metastases After Robotic Radical Cystectomy: A Systematic Review and Management Options
Khetrapal P, Tan W, Lamb B, Nathan S, Briggs T, Shankar A, Ramachandran N, Freeman A, Mitra A, Kelly J. Port-Site Metastases After Robotic Radical Cystectomy: A Systematic Review and Management Options. Clinical Genitourinary Cancer 2016, 15: 440-444. PMID: 28209455, DOI: 10.1016/j.clgc.2016.06.012.Peer-Reviewed Original ResearchConceptsRobot-assisted radical cystectomyPort-site metastasisRadical cystectomyCase of port-site metastasisLymph node-positive diseaseMuscle-invasive bladder cancerIntracorporeal robot-assisted radical cystectomySystematic reviewNode-positive diseaseSystematic review of MEDLINERobotic radical cystectomyIdentified 4 casesTreatment of chemotherapyReview of MEDLINEDisease-free statusSalvage chemotherapyPrimary tumorSurgical excisionMultimodal treatmentPublished studiesAggressive treatmentBladder cancerTreatment optionsEmbase databasesPatient factors