2024
Comparison between high-flow nasal cannula and conventional oxygen therapy in COVID-19 patients: a systematic review and meta-analysis
Wang J, Peng Y, Dai B, Hou H, Zhao H, Wang W, Tan W. Comparison between high-flow nasal cannula and conventional oxygen therapy in COVID-19 patients: a systematic review and meta-analysis. Therapeutic Advances In Respiratory Disease 2024, 18: 17534666231225323. PMID: 38230522, PMCID: PMC10798115, DOI: 10.1177/17534666231225323.Peer-Reviewed Original ResearchConceptsAcute hypoxemic respiratory failureHigh-flow nasal cannulaConventional oxygen therapyCOVID-19-related acute hypoxemic respiratory failureIntensive care unitHospital length of stayInvasive mechanical ventilationLength of stayIntensive care unit settingCOVID-19 patientsIntubation rateNasal cannulaMechanical ventilationOxygen therapyRatio of arterial oxygen partial pressure to fractional inspired oxygenHospital lengthArterial oxygen partial pressure to fractional inspired oxygenEfficacy of high-flow nasal cannulaIntensive care unit length of stayControlled trialsSystematic reviewRespiratory support strategiesIntensive care unit lengthHypoxemic respiratory failureMortality rate
2023
Symptomatic benefits of testosterone treatment in patient subgroups: a systematic review, individual participant data meta-analysis, and aggregate data meta-analysis
Hudson J, Cruickshank M, Quinton R, Aucott L, Wu F, Grossmann M, Bhasin S, Snyder P, Ellenberg S, Travison T, Brock G, Gianatti E, van der Schouw Y, Emmelot-Vonk M, Giltay E, Hackett G, Ramachandran S, Svartberg J, Hildreth K, Antonic K, Tenover J, Tan H, Ho Chee Kong C, Tan W, Marks L, Ross R, Schwartz R, Manson P, Roberts S, Skovsager Andersen M, Velling Magnussen L, Aceves-Martins M, Gillies K, Hernández R, Oliver N, Dhillo W, Bhattacharya S, Brazzelli M, Jayasena C. Symptomatic benefits of testosterone treatment in patient subgroups: a systematic review, individual participant data meta-analysis, and aggregate data meta-analysis. The Lancet Healthy Longevity 2023, 4: e561-e572. PMID: 37804846, DOI: 10.1016/s2666-7568(23)00169-1.Peer-Reviewed Original ResearchConceptsBenefits of testosterone treatmentData meta-analysisParticipant data meta-analysisSerum total testosteroneBaseline serum total testosteroneMild erectile dysfunctionTestosterone treatmentParticipant dataMeta-analysisPatient ageIIEF-15Sexual functionTotal testosteroneErectile dysfunctionSymptomatic benefitLow testosteroneSerum total testosterone concentrationsAging Male Symptoms ScoreSystematic reviewBaseline serum testosteroneHealth Technology Assessment programmeOlder menIIEF-15 scoreTestosterone replacement therapyMinimal clinically important differenceThe effects of flow settings during high-flow nasal cannula support for adult subjects: a systematic review
Li J, Albuainain F, Tan W, Scott J, Roca O, Mauri T. The effects of flow settings during high-flow nasal cannula support for adult subjects: a systematic review. Critical Care 2023, 27: 78. PMID: 36855198, PMCID: PMC9974062, DOI: 10.1186/s13054-023-04361-5.Peer-Reviewed Original ResearchConceptsHigh-flow nasal cannulaHigh-flow nasal cannula treatmentIn vivo studiesPatient's peak inspiratory flowHigh-flow nasal cannula supportFraction of inspired oxygenPositive end-expiratory pressurePeak inspiratory flowSystematic reviewEnd-expiratory pressureDead space washoutNon-dependent lung regionsIn vitro studiesRisk of biasROX indexNasal cannulaClinical findingsImprove oxygenationPediatric populationPatient discomfortAlveolar overdistentionInspiratory flowWeb of SciencePatient comfortPatients
2022
