1990
Stz-Induced Diabetes in Shr and Renovascular Hypertensive Rats: Dissociation Between Changes in Arterial Pressure and Vascular Collagen Synthesis
Mariani M, Sessa W, Chichester C, Rodgers R. Stz-Induced Diabetes in Shr and Renovascular Hypertensive Rats: Dissociation Between Changes in Arterial Pressure and Vascular Collagen Synthesis. Clinical And Experimental Hypertension 1990, 12: 1003-1019. PMID: 2245511, DOI: 10.3109/10641969009073514.Peer-Reviewed Original ResearchConceptsRenovascular hypertensive ratsVascular collagen synthesisArterial pressureHypertensive ratsCollagen synthesisSTZ induced diabetesLeft renal arteryNormotensive WKY ratsSTZ-induced diabetesWistar-Kyoto ratsNondiabetic SHRRVH ratsRenovascular hypertensionWKY controlsNormotensive controlsRenal arteryWKY ratsProlyl hydroxylase activitySHRDiabetesRatsHydroxylase activityProline incorporationHypertensionWKY
1989
Manipulation of cytochrome P-450 dependent renal thromboxane synthase activity in spontaneously hypertensive rats
Sessa W, Abraham N, Escalante B, Schwartzman M. Manipulation of cytochrome P-450 dependent renal thromboxane synthase activity in spontaneously hypertensive rats. Journal Of Hypertension 1989, 7: 37-42. PMID: 2708811, DOI: 10.1097/00004872-198901000-00006.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlood PressureHypertensionKidneyRatsRats, Inbred SHRThromboxane-A SynthaseTinTin CompoundsConceptsHeme oxygenase activityThromboxane synthase activityHypertensive ratsRenal heme oxygenase activitySeven-week-old SHRRenal cortical microsomesSystolic blood pressureMicrosomal heme oxygenase activityRenal cytochrome PCytochrome PSynthase activityThromboxane A2 formationCortical microsomesBlood pressureOxygenase activityBody weightA2 formationHemoprotein synthesisConsecutive daysControl levelsThromboxane synthaseSHRRatsHeme contentHeme availability