2022
Comparison of Long-term Outcomes for Young and Healthy Patients with cT1a and cT3a Renal Cell Carcinoma Treated with Partial Nephrectomy
Tan W, Koelker M, Campain N, Cole A, Labban M, Mossanen M, Barod R, Kibel A, Chang S, Bex A, Trinh Q. Comparison of Long-term Outcomes for Young and Healthy Patients with cT1a and cT3a Renal Cell Carcinoma Treated with Partial Nephrectomy. European Urology Focus 2022, 9: 333-335. PMID: 36241545, DOI: 10.1016/j.euf.2022.09.018.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, Renal CellHumansKidneyKidney NeoplasmsMargins of ExcisionNeoplasm StagingNephrectomyConceptsRenal cell carcinomaLocally advanced kidney cancerPositive surgical marginsPartial nephrectomyAdvanced kidney cancerSurgical marginsKidney cancerRate of surgical marginComparison of long-term outcomesNational Cancer DatabaseMedian follow-upPatients aged <Cox proportional-hazards modelLong-term outcomesPresence of tumorCharlson Comorbidity IndexChronic kidney diseaseProportional-hazards modelCT1a tumorsCT1b groupHigher ACMNephron preservationCT stagingSolitary kidneyCell carcinoma
2021
Delayed surgery for localised and metastatic renal cell carcinoma: a systematic review and meta-analysis for the COVID-19 pandemic
Chan V, Tan W, Leow J, Tan W, Ong W, Chiu P, Gurung P, Pirola G, Orecchia L, Liew M, Lee H, Wang Y, Chen I, Castellani D, Wroclawski M, Mayor N, Sathianathen N, Braga I, Liu Z, Moon D, Tikkinen K, Kamat A, Meng M, Ficarra V, Giannarini G, Teoh J. Delayed surgery for localised and metastatic renal cell carcinoma: a systematic review and meta-analysis for the COVID-19 pandemic. World Journal Of Urology 2021, 39: 4295-4303. PMID: 34031748, PMCID: PMC8143063, DOI: 10.1007/s00345-021-03734-1.Peer-Reviewed Original ResearchConceptsMetastatic renal cell carcinomaRenal cell carcinomaLocalised RCCDelayed surgeryCytoreductive nephrectomyDeferred CNOverall survivalCell carcinomaTargeted therapyAssociated with worse cancer-specific survivalAssociated with better overall survivalT1a renal cell carcinomaEffect of delaying surgeryDeferred cytoreductive nephrectomyCancer-specific survivalMeta-analysisElective cancer surgeryNewcastle-Ottawa ScaleSystematic reviewComprehensive literature searchUpfront CNOncological effectivenessRisk of biasImmediate surgeryRandomised controlled trials
2020
Inequity in selective referral to high-volume hospitals for genitourinary malignancies
Berg S, Tully K, Sahraoui A, Tan W, Krimphove M, Marchese M, Lipsitz S, Noldus J, Trinh Q. Inequity in selective referral to high-volume hospitals for genitourinary malignancies. Urologic Oncology Seminars And Original Investigations 2020, 38: 582-589. PMID: 32217041, DOI: 10.1016/j.urolonc.2020.02.013.Peer-Reviewed Original ResearchConceptsHigh-volume hospitalsBladder cancerPredictors of treatmentCancer patientsRadical prostatectomyProstate cancerMuscle-invasive urothelial bladder cancerNegative predictors of treatmentBlack raceNational Cancer DatabaseNonmetastatic prostate cancerUrothelial bladder cancerProstate cancer patientsBladder cancer patientsMultivariate logistic regression modelAssociated with lower ratesKidney cancer patientsPrivate insurance statusAssociated with lower oddsAssociated with greater oddsLow-volume hospitalsRadical cystectomyReceipt of treatmentGenitourinary malignanciesPerioperative morbidity
2019
Delayed nephrectomy has comparable long-term overall survival to immediate nephrectomy for cT1a renal cell carcinoma: A population-based analysis
Tan W, Trinh Q, Hayn M, Marchese M, Lipsitz S, Nabi J, Kilbridge K, Vale J, Khoubehi B, Kibel A, Sun M, Chang S, Sammon J. Delayed nephrectomy has comparable long-term overall survival to immediate nephrectomy for cT1a renal cell carcinoma: A population-based analysis. Urologic Oncology Seminars And Original Investigations 2019, 38: 74.e13-74.e20. PMID: 31864937, DOI: 10.1016/j.urolonc.2019.11.008.Peer-Reviewed Original ResearchConceptsRenal cell carcinomaCT1a renal cell carcinomaImmediate nephrectomyKaplan-Meier curvesOverall survivalCell carcinomaSurgical resectionRenal massesPatient ageTreatment armsCharlson Comorbidity Index 0Compare OS of patientsLong-term overall survivalInfluence of patient ageCox proportional hazards regression analysisEarly surgical resectionLong-term OSMedian patient ageProportional hazards regression analysisMedian follow-upNational Cancer DatabaseOS of patientsSmall renal massesInverse probabilityRecommended treatment option