A systematic review and meta-analysis on delaying surgery for urothelial carcinoma of bladder and upper tract urothelial carcinoma: Implications for the COVID19 pandemic and beyond
Leow J, Tan W, Tan W, Tan T, Chan V, Tikkinen K, Kamat A, Sengupta S, Meng M, Shariat S, Roupret M, Decaestecker K, Vasdev N, Chong Y, Enikeev D, Giannarini G, Ficarra V, Teoh J, Collaborators O. A systematic review and meta-analysis on delaying surgery for urothelial carcinoma of bladder and upper tract urothelial carcinoma: Implications for the COVID19 pandemic and beyond. Frontiers In Surgery 2022, 9: 879774. PMID: 36268209, PMCID: PMC9577485, DOI: 10.3389/fsurg.2022.879774.Peer-Reviewed Original ResearchRadical nephro-ureterectomyAssociated with poor overall survivalRadical cystectomyNeoadjuvant chemotherapyPoor overall survivalOverall survivalUrothelial carcinomaSurvival outcomesUrothelial carcinoma of bladderAssociated with poor survival outcomesUpper tract urothelial carcinomaAssociated with overall survivalDiagnosis of UCBCancer-specific survivalInvasive urothelial carcinomaCarcinoma of bladderUrologic cancer surgeryMeta-analysisPoor survival outcomesSystematic reviewDefinitive surgeryBetween-study heterogeneityDelayed surgeryNephro-ureterectomyUpper tractAdverse cardiovascular events and mortality in men during testosterone treatment: an individual patient and aggregate data meta-analysis
Hudson J, Cruickshank M, Quinton R, Aucott L, Aceves-Martins M, Gillies K, Bhasin S, Snyder P, Ellenberg S, Grossmann M, Travison T, Gianatti E, van der Schouw Y, Emmelot-Vonk M, Giltay E, Hackett G, Ramachandran S, Svartberg J, Hildreth K, Antonic K, Brock G, Tenover J, Tan H, Kong C, Tan W, Marks L, Ross R, Schwartz R, Manson P, Roberts S, Andersen M, Magnussen L, Hernández R, Oliver N, Wu F, Dhillo W, Bhattacharya S, Brazzelli M, Jayasena C. Adverse cardiovascular events and mortality in men during testosterone treatment: an individual patient and aggregate data meta-analysis. The Lancet Healthy Longevity 2022, 3: e381-e393. PMID: 35711614, PMCID: PMC9184259, DOI: 10.1016/s2666-7568(22)00096-4.Peer-Reviewed Original ResearchConceptsRisk of biasMeta-analysisStudy designSystematic reviewInclusion criteriaCochrane Database of Systematic ReviewsCochrane risk of bias toolDatabase of Systematic ReviewsRisk of bias toolMEDLINE In-Process & Other Non-Indexed CitationsIn-Process & Other Non-Indexed CitationsTwo-stage meta-analysisCharacteristics of interventionsOther Non-Indexed CitationsMeta-analysis of randomised controlled trialsOne-stage meta-analysisFull-text screeningRandomised controlled trialsNon-Indexed CitationsCardiovascular eventsAggregate data meta-analysisCoronary heart diseaseData meta-analysisPeer-reviewed publicationsCochrane Controlled Trials RegisterComparison between high-flow nasal cannula and noninvasive ventilation in COVID-19 patients: a systematic review and meta-analysis
Peng Y, Dai B, Zhao H, Wang W, Kang J, Hou H, Tan W. Comparison between high-flow nasal cannula and noninvasive ventilation in COVID-19 patients: a systematic review and meta-analysis. Therapeutic Advances In Respiratory Disease 2022, 16: 17534666221113663. PMID: 35861299, PMCID: PMC9340323, DOI: 10.1177/17534666221113663.Peer-Reviewed Original ResearchConceptsHigh-flow nasal cannulaAcute hypoxemic respiratory failureHigh-flow nasal cannula groupIntensive care unitClinical outcomes of COVID-19Noninvasive ventilation groupNoninvasive ventilationInvasive mechanical ventilationRandomized controlled trialsOutcomes of COVID-19Intubation rateNasal cannulaClinical outcomesCOVID-19-related acute hypoxemic respiratory failureMechanical ventilationHospital LOSPositive airway pressureHypoxemic respiratory failureMortality rateIntensive care unit LOSMeta-analysisSystematic reviewCPAP groupCOVID-19 patientsAirway pressure
