2020
Socioeconomic status and childhood central nervous system tumors in California
Francis SS, Wang R, Enders C, Prado I, Wiemels JL, Ma X, Metayer C. Socioeconomic status and childhood central nervous system tumors in California. Cancer Causes & Control 2020, 32: 27-39. PMID: 33113073, DOI: 10.1007/s10552-020-01348-3.Peer-Reviewed Original ResearchConceptsPrimary CNS tumorsCentral nervous system tumorsChildhood CNS tumorsCNS tumorsNervous system tumorsSocioeconomic statusSystem tumorsChildhood central nervous system tumorsCalifornia Cancer RegistryCalifornia birth recordsSubset of subjectsHigher socioeconomic statusCancer RegistryCancer mortalitySubgroup analysisRisk factorsChildhood cancerSubsequent riskEmbryonal tumorsParental socioeconomic statusInsurance utilizationBirth recordsTumorsMedian household incomeSpecific exposuresSpatial-Temporal Cluster Analysis of Childhood Cancer in California.
Francis SS, Enders C, Hyde R, Gao X, Wang R, Ma X, Wiemels JL, Selvin S, Metayer C. Spatial-Temporal Cluster Analysis of Childhood Cancer in California. Epidemiology 2020, 31: 214-223. PMID: 31596791, PMCID: PMC9005107, DOI: 10.1097/ede.0000000000001121.Peer-Reviewed Original ResearchConceptsMalignant gonadal germ cell tumorsGonadal germ cell tumorsGerm cell tumorsAcute lymphoblastic leukemiaChildhood cancerCell tumorsChildhood acute lymphoblastic leukemiaYears of ageRace/ethnicity-matched controlsEthnicity-matched controlsSpace-time cluster analysisEpidemiologic featuresHodgkin's lymphomaLymphoblastic leukemiaBirth addressHealth professionalsCancerSpace-time clustersTumorsAgeSaTScanTemporal cluster analysisFurther researchEvidenceLymphoma
2015
A Heritable Missense Polymorphism in CDKN2A Confers Strong Risk of Childhood Acute Lymphoblastic Leukemia and Is Preferentially Selected during Clonal Evolution
Walsh KM, de Smith AJ, Hansen HM, Smirnov IV, Gonseth S, Endicott AA, Xiao J, Rice T, Fu CH, McCoy LS, Lachance DH, Eckel-Passow JE, Wiencke JK, Jenkins RB, Wrensch MR, Ma X, Metayer C, Wiemels JL. A Heritable Missense Polymorphism in CDKN2A Confers Strong Risk of Childhood Acute Lymphoblastic Leukemia and Is Preferentially Selected during Clonal Evolution. Cancer Research 2015, 75: 4884-4894. PMID: 26527286, PMCID: PMC4651745, DOI: 10.1158/0008-5472.can-15-1105.Peer-Reviewed Original ResearchConceptsAcute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaLymphoblastic leukemiaCancer riskRisk allelesGeneral cancer riskPancreatic cancer riskGenome-wide association studiesCase-control populationCDKN2A variantsProtective allelesTumor growthClonal expansionChromosome 9p21.3Hispanic childrenMissense polymorphismStrong riskMissense variantsClonal evolutionRiskLeukemiaTumorsAllelic imbalanceEuropean ancestryPolymorphism