2021
Delayed surgery for localised and metastatic renal cell carcinoma: a systematic review and meta-analysis for the COVID-19 pandemic
Chan V, Tan W, Leow J, Tan W, Ong W, Chiu P, Gurung P, Pirola G, Orecchia L, Liew M, Lee H, Wang Y, Chen I, Castellani D, Wroclawski M, Mayor N, Sathianathen N, Braga I, Liu Z, Moon D, Tikkinen K, Kamat A, Meng M, Ficarra V, Giannarini G, Teoh J. Delayed surgery for localised and metastatic renal cell carcinoma: a systematic review and meta-analysis for the COVID-19 pandemic. World Journal Of Urology 2021, 39: 4295-4303. PMID: 34031748, PMCID: PMC8143063, DOI: 10.1007/s00345-021-03734-1.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, Renal CellCommunicable Disease ControlCOVID-19HumansKidney NeoplasmsNephrectomySurvival RateTime-to-TreatmentConceptsMetastatic renal cell carcinomaRenal cell carcinomaLocalised RCCDelayed surgeryCytoreductive nephrectomyDeferred CNOverall survivalCell carcinomaTargeted therapyAssociated with worse cancer-specific survivalAssociated with better overall survivalT1a renal cell carcinomaEffect of delaying surgeryDeferred cytoreductive nephrectomyCancer-specific survivalMeta-analysisElective cancer surgeryNewcastle-Ottawa ScaleSystematic reviewComprehensive literature searchUpfront CNOncological effectivenessRisk of biasImmediate surgeryRandomised controlled trials
2020
Delayed blood transfusion is associated with mortality following radical cystectomy
Tan W, Wang Y, Trinh Q, Preston M, Kelly J, Hrouda D, Kibel A, Krasnow R, Liu J, Chung B, Chang S, Mossanen M. Delayed blood transfusion is associated with mortality following radical cystectomy. Scandinavian Journal Of Urology 2020, 54: 290-296. PMID: 32538224, DOI: 10.1080/21681805.2020.1777195.Peer-Reviewed Original ResearchConceptsDelayed blood transfusionEarly blood transfusionBlood transfusionRadical cystectomyBladder cancer treated with radical cystectomyPatients treated with radical cystectomyAssociated with 90-day mortalityIncreased 90-day mortalityTime of blood transfusionPrimary end pointRetrospective cohort studyMultivariate logistic regressionAssociated with mortalityDelayed transfusionMedian ageClinical deteriorationCystectomyHigher CCIOlder patientsTransfusionCohort studyEnd pointsPatient mortalityPatientsIndex admission
2019
Delayed nephrectomy has comparable long-term overall survival to immediate nephrectomy for cT1a renal cell carcinoma: A population-based analysis
Tan W, Trinh Q, Hayn M, Marchese M, Lipsitz S, Nabi J, Kilbridge K, Vale J, Khoubehi B, Kibel A, Sun M, Chang S, Sammon J. Delayed nephrectomy has comparable long-term overall survival to immediate nephrectomy for cT1a renal cell carcinoma: A population-based analysis. Urologic Oncology Seminars And Original Investigations 2019, 38: 74.e13-74.e20. PMID: 31864937, DOI: 10.1016/j.urolonc.2019.11.008.Peer-Reviewed Original ResearchConceptsRenal cell carcinomaCT1a renal cell carcinomaImmediate nephrectomyKaplan-Meier curvesOverall survivalCell carcinomaSurgical resectionRenal massesPatient ageTreatment armsCharlson Comorbidity Index 0Compare OS of patientsLong-term overall survivalInfluence of patient ageCox proportional hazards regression analysisEarly surgical resectionLong-term OSMedian patient ageProportional hazards regression analysisMedian follow-upNational Cancer DatabaseOS of patientsSmall renal massesInverse probabilityRecommended treatment option