2022
Accelerated epigenetic aging in newborns with Down syndrome
Xu K, Li S, Muskens IS, Elliott N, Myint SS, Pandey P, Hansen HM, Morimoto LM, Kang AY, Ma X, Metayer C, Mueller BA, Roberts I, Walsh KM, Horvath S, Wiemels JL, de Smith A. Accelerated epigenetic aging in newborns with Down syndrome. Aging Cell 2022, 21: e13652. PMID: 35661546, PMCID: PMC9282838, DOI: 10.1111/acel.13652.Peer-Reviewed Original ResearchConceptsDown syndromeAge accelerationEpigenetic age accelerationGestational age accelerationEarly-onset Alzheimer's diseaseTransient abnormal myelopoiesisPotential confounding factorsEpigenetic agingPremature agingSomatic GATA1 mutationsDS patientsAbnormal myelopoiesisBlood cell proportionsNewbornsAlzheimer's diseaseConfounding factorsBrain tissueCell proportionGATA1 mutationsEndocrine systemBloodTargeted sequencingSomatic mutationsSyndromeDisease
2005
Vaccination history and risk of childhood leukaemia
Ma X, Does MB, Metayer C, Russo C, Wong A, Buffler PA. Vaccination history and risk of childhood leukaemia. International Journal Of Epidemiology 2005, 34: 1100-1109. PMID: 15951359, DOI: 10.1093/ije/dyi113.Peer-Reviewed Original ResearchConceptsChildhood leukemiaB vaccineHaemophilus influenzae type b vaccineInfluenzae type b vaccineConditional logistic regression analysisBirth certificate controlsType b vaccineHepatitis B vaccineNorthern California Childhood Leukemia StudyCase-control studyRole of vaccinationNumber of dosesType of vaccineRisk of leukemiaPotential confounding factorsLogistic regression analysisCalifornia Childhood Leukemia StudyChildhood Leukemia StudyDetailed exposure assessmentNumber of administrationsHib vaccinationHib vaccineVaccination historyIncident casesMore doses