2019
Immunoepidemiology of Cancer
Ma X, Wang R. Immunoepidemiology of Cancer. 2019, 215-224. DOI: 10.1007/978-3-030-25553-4_13.Peer-Reviewed Original ResearchImmune system functionTypes of cancerImmunological factorsCancer immunotherapyTreatment modalitiesChronic diseasesRadiation therapyEpidemiological studiesDrug AdministrationImmunotherapyInfectious diseasesCancerDiseaseExciting new eraSystem functionChemotherapySurgeryImmunoepidemiologyEtiologyTherapyYearsInfectionAdministrationImportant role
2016
In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia
Francis SS, Wallace AD, Wendt GA, Li L, Liu F, Riley LW, Kogan S, Walsh KM, de Smith AJ, Dahl GV, Ma X, Delwart E, Metayer C, Wiemels JL. In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia. Blood 2016, 129: 1680-1684. PMID: 27979823, PMCID: PMC5364339, DOI: 10.1182/blood-2016-07-723148.Peer-Reviewed Original ResearchConceptsAcute lymphoblastic leukemiaCMV infectionCytomegalovirus infectionLymphoblastic leukemiaChildhood acute lymphoblastic leukemiaUtero cytomegalovirus infectionCongenital CMV infectionCommon childhood cancerActive viral transcriptionBone marrow specimensNon-Hispanic whitesTiming of infectionNewborn blood samplesEtiologic roleRisk factorsChildhood cancerHealthy controlsHigh prevalenceMarrow specimensLeukemia blastsBlood samplesPrenatal originEtiologic agentInfectionHispanic children
2010
Early life exposure to infections and risk of childhood acute lymphoblastic leukemia
Urayama KY, Ma X, Selvin S, Metayer C, Chokkalingam AP, Wiemels JL, Does M, Chang J, Wong A, Trachtenberg E, Buffler PA. Early life exposure to infections and risk of childhood acute lymphoblastic leukemia. International Journal Of Cancer 2010, 128: 1632-1643. PMID: 21280034, PMCID: PMC3165002, DOI: 10.1002/ijc.25752.Peer-Reviewed Original ResearchConceptsNorthern California Childhood Leukemia StudyAcute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaNon-Hispanic white childrenEarly life exposureDaycare attendanceLymphoblastic leukemiaEar infectionsLife exposureHispanic childrenCommon childhood infectionsAge 6 monthsWhite childrenCalifornia Childhood Leukemia StudyBirth orderChildhood Leukemia StudyChildhood infectionsCommon infectionsProtective roleInfectionSociodemographic differencesLeukemia StudyHispanic populationChildrenRiskA meta-analysis of the association between day-care attendance and childhood acute lymphoblastic leukaemia
Urayama KY, Buffler PA, Gallagher ER, Ayoob JM, Ma X. A meta-analysis of the association between day-care attendance and childhood acute lymphoblastic leukaemia. International Journal Of Epidemiology 2010, 39: 718-732. PMID: 20110276, PMCID: PMC2878455, DOI: 10.1093/ije/dyp378.Peer-Reviewed Original ResearchConceptsDay care attendanceAcute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaLymphoblastic leukemiaOdds ratioRisk of childhoodCase-control studyEarly life exposureRandom-effects modelCommon infectionsSubgroup analysisProphylactic interventionsInfluence of timingObservational studyChildhood leukemiaStudy heterogeneityPubMed databaseInfected individualsRisk estimatesSimilar findingsLeukemiaInfectionEarly childhoodRare responsesEffects model
2008
Infection and pediatric acute lymphoblastic leukemia
Ma X, Urayama K, Chang J, Wiemels JL, Buffler PA. Infection and pediatric acute lymphoblastic leukemia. Blood Cells Molecules And Diseases 2008, 42: 117-120. PMID: 19064328, PMCID: PMC2834409, DOI: 10.1016/j.bcmd.2008.10.006.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge of OnsetCase-Control StudiesChildChild Day Care CentersChild, PreschoolClone CellsCocarcinogenesisEmploymentForecastingHumansInfantInfectionsModels, BiologicalMutationNorth CarolinaParentsPrecursor B-Cell Lymphoblastic Leukemia-LymphomaPrecursor Cell Lymphoblastic Leukemia-LymphomaProspective StudiesRisk FactorsVaccinationConceptsNorthern California Childhood Leukemia StudyVaccination historyPediatric acute lymphoblastic leukemiaAcute lymphoblastic leukemiaCalifornia Childhood Leukemia StudyChild's vaccination historyChildhood Leukemia StudyDaycare attendanceLymphoblastic leukemiaInfectious agentsImmune systemLeukemia StudyChildren's exposureInfectionRecent findingsExposureSocial contactLeukemiaExposure to infections through day-care attendance and risk of childhood leukaemia
Urayama KY, Ma X, Buffler PA. Exposure to infections through day-care attendance and risk of childhood leukaemia. Radiation Protection Dosimetry 2008, 132: 259-266. PMID: 18940822, PMCID: PMC2879097, DOI: 10.1093/rpd/ncn271.Peer-Reviewed Original ResearchConceptsDay care attendanceRisk of childhoodAcute lymphoblastic leukemiaChildhood leukemiaCommon infectionsMore common infectionsNon-Hispanic white childrenNorthern California Childhood Leukemia StudyCommon B-cell precursorDose-response effectPrevious epidemiological studiesCalifornia Childhood Leukemia StudyChildhood Leukemia StudyB cell precursorsDay care settingsSummary measuresLymphoblastic leukemiaEpidemiological studiesNumber of childrenMajority of studiesInfectionLeukemiaLeukemia StudySocial contactRelevant studies
2005
Ethnic Difference in Daycare Attendance, Early Infections, and Risk of Childhood Acute Lymphoblastic Leukemia
Ma X, Buffler PA, Wiemels JL, Selvin S, Metayer C, Loh M, Does MB, Wiencke JK. Ethnic Difference in Daycare Attendance, Early Infections, and Risk of Childhood Acute Lymphoblastic Leukemia. Cancer Epidemiology Biomarkers & Prevention 2005, 14: 1928-1934. PMID: 16103439, DOI: 10.1158/1055-9965.epi-05-0115.Peer-Reviewed Original ResearchConceptsNon-Hispanic white childrenAcute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaDaycare attendanceLymphoblastic leukemiaC-ALLOdds ratioEarly infectionWhite childrenNorthern California Childhood Leukemia StudyPossible etiologic roleRisk of childhoodEthnic differencesCalifornia Childhood Leukemia StudyChildhood Leukemia StudyDose-response relationshipImportant ethnic differencesEar infectionsEtiologic roleInfectious agentsMagnitude of effectInfectionDisease hypothesisLeukemia StudyHispanic children408: Ethnic Difference in Daycare Attendance, Early Infections, and Risk of Childhood Acute Lymphoblastic Leukemia
Ma X, Buffler P, Wiemels J, Selvin S, Loh M, Metayer C, Does M, Wiencke J. 408: Ethnic Difference in Daycare Attendance, Early Infections, and Risk of Childhood Acute Lymphoblastic Leukemia. American Journal Of Epidemiology 2005, 161: s102-s102. DOI: 10.1093/aje/161.supplement_1.s102c.Peer-Reviewed Original Research