2015
Epigenetics Markers of Metastasis and HPV-Induced Tumorigenesis in Penile Cancer
Feber A, Arya M, de Winter P, Saqib M, Nigam R, Malone P, Tan W, Rodney S, Lechner M, Freeman A, Jameson C, Muneer A, Beck S, Kelly J. Epigenetics Markers of Metastasis and HPV-Induced Tumorigenesis in Penile Cancer. Clinical Cancer Research 2015, 21: 1196-1206. PMID: 25538261, PMCID: PMC4351916, DOI: 10.1158/1078-0432.ccr-14-1656.Peer-Reviewed Original ResearchMeSH KeywordsCell Transformation, NeoplasticCell Transformation, ViralCluster AnalysisComputational BiologyCpG IslandsDNA MethylationEpigenesis, GeneticGene Expression ProfilingGene Expression Regulation, NeoplasticHumansLymph NodesLymphatic MetastasisMaleNeoplasm MetastasisPapillomaviridaePapillomavirus InfectionsPenile NeoplasmsRepetitive Sequences, Nucleic AcidConceptsHead and neck squamous cell carcinomaCervical squamous cell carcinomaSquamous cell carcinomaPenile cancerHPV statusEpigenetic alterationsCell carcinomaMethylation variable positionsEpi-signatureLymph node metastases markerNeck squamous cell carcinomaHPV-driven malignanciesTumor supressor geneLymph node metastasisMarkers of metastasisPredictors of survivalGenome-wide methylation arrayHPV-induced tumorigenesisHPV infectionRare malignancyOverall survivalQ-MSPNode metastasisTumor tissuesHPV
2014
Management of Node-Positive Bladder Cancer After Neoadjuvant Chemotherapy and Radical Cystectomy: A Survey of Current UK Practice
Tan W, Lamb B, Payne H, Hughes S, Green J, Lane T, Adshead J, Boustead G, Vasdev N. Management of Node-Positive Bladder Cancer After Neoadjuvant Chemotherapy and Radical Cystectomy: A Survey of Current UK Practice. Clinical Genitourinary Cancer 2014, 13: e153-e158. PMID: 25510376, DOI: 10.1016/j.clgc.2014.11.006.Peer-Reviewed Original ResearchConceptsNeoadjuvant chemotherapy regimenNeoadjuvant chemotherapyPositive lymph nodesRadical cystectomyAdjuvant chemotherapyTreatment of patientsBladder cancerNodal diseaseLymph nodesIndication of adjuvant chemotherapyNode-positive bladder cancerPresence of disease progressionResponse to NACCancer CenterMuscle-invasive bladder cancerCycles of gemcitabineAdvanced bladder cancerPatient performance statusUro-oncologistsChemotherapy regimenPerformance statusLack of published evidenceDisease progressionChemotherapyPatients