2021
Intravesical Chemohyperthermia vs. Bacillus Calmette-Guerin Instillation for Intermediate- and High-Risk Non-muscle Invasive Bladder Cancer: A Systematic Review and Meta-Analysis
Zhao H, Chan V, Castellani D, Chan E, Ong W, Peng Q, Moschini M, Krajewski W, Pradere B, Ng C, Enikeev D, Vasdev N, Ekin G, Sousa A, Leon J, Guerrero-Ramos F, Tan W, Kelly J, Shariat S, Witjes J, Teoh J. Intravesical Chemohyperthermia vs. Bacillus Calmette-Guerin Instillation for Intermediate- and High-Risk Non-muscle Invasive Bladder Cancer: A Systematic Review and Meta-Analysis. Frontiers In Surgery 2021, 8: 775527. PMID: 34888347, PMCID: PMC8649716, DOI: 10.3389/fsurg.2021.775527.Peer-Reviewed Original ResearchNon-muscle invasive bladder cancerHigh-risk non-muscle invasive bladder cancerInvasive bladder cancerOncological outcomesSafety profileBladder cancerAdverse eventsMeta-analysisBacillus Calmette-Guerin instillationsHigh-risk NMIBC patientsIntravesical bacillus Calmette-GuerinMeta-analysis of clinical studiesBCG maintenance therapySystematic reviewMonths recurrence rateCochrane RoB toolCertainty of evidenceRisk of biasComprehensive literature searchBCG shortageChemotherapy maintenanceNMIBC patientsBCG treatmentMaintenance therapyRecurrence rate1459 Intravesical Chemohyperthermia Versus Bacillus Calmette-Guerin Instillation for Intermediate- And High-Risk Non-Muscle Invasive Bladder Cancer: A Systematic Review and Meta-Analysis
Zhao H, Chan V, Castellani D, Chan E, Ong W, Peng Q, Moschini M, Krajewski W, Pradere B, Ng C, Enikeev D, Vasdev N, Ekin G, Sousa A, Leon J, Guerrero-Ramos F, Tan W, Kelly J, Shariat S, Witjes J, Teoh J. 1459 Intravesical Chemohyperthermia Versus Bacillus Calmette-Guerin Instillation for Intermediate- And High-Risk Non-Muscle Invasive Bladder Cancer: A Systematic Review and Meta-Analysis. British Journal Of Surgery 2021, 108: znab259.955. DOI: 10.1093/bjs/znab259.955.Peer-Reviewed Original ResearchNon-muscle invasive bladder cancerHigh-risk non-muscle invasive bladder cancerRecurrence-free survivalProgression-free survivalInvasive bladder cancerCarcinoma in situChemo-hyperthermiaAdverse eventsChemotherapy instillationSafety profileBladder cancerBCG groupBCG maintenance therapyTrans-urethral resectionMeta-analysisMonths recurrence rateSystematic reviewComprehensive literature searchQuality of evidenceBCG failureBCG shortageMaintenance therapyOncological outcomesRandomised controlled trialsRecurrence rateP0773 Intravesical chemohyperthermia versus bacillus calmette-guerin instillation for intermediate- and high-risk non-muscle invasive bladder cancer: A systematic review and meta-analysis
Zhao H, Chan V, Castellani D, Chan E, Ong W, Peng Q, Moschini M, Krajewski W, Pradere B, Ng C, Enikeev D, Vasdev N, Ekin G, Sousa A, Leon J, Guerrero-Ramos F, Tan W, Kelly J, Shariat S, Witjes J, Teoh J. P0773 Intravesical chemohyperthermia versus bacillus calmette-guerin instillation for intermediate- and high-risk non-muscle invasive bladder cancer: A systematic review and meta-analysis. European Urology 2021, 79: s1068-s1069. DOI: 10.1016/s0302-2838(21)01148-9.Peer-Reviewed Original ResearchDelayed surgery for localised and metastatic renal cell carcinoma: a systematic review and meta-analysis for the COVID-19 pandemic
