2024
The Influence of DNA Repair Genes and Prenatal Tobacco Exposure on Risk of Childhood Acute Lymphoblastic Leukemia-A Gene-Environment Interaction Study.
Wang X, Zhong C, Ma X, Metayer C, Mancuso N, Gauderman W, Wiemels J. The Influence of DNA Repair Genes and Prenatal Tobacco Exposure on Risk of Childhood Acute Lymphoblastic Leukemia-A Gene-Environment Interaction Study. Cancer Epidemiology Biomarkers & Prevention 2024 PMID: 39495115, DOI: 10.1158/1055-9965.epi-24-1037.Peer-Reviewed Original ResearchPrenatal tobacco exposureTobacco exposureGene-environment interaction studiesNon-Latino white childrenAcute lymphoblastic leukemia riskChildhood ALL riskRepair genesGene-environment interactionsAcute lymphoblastic leukemiaStatistically significant interactionPotential risk factorsDNA repair genesTobacco smokeLatino childrenPediatric oncologyALL riskTargeted preventionWhite childrenLogistic regressionEpidemiological studiesEnvironmental exposuresRisk factorsTobaccoGenotype dataSignificant interaction
2021
Genetic susceptibility to hepatocellular carcinoma in chromosome 22q13.31, findings of a genome‐wide association study
Wang Z, Budhu AS, Shen Y, Wong LL, Hernandez BY, Tiirikainen M, Ma X, Irwin ML, Lu L, Zhao H, Lim JK, Taddei T, Mishra L, Pawlish K, Stroup A, Brown R, Nguyen MH, Koshiol J, Hernandez MO, Forgues M, Yang H, Lee M, Huang Y, Iwasaki M, Goto A, Suzuki S, Matsuda K, Tanikawa C, Kamatani Y, Mann D, Guarnera M, Shetty K, Thomas CE, Yuan J, Khor CC, Koh W, Risch H, Wang XW, Yu H. Genetic susceptibility to hepatocellular carcinoma in chromosome 22q13.31, findings of a genome‐wide association study. JGH Open 2021, 5: 1363-1372. PMID: 34950780, PMCID: PMC8674550, DOI: 10.1002/jgh3.12682.Peer-Reviewed Original ResearchNonalcoholic fatty liver diseaseCase-control studyHepatocellular carcinomaSingle nucleotide polymorphismsChronic hepatitis C virus (HCV) infectionHepatitis C virus infectionGenetic susceptibilityC virus infectionLong-term alcohol useFatty liver diseaseUS case-control studyBody mass indexMajor risk factorGenome-wide association studiesHCV infectionCohort studyLiver diseaseCigarette smokingMass indexRisk factorsHCC casesVirus infectionGene-environment interactionsUS populationDisease risk