FEP-Guided Selection of Bicyclic Heterocycles in Lead Optimization for Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase
Kim JT, Hamilton AD, Bailey CM, Domoal R, Wang L, Anderson KS, Jorgensen WL. FEP-Guided Selection of Bicyclic Heterocycles in Lead Optimization for Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase. Journal Of The American Chemical Society 2006, 128: 15372-15373. PMID: 17131993, DOI: 10.1021/ja066472g.Peer-Reviewed Original ResearchAnti-HIV AgentsBridged Bicyclo Compounds, HeterocyclicDrug DesignHIV Reverse TranscriptaseModels, MolecularMolecular StructureNanostructuresReverse Transcriptase Inhibitors