2023
Evolving systemic management of urothelial cancers
Tan W, Tan M, Alhalabi O, Campbell M, Kamat A, Gao J. Evolving systemic management of urothelial cancers. Current Opinion In Oncology 2023, 35: 186-199. PMID: 36966497, DOI: 10.1097/cco.0000000000000942.Peer-Reviewed Original ResearchConceptsPlatinum-based chemotherapyInvasive bladder cancerBladder cancerAntibody-drug conjugatesFibroblast growth factor receptorCheckpoint inhibitorsUrothelial carcinomaProgrammed cell death-ligand 1 inhibitorsLocalized muscle invasive bladder cancerImprove bladder cancer outcomesNonmuscle invasive bladder cancerTraditional platinum-based chemotherapyProgrammed cell death 1Management of urothelial carcinomaMuscle invasive bladder cancerImmune checkpoint inhibitorsCell death 1Third-line optionBladder cancer outcomesResponse to therapyGrowth factor receptorFood and Drug AdministrationDeath-1Second-lineSystemic treatment
2022
A systematic review and meta-analysis on delaying surgery for urothelial carcinoma of bladder and upper tract urothelial carcinoma: Implications for the COVID19 pandemic and beyond
Leow J, Tan W, Tan W, Tan T, Chan V, Tikkinen K, Kamat A, Sengupta S, Meng M, Shariat S, Roupret M, Decaestecker K, Vasdev N, Chong Y, Enikeev D, Giannarini G, Ficarra V, Teoh J, Collaborators O. A systematic review and meta-analysis on delaying surgery for urothelial carcinoma of bladder and upper tract urothelial carcinoma: Implications for the COVID19 pandemic and beyond. Frontiers In Surgery 2022, 9: 879774. PMID: 36268209, PMCID: PMC9577485, DOI: 10.3389/fsurg.2022.879774.Peer-Reviewed Original ResearchRadical nephro-ureterectomyAssociated with poor overall survivalRadical cystectomyNeoadjuvant chemotherapyPoor overall survivalOverall survivalUrothelial carcinomaSurvival outcomesUrothelial carcinoma of bladderAssociated with poor survival outcomesUpper tract urothelial carcinomaAssociated with overall survivalDiagnosis of UCBCancer-specific survivalInvasive urothelial carcinomaCarcinoma of bladderUrologic cancer surgeryMeta-analysisPoor survival outcomesSystematic reviewDefinitive surgeryBetween-study heterogeneityDelayed surgeryNephro-ureterectomyUpper tract
2018
Propensity-score-matched comparison of soft tissue surgical margins status between open and robotic-assisted radical cystectomy
Moschini M, Soria F, Mathieu R, Xylinas E, D'Andrea D, Tan W, Kelly J, Simone G, Tuderti G, Meraney A, Krishna S, Konety B, Zamboni S, Baumeister P, Mattei A, Briganti A, Montorsi F, Galucci M, Rink M, Karakiewicz P, Rouprêt M, Aziz A, Perry M, Rowe E, Koupparis A, Kassouf W, Scherr D, Ploussard G, Boorjian S, Sooriakumaran P, Shariat S, Urologists U. Propensity-score-matched comparison of soft tissue surgical margins status between open and robotic-assisted radical cystectomy. Urologic Oncology Seminars And Original Investigations 2018, 37: 179.e1-179.e7. PMID: 30446442, DOI: 10.1016/j.urolonc.2018.10.012.Peer-Reviewed Original ResearchMeSH KeywordsAgedCarcinoma, Transitional CellChemotherapy, AdjuvantCystectomyFemaleFollow-Up StudiesHumansLength of StayLymph Node ExcisionMaleMargins of ExcisionMiddle AgedPostoperative ComplicationsPropensity ScoreRetrospective StudiesRobotic Surgical ProceduresTreatment OutcomeUrinary BladderUrinary Bladder NeoplasmsConceptsSoft tissue surgical marginsRobotic-assisted radical cystectomyOpen radical cystectomyPositive soft tissue surgical marginsRARC groupSoft tissue surgical margin statusRadical cystectomyPropensity-score matchingRARC patientsOpen radical cystectomy groupImpact of surgical techniqueOpen radical cystectomy patientsNon-organ-confinedMultivariate logistic regression analysisOrgan-confined diseaseSurgical margin statusSubgroup of patientsPropensity-score-matched cohortLogistic regression analysisOncologic efficacySurgical marginsPrognostic factorsUrothelial carcinomaMargin statusSurgical technique