2023
One-Carbon (Folate) Metabolism Pathway at Birth and Risk of Childhood Acute Lymphoblastic Leukemia: A Biomarker Study in Newborns
Metayer C, Imani P, Dudoit S, Morimoto L, Ma X, Wiemels J, Petrick L. One-Carbon (Folate) Metabolism Pathway at Birth and Risk of Childhood Acute Lymphoblastic Leukemia: A Biomarker Study in Newborns. Cancers 2023, 15: 1011. PMID: 36831356, PMCID: PMC9953980, DOI: 10.3390/cancers15041011.Peer-Reviewed Original ResearchAcute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaOne-carbon metabolism nutrientsRace/ethnicityLymphoblastic leukemiaFolic acid intakeTime of conceptionOne-carbon metabolism pathwaySubsequent leukemiaFirst trimesterAcid intakeCommon cancerDNA methylation programmingChildhood leukemiaLeukemiaNegative findingsBlood spotsBiomarker studiesPathway metabolitesFolic acidAges 0Key vitaminsPregnancyLast weekFolate pathway
2002
Critical windows of exposure to household pesticides and risk of childhood leukemia.
Ma X, Buffler PA, Gunier RB, Dahl G, Smith MT, Reinier K, Reynolds P. Critical windows of exposure to household pesticides and risk of childhood leukemia. Environmental Health Perspectives 2002, 110: 955-960. PMID: 12204832, PMCID: PMC1240997, DOI: 10.1289/ehp.02110955.Peer-Reviewed Original ResearchConceptsHigh riskChildhood leukemiaNorthern California Childhood Leukemia StudyPotential etiologic roleCalifornia Childhood Leukemia StudyHousehold pesticidesLocation of exposureChildhood Leukemia StudyHousehold pesticide exposureBirth RegistryControl subjectsEtiologic roleElevated riskSignificant associationLeukemiaPregnancyCritical windowLeukemia StudyLate exposureFrequent exposurePesticide exposureRiskExposureYear 2Year 1