2023
Symptomatic benefits of testosterone treatment in patient subgroups: a systematic review, individual participant data meta-analysis, and aggregate data meta-analysis
Hudson J, Cruickshank M, Quinton R, Aucott L, Wu F, Grossmann M, Bhasin S, Snyder P, Ellenberg S, Travison T, Brock G, Gianatti E, van der Schouw Y, Emmelot-Vonk M, Giltay E, Hackett G, Ramachandran S, Svartberg J, Hildreth K, Antonic K, Tenover J, Tan H, Ho Chee Kong C, Tan W, Marks L, Ross R, Schwartz R, Manson P, Roberts S, Skovsager Andersen M, Velling Magnussen L, Aceves-Martins M, Gillies K, Hernández R, Oliver N, Dhillo W, Bhattacharya S, Brazzelli M, Jayasena C. Symptomatic benefits of testosterone treatment in patient subgroups: a systematic review, individual participant data meta-analysis, and aggregate data meta-analysis. The Lancet Healthy Longevity 2023, 4: e561-e572. PMID: 37804846, DOI: 10.1016/s2666-7568(23)00169-1.Peer-Reviewed Original ResearchConceptsBenefits of testosterone treatmentData meta-analysisParticipant data meta-analysisSerum total testosteroneBaseline serum total testosteroneMild erectile dysfunctionTestosterone treatmentParticipant dataMeta-analysisPatient ageIIEF-15Sexual functionTotal testosteroneErectile dysfunctionSymptomatic benefitLow testosteroneSerum total testosterone concentrationsAging Male Symptoms ScoreSystematic reviewBaseline serum testosteroneHealth Technology Assessment programmeOlder menIIEF-15 scoreTestosterone replacement therapyMinimal clinically important difference
2021
Recovery of health‐related quality of life in patients undergoing robot‐assisted radical cystectomy with intracorporeal diversion
Abozaid M, Tan W, Khetrapal P, Baker H, Duncan J, Sridhar A, Briggs T, Selim M, Abdallah M, Elmahdy A, Elserafy F, Kelly J. Recovery of health‐related quality of life in patients undergoing robot‐assisted radical cystectomy with intracorporeal diversion. BJU International 2021, 129: 72-79. PMID: 34092021, DOI: 10.1111/bju.15505.Peer-Reviewed Original ResearchConceptsGlobal HRQoL scoreHealth-related quality of lifeRobot-assisted radical cystectomyEORTC QLQ-C30HRQoL scoresQuality of lifeSexual functionRadical cystectomyUrinary diversionIleal conduitIC patientsRecovery of health-related quality of lifeFunction scoresClavien-Dindo complicationsHealth-related qualityPhysical function scoresRehabilitation of sexual functionIntracorporeal urinary diversionLongitudinal analysisSexual function scoresEuropean Organisation for ResearchMonths follow-upEORTC QLQ-BLM30Higher sexual function scoresReturn to baseline