Chan V, Tan W, Leow J, Tan W, Ong W, Chiu P, Gurung P, Pirola G, Orecchia L, Liew M, Lee H, Wang Y, Chen I, Castellani D, Wroclawski M, Mayor N, Sathianathen N, Braga I, Liu Z, Moon D, Tikkinen K, Kamat A, Meng M, Ficarra V, Giannarini G, Teoh J. Delayed surgery for localised and metastatic renal cell carcinoma: a systematic review and meta-analysis for the COVID-19 pandemic. World Journal Of Urology 2021, 39: 4295-4303. PMID: 34031748, PMCID: PMC8143063, DOI: 10.1007/s00345-021-03734-1.Peer-Reviewed Original ResearchConceptsMetastatic renal cell carcinomaRenal cell carcinomaLocalised RCCDelayed surgeryCytoreductive nephrectomyDeferred CNOverall survivalCell carcinomaTargeted therapyAssociated with worse cancer-specific survivalAssociated with better overall survivalT1a renal cell carcinomaEffect of delaying surgeryDeferred cytoreductive nephrectomyCancer-specific survivalMeta-analysisElective cancer surgeryNewcastle-Ottawa ScaleSystematic reviewComprehensive literature searchUpfront CNOncological effectivenessRisk of biasImmediate surgeryRandomised controlled trials
2019
Non-visible haematuria for the Detection of Bladder, Upper Tract, and Kidney Cancer: An Updated Systematic Review and Meta-analysis
Jubber I, Shariat S, Conroy S, Tan W, Gordon P, Lotan Y, Messing E, Stenzl A, Rhijn B, Kelly J, Catto J, Cumberbatch M. Non-visible haematuria for the Detection of Bladder, Upper Tract, and Kidney Cancer: An Updated Systematic Review and Meta-analysis. European Urology 2019, 77: 583-598. PMID: 31791622, DOI: 10.1016/j.eururo.2019.10.010.Peer-Reviewed Original ResearchConceptsNon-visible haematuriaUpper tract urothelial carcinomaMeta-analysisSystematic reviewKidney cancerSystematic review of original articlesUrological cancersRisk of cancerIncidence of cancerReview of original articlesCancer detection rateRe-evaluation of patientsPublic health implicationsBladder cancerNarrative synthesisDiagnosis of BCInclusion criteriaMeta-analysesCigarette smokingHealth implicationsDiagnosis of bladder cancerMale sexEstimated riskHigh-risk patientsGroup of individualsPD-L1/PD-1 Biomarker for Metastatic Urothelial Cancer that Progress Post-platinum Therapy: A Systematic Review and Meta-analysis
Tan W, Tan W, Inman B. PD-L1/PD-1 Biomarker for Metastatic Urothelial Cancer that Progress Post-platinum Therapy: A Systematic Review and Meta-analysis. Bladder Cancer 2019, 5: 211-223. PMID: 31867425, PMCID: PMC6919639, DOI: 10.3233/blc-190238.Peer-Reviewed Original ResearchImmune checkpoint inhibitorsProgression-free survivalMetastatic urothelial carcinomaImmune checkpoint inhibitor therapyProgrammed death-ligand 1Response ratePooled Kaplan-Meier analysisBiomarker statusHigher overall response rateAnalyzed response ratesMetastatic urothelial cancerDeath-ligand 1Programmed death-1Platinum-based chemotherapyPD-L1/PD-1Kaplan-Meier analysisMeta-analysisOverall response rateProportional hazards survival analysisSystematic reviewComprehensive literature searchCheckpoint inhibitorsDeath-1PD-1Platinum therapy
2018
Novel urinary biomarkers for the detection of bladder cancer: A systematic review
Tan W, Tan W, Tan M, Khetrapal P, Dong L, deWinter P, Feber A, Kelly J. Novel urinary biomarkers for the detection of bladder cancer: A systematic review. Cancer Treatment Reviews 2018, 69: 39-52. PMID: 29902678, DOI: 10.1016/j.ctrv.2018.05.012.Peer-Reviewed Original ResearchConceptsNegative predictive valuePositive predictive valueUrinary biomarkersBladder cancerReceiver operating characteristicRisk of biasPredictive valueNon-muscle invasive bladder cancer patientsBiomarkers investigated to dateInvasive bladder cancer patientsDetection of bladder cancerDiagnosis of bladder cancerSystematic reviewNovel urinary biomarkersBladder cancer patientsQUADAS-2 toolCase-control studyAssessed risk of biasSpecificity of biomarkersPositive test resultsSystematic searchUrinary cytologySurveillance cystoscopyComprehensive systematic reviewQUADAS-2The role of circulating tumour cells and nucleic acids in blood for the detection of bladder cancer: A systematic review
