2001
Superficial acral fibromyxoma: A clinicopathologic and immunohistochemical analysis of 37 cases of a distinctive soft tissue tumor with a predilection for the fingers and toes
Fetsch J, Laskin W, Miettinen M. Superficial acral fibromyxoma: A clinicopathologic and immunohistochemical analysis of 37 cases of a distinctive soft tissue tumor with a predilection for the fingers and toes. Human Pathology 2001, 32: 704-714. PMID: 11486169, DOI: 10.1053/hupa.2001.25903.Peer-Reviewed Original ResearchConceptsSoft tissue tumorsDistinctive soft tissue tumorLocal excisionTissue tumorsAcral myxoinflammatory fibroblastic sarcomaFascicular growth patternEpithelial membrane antigenMild nuclear atypiaMyxoinflammatory fibroblastic sarcomaStellate-shaped cellsProgressive diseaseClinicopathologic featuresHMB-45Surgical interventionImmunohistochemical findingsResection specimensSurgical specimensFibrous histiocytomaPartial excisionDifferential diagnosisLesional cellsStudy groupMast cellsNuclear atypiaImmunohistochemical analysis
2000
The “neurothekeoma”: Immunohistochemical analysis distinguishes the true nerve sheath myxoma from its mimics
Laskin W, Fetsch J, Miettinen M. The “neurothekeoma”: Immunohistochemical analysis distinguishes the true nerve sheath myxoma from its mimics. Human Pathology 2000, 31: 1230-1241. PMID: 11070116, DOI: 10.1053/hupa.2000.18474.Peer-Reviewed Original ResearchConceptsGlial fibrillary acidic proteinNerve sheath myxomaSpindled cellsPeak incidenceFemale ratioLow-affinity nerve growth factor receptorDense collagenAlpha-smooth muscle actinAnti-neurofilament proteinSoft Tissue RegistryNerve sheath tumorsNerve growth factor receptorDecades of lifeEpithelial membrane antigenFibrillary acidic proteinCollagen type IV expressionGrowth factor receptorSheath tumorsAnatomic distributionLeu-7Consistent immunoreactivityMyxoid variantTissue RegistryImmunohistochemical analysisEpithelioid cells
1997
Superficial Angiomyxoma (Cutaneous Myxoma) A Clinicopathologic Study of 17 Cases Arising in the Genital Region
Fetsch J, Laskin W, Tavassoli F. Superficial Angiomyxoma (Cutaneous Myxoma) A Clinicopathologic Study of 17 Cases Arising in the Genital Region. International Journal Of Gynecological Pathology 1997, 16: 325-334. PMID: 9421071, DOI: 10.1097/00004347-199710000-00006.Peer-Reviewed Original ResearchConceptsSuperficial angiomyxomaGenital regionGlial fibrillary acidic proteinSite of involvementMuscle-specific actinFibrillary acidic proteinSmooth muscle actinYears 11 monthsMedian followClinicopathologic studyMale patientsAntigen modulationProgesterone receptorFibroblast-like cellsPainless massLabium majusEstrogen receptorMedical attentionPatientsMuscle actinS100 proteinCarney complexAcidic proteinMons pubisAngiomyxoma
1996
Aggressive angiomyxoma: A clinicopathologic study of 29 female patients
Fetsch J, Laskin W, Lefkowitz M, Kindblom L, Meis‐Kindblom J. Aggressive angiomyxoma: A clinicopathologic study of 29 female patients. Cancer 1996, 78: 79-90. PMID: 8646730, DOI: 10.1002/(sici)1097-0142(19960701)78:1<79::aid-cncr13>3.0.co;2-4.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedDesminFemaleHumansMiddle AgedMyxomaNeoplasm ProteinsPelvic NeoplasmsVimentinConceptsAggressive angiomyxomaSmooth muscle differentiationInitial resectionMesenchymal tumorsNeoplastic cellsFocal smooth muscle differentiationTumor related deathUncommon mesenchymal tumorMuscle-specific actinArmed Forces InstituteAbundant eosinophilic cytoplasmSmooth muscle actinClinicopathologic studyLocal recurrenceMetastatic diseaseFemale patientsPathologic featuresRecurrent tumorsPeak incidenceProgesterone receptorRelated deathsEosinophilic cytoplasmSpindled cellsMyofibroblastic featuresEdema fluid
1995
Desmoplastic malignant melanoma
Skelton H, Smith K, Laskin W, McCarthy W, Gagnier J, Graham J, Lupton G. Desmoplastic malignant melanoma. Journal Of The American Academy Of Dermatology 1995, 32: 717-725. PMID: 7722014, DOI: 10.1016/0190-9622(95)91448-x.Peer-Reviewed Original ResearchConceptsDisease-free survival ratesDesmoplastic malignant melanomaMalignant melanomaSurvival rateHistologic featuresCases of DMMOverall histologic featuresDisease-free survivalArmed Forces InstituteBetter prognosisHMB-45Histologic findingsImmunohistochemical evaluationTumor locationImmunohistochemical studyTumor depthUncommon variantBiologic potentialStromal mucinAdequate materialMelanomaTumorsRelative rarityPatientsNeural differentiation
1991
Epithelioid Variant of Malignant Peripheral Nerve Sheath Tumor (Malignant Epithelioid Schwannoma)
Laskin W, Weiss S, Bratthauer G. Epithelioid Variant of Malignant Peripheral Nerve Sheath Tumor (Malignant Epithelioid Schwannoma). The American Journal Of Surgical Pathology 1991, 15: 1136-1145. PMID: 1746681, DOI: 10.1097/00000478-199112000-00004.Peer-Reviewed Original ResearchConceptsNerve sheath tumorsDeep soft tissuesMalignant peripheral nerve sheath tumorPeripheral nerve sheath tumorsSuperficial soft tissuesSheath tumorsSoft tissueBenign nerve sheath tumorsRounded epithelioid cellsClear cell carcinomaNeuron-specific enolaseMelanoma-associated antigensMalignant rhabdoid tumorMajority of casesVague nodulesMetastatic diseaseAsymptomatic massEpithelioid variantCell carcinomaHistologic patternFavorable coursePleomorphic sarcomaEpithelioid patternBiologic behaviorLinear immunoreactivity
1989
Solitary cutaneous plexiform neurilemmoma (schwannoma): a clinicopathologic, immunohistochemical, and ultrastructural study of 11 cases.
Kao G, Laskin W, Olsen T. Solitary cutaneous plexiform neurilemmoma (schwannoma): a clinicopathologic, immunohistochemical, and ultrastructural study of 11 cases. Modern Pathology 1989, 2: 20-6. PMID: 2493641.Peer-Reviewed Original ResearchConceptsBenign peripheral nerve sheath tumorsRare benign peripheral nerve sheath tumorPeripheral nerve sheath tumorsTumor cellsGlial fibrillary acid proteinSpindle-shaped tumor cellsNerve sheath tumorsNeuron-specific enolasePlexiform growth patternDistinct cytoplasmic bordersSpindle-shaped cellsVon Recklinghausen's neurofibromatosisMedian agePatient ageSheath tumorsPainful nodulesClinicopathologic correlationNerve fibersMyxoid stromaSchwann cellsNodular variantNuclear palisadingGross examinationVerocay bodiesCytoplasmic borders