2022
In-Vitro Comparison of Single Limb and Dual Limb Circuit for Aerosol Delivery via Noninvasive Ventilation.
Tan W, Dai B, Xu D, Li L, Li J. In-Vitro Comparison of Single Limb and Dual Limb Circuit for Aerosol Delivery via Noninvasive Ventilation. Respiratory Care 2022, 67: 807-813. PMID: 35473786, DOI: 10.4187/respcare.09543.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, InhalationAdultAerosolsAlbuterolBronchodilator AgentsEquipment DesignHumansNebulizers and VaporizersNoninvasive VentilationConceptsDual-limb circuitNon-vented maskVibrating mesh nebulizerSingle-limb circuitNoninvasive ventilationAerosol deliveryVented maskMesh nebulizerExhalation portNo significant differenceSignificant differenceInspiratory limbY-pieceIn vitro comparisonSimulated lungNebulizer positionTidal volumeVentilation parametersAerosol depositionIn vitroVentilationICU ventilatorsLungDeliveryNebulizer
2021
The Use of Aerosolized Medications in Adult Intensive Care Unit Patients: A Prospective, Multicenter, Observational, Cohort Study
Lyu S, Li J, Wu M, He D, Fu T, Ni F, Tan X, Wu G, Pan B, Li L, Wang H, Zeng G, Ni Z, Tan W, Zong Y, Chen L, Liu P, Qin H, He P, Zhang L, An Y, Liang Z, Xie L, Li Y, Zhou M, Li Q, Zhao J, Fang B, Ma Y, Huang R, Guo W, Dong X, Huang X, MO G, Xia J, Xiao K, Zhao H, Kong X, Zhao H, Ma J, Gao P, Yang W, Han F, Dong Y, Ye L, Chen C, Bao Z, Liu Y, Zheng C, Miao L, Yao M, Wang W, Wei S, Li H, Luo F, Liang G, Li J, Zhang C, Dai L, Song L, Wang C, Wang S. The Use of Aerosolized Medications in Adult Intensive Care Unit Patients: A Prospective, Multicenter, Observational, Cohort Study. Journal Of Aerosol Medicine And Pulmonary Drug Delivery 2021, 34: 383-391. PMID: 34129389, DOI: 10.1089/jamp.2021.0004.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, InhalationAdultBronchodilator AgentsCohort StudiesHumansIntensive Care UnitsProspective StudiesConceptsIntensive care unitAerosol therapyAerosolized medicationsCohort studySide effectsShort-acting muscarinic antagonistsCombination of inhaled corticosteroidsChronic obstructive pulmonary disease exacerbationsIntensive care unit patientsSpontaneously breathing patientsAdult intensive care unit patientsAdult ICU patientsChinese ICUsBreathing patientsRespiratory supportMuscarinic antagonistInhaled corticosteroidsAdult patientsClinical outcomesMechanical ventilationDisease exacerbationUnit patientsCare unitConclusion:</i></b>ICU patientsThe Effect of Different Interfaces on the Aerosol Delivery with Vibrating Mesh Nebulizer During Noninvasive Positive Pressure Ventilation
Tan W, Dai B, Lu C, Hou H, Zhao H, Wang W, Kang J. The Effect of Different Interfaces on the Aerosol Delivery with Vibrating Mesh Nebulizer During Noninvasive Positive Pressure Ventilation. Journal Of Aerosol Medicine And Pulmonary Drug Delivery 2021, 34: 366-373. PMID: 33848443, DOI: 10.1089/jamp.2020.1623.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, InhalationAerosolsAlbuterolBronchodilator AgentsEquipment DesignNebulizers and VaporizersNoninvasive VentilationPositive-Pressure RespirationConceptsExpiratory positive airway pressureNoninvasive positive pressure ventilationInspiratory positive airway pressureVibrating mesh nebulizerPositive airway pressureAerosol deliveryPositive pressure ventilationMesh nebulizerAirway pressureNoninvasive ventilationPressure ventilationNebulizer positionStatistical differenceInspiratory tidal volumeInspiratory flowIntentional leaksVentilator circuitTidal volumeLung simulatorVentilationLungLeakDeliverySimulated lungNebulizer
2018
Effect of Jet Nebulization on Noninvasive Positive-Pressure Ventilation Administered with Noninvasive or Intensive Care Unit Ventilators: A Bench Study
Xu M, Dai B, Peng Y, Su J, Tan W, Zhao H. Effect of Jet Nebulization on Noninvasive Positive-Pressure Ventilation Administered with Noninvasive or Intensive Care Unit Ventilators: A Bench Study. Respiration 2018, 97: 355-362. PMID: 30544115, DOI: 10.1159/000494456.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, InhalationCritical CareIntensive Care UnitsPositive-Pressure RespirationTidal VolumeVentilators, MechanicalConceptsNoninvasive positive pressure ventilationIntensive care unitPositive pressure ventilationIntensive care unit ventilatorsNoninvasive ventilationEffect of jet nebulizationTidal volumeJet nebulizerPressure ventilationNoninvasive positive-pressure ventilationPositive-pressure ventilationAerosol inhalation therapyActual tidal volumeInvasive ventilationInhalation therapyAerosol therapyCare unitAcute settingDeliver drugsImpact of jet nebulizationPatientsInspiratory limbVentilationTherapyExhalation valve
2013
Influence of Exhalation Valve and Nebulizer Position on Albuterol Delivery During Noninvasive Positive Pressure Ventilation
Dai B, Kang J, Sun L, Tan W, Zhao H. Influence of Exhalation Valve and Nebulizer Position on Albuterol Delivery During Noninvasive Positive Pressure Ventilation. Journal Of Aerosol Medicine And Pulmonary Drug Delivery 2013, 27: 125-132. PMID: 23668546, DOI: 10.1089/jamp.2012.1024.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, InhalationAdrenergic beta-2 Receptor AgonistsAerosolsAlbuterolBronchodilator AgentsDrug Delivery SystemsEquipment DesignExhalationHumansInhalationLungModels, AnatomicMotionNebulizers and VaporizersNoninvasive VentilationPositive-Pressure RespirationPressureVentilators, MechanicalConceptsNoninvasive positive pressure ventilationEfficiency of aerosol deliveryAerosol deliveryPositive pressure ventilationExhalation portNebulizer positionVentilator circuitPressure ventilationSpontaneous breathingExpiratory pressureExhalation valveHigh inspiratory pressuresExpiratory pressure levelsOptimal clinical efficacyAlbuterol deliveryClinical efficacyNormal salineInspiratory pressureAlbuterol solutionClinical efficiencyAlbuterolBreathing circuitLung modelVentilationBreathing