Khetrapal P, Lee M, Tan W, Dong L, de Winter P, Feber A, Kelly J. The role of circulating tumour cells and nucleic acids in blood for the detection of bladder cancer: A systematic review. Cancer Treatment Reviews 2018, 66: 56-63. PMID: 29684744, DOI: 10.1016/j.ctrv.2018.03.007.Peer-Reviewed Original ResearchConceptsCirculating tumor cellsBladder cancerBlood-based biomarkersValidation cohortTumor cellsDiagnostic value of circulating tumor cellsCirculating tumor cell biomarkerDetection of bladder cancerSystematic reviewCell-free DNAIndependent validation cohortCirculating nucleic acidsSolid cancersAUC/ROC valueUrinary biomarkersMedian numberDiagnostic valueCancerBiomarker sensitivityBiomarkersNucleic acidsBladderSystematic searchCohortAUC/ROC
2016
Robotic Assisted Radical Cystectomy with Extracorporeal Urinary Diversion Does Not Show a Benefit over Open Radical Cystectomy: A Systematic Review and Meta-Analysis of Randomised Controlled Trials
Tan W, Khetrapal P, Tan W, Rodney S, Chau M, Kelly J. Robotic Assisted Radical Cystectomy with Extracorporeal Urinary Diversion Does Not Show a Benefit over Open Radical Cystectomy: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. PLOS ONE 2016, 11: e0166221. PMID: 27820855, PMCID: PMC5098822, DOI: 10.1371/journal.pone.0166221.Peer-Reviewed Original ResearchConceptsRobot-assisted radical cystectomyOpen radical cystectomyMeta-analysis of randomised controlled trialsExtracorporeal urinary diversionRandomised controlled trialsRadical cystectomyUrinary diversionPerioperative morbidityBladder cancerLack of Level I evidenceRobot-assisted radical cystectomy groupsPositive lymph node statusOutcomes of robot-assisted radical cystectomySystematic reviewControlled trialsOpen radical cystectomy patientsEfficacy of robot-assisted radical cystectomyInclusion criteriaPositive surgical marginsLymph node statusLymph node yieldMeta-analysisLevel I evidenceIntracorporeal urinary diversionWell-designed trialsPort-Site Metastases After Robotic Radical Cystectomy: A Systematic Review and Management Options
Khetrapal P, Tan W, Lamb B, Nathan S, Briggs T, Shankar A, Ramachandran N, Freeman A, Mitra A, Kelly J. Port-Site Metastases After Robotic Radical Cystectomy: A Systematic Review and Management Options. Clinical Genitourinary Cancer 2016, 15: 440-444. PMID: 28209455, DOI: 10.1016/j.clgc.2016.06.012.Peer-Reviewed Original ResearchConceptsRobot-assisted radical cystectomyPort-site metastasisRadical cystectomyCase of port-site metastasisLymph node-positive diseaseMuscle-invasive bladder cancerIntracorporeal robot-assisted radical cystectomySystematic reviewNode-positive diseaseSystematic review of MEDLINERobotic radical cystectomyIdentified 4 casesTreatment of chemotherapyReview of MEDLINEDisease-free statusSalvage chemotherapyPrimary tumorSurgical excisionMultimodal treatmentPublished studiesAggressive treatmentBladder cancerTreatment optionsEmbase databasesPatient factorsWell-Differentiated Papillary Mesothelioma of the Tunica Vaginalis: Case Report and Systematic Review of Literature
Tan W, Tan M, Tan W, Gan S, Pathmanathan R, Tan H, Tan W. Well-Differentiated Papillary Mesothelioma of the Tunica Vaginalis: Case Report and Systematic Review of Literature. Clinical Genitourinary Cancer 2016, 14: e435-e439. PMID: 27067374, DOI: 10.1016/j.clgc.2016.03.007.Peer-Reviewed